Gut microbial-derived short-chain fatty acids and bone: a potential role in fracture healing [PDF]
European Cells & Materials, 2021 Bone healing complications such as delayed healing or non-union affect 5-10 % of patients with a long-bone fracture and lead to reduced quality of life and increased health-care costs.
A Wallimann +7 more
doaj +1 more source
Low Dose of Propranolol Does Not Affect Rat Osteotomy Healing and Callus Strength [PDF]
, 2014 Experimental studies suggest that the β‐blocker propranolol stimulates bone formation but little work has investigated its effect on fracture healing. In this study, we examined if a low dose of propranolol, previously shown to be preventive against bone
Apel +39 more
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Focus on bone healing: new strategies for improvement of bone healing [PDF]
European Journal of Trauma and Emergency Surgery, 2020 Malreduction after tibial plateau fractures mainly occurs due to insufficient visualization of the articular surface. In 85% of all C-type fractures an involvement of the posterolateral-central segment is observed, which is the main region of malreduction.
openaire +5 more sources
Adjuvant Drug-Assisted Bone Healing: Advances and Challenges in Drug Delivery Approaches
Pharmaceutics, 2020 Bone defects of critical size after compound fractures, infections, or tumor resections are a challenge in treatment. Particularly, this applies to bone defects in patients with impaired bone healing due to frequently occurring metabolic diseases (above ...
Rebecca Rothe +6 more
semanticscholar +1 more source
Tiludronate and clodronate do not affect bone structure or remodeling kinetics over a 60 day randomized trial [PDF]
, 2018 Background Tiludronate and clodronate are FDA-approved bisphosphonate drug therapies for navicular disease in horses. Although clinical studies have determined their ability to reduce lameness associated with skeletal disorders in horses, data regarding
Gillett, Ashley N. +3 more
core +1 more source
Stem cell research & therapeutics, 2020 As important players in cell-to-cell communication, exosomes (exo) are believed to play a similar role in promoting fracture healing. This study investigated whether exosomes derived from bone marrow mesenchymal stem cells (BMMSC-Exos) could improve ...
Lu Zhang +9 more
semanticscholar +1 more source
A Longitudinal Low Dose μCT Analysis of Bone Healing in Mice: A Pilot Study
Advances in Orthopedics, 2014 Low dose microcomputed tomography (μCT) is a recently matured technique that enables the study of longitudinal bone healing and the testing of experimental treatments for bone repair.
Lu-Zhao Di +9 more
doaj +1 more source
Jurnal Kesehatan Andalas, 2023 Bone injury causes thus, reduced productivity and death in the sufferer. Alternative treatment research was developed to speed up the bone healing process, including autologous treatments such as Platelet-Rich Plasma (PRP).
Noverial Noverial +1 more
doaj +1 more source
Human endothelial-like differentiated precursor cells maintain their endothelial characteristics when cocultured with mesenchymal stem cell and seeded onto human cancellous bone [PDF]
, 2013 Introduction. Cancellous bone is frequently used for filling bone defects in a clinical setting. It provides favourable conditions for regenerative cells such as MSC and early EPC.
Cancellous Bone +7 more
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Comparative histological and histomorphometric results of six biomaterials used in two-stage maxillary sinus augmentation model after 6-month healing [PDF]
, 2018 To evaluate the performances of six different bone substitute materials used as graft in maxillary sinus augmentation by means of histological and histomorphometric analysis of bone biopsies retrieved from human subjects after a 6-month healing period ...
Cristalli, MARIA PAOLA +5 more
core +1 more source