Results 51 to 60 of about 985,336 (268)

Bone Health for Gynaecologists

Medicina
Osteoporosis, the most common bone disorder, profoundly impacts women’s health, especially during postmenopausal phases. Characterised by diminished bone mineral density (BMD), it increases the risk of fractures, affecting mobility, quality of life, and potentially mortality.
Angel Yordanov, Mariela Vasileva-Slaveva, Eva Tsoneva, Stoyan Kostov, Vesselina Yanachkova   +4 more
openaire   +3 more sources

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

Response to High‐Dose Vitamin D Supplementation Is Specific to Imaging Modality and Skeletal Site

JBMR Plus, 2022
High‐dose vitamin D supplementation (4000 or 10,000 IU/d) in vitamin D‐sufficient individuals results in a dose‐dependent decrease in radius and tibia total bone mineral density (Tt.BMD) compared with 400 IU/d.
Lauren A Burt, Leigh Gabel, Emma O Billington, David A Hanley, Steven K Boyd   +4 more
doaj   +1 more source

Safety of Daprodustat for the Treatment of Chronic Kidney Disease Anemia: Final Analysis of a Multicenter Postmarketing Surveillance Study in Japan

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction This final analysis of a multicenter, prospective postmarketing surveillance study evaluated the safety of daprodustat in patients with chronic kidney disease anemia in routine clinical practice in Japan. Methods Patients who initiated daprodustat between September 2020 and July 2022 were registered.
Tadao Akizawa, Kyomi Kanaya, Kiyomi Aizawa, Masanori Onoki, Hirofumi Ozeki, Kazuko Suzuki, Ai Hayashi, Tomohiko Asamura   +7 more
wiley   +1 more source

Participants’ perceived benefits from the GLA:D™ program for individuals living with hip and knee osteoarthritis: a qualitative study

Journal of Patient-Reported Outcomes
Background The Good Life with osteoArthritis: Denmark (GLA:D™), an evidence-based education and exercise program designed for conservative management of knee and hip osteoarthritis (OA), has been shown to benefit participants by reducing pain, improving ...
Ania Kania-Richmond, Lauren A. Beaupre, Geneviève Jessiman-Perreault, Danika Tribo, Jason Martyn, David A. Hart, Jill Robert, Mel Slomp, C. Allyson Jones   +8 more
doaj   +1 more source

Association Between Individualized Education for Kidney Replacement Therapy Modality Selection and Peritoneal Dialysis Initiation: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Peritoneal dialysis (PD) is an established home‐based kidney replacement therapy (KRT), but its uptake remains low in Japan. We evaluated whether individualized education in a dedicated outpatient clinic was associated with the initiation of PD.
Yasuko Ito, Ryuichi Yoshimura, Takaki Yamauchi, Yuta Funakoshi, Hirotaka Sonoda, Seiji Kobayashi, Hiroyuki Terawaki, Takafumi Ito   +7 more
wiley   +1 more source

Proteomics in bone malignancies: from bulk profiling to single-cell and ultra-low-input technologies

Journal of Translational Medicine
Background Bone malignancies, particularly high-grade primary bone sarcomas, remain clinically challenging due to early dissemination, marked heterogeneity, and limited progress in systemic therapies for metastatic or relapsed disease. While genomics and
Jianming Chen, Jiaqiao Luo, Ning Ni, Jinhao Zhang, Lei Jiang, Hongbao Wu, Shenghao Wen, Ninghao Hu, Jiaran Li, Gang Deng, Shuxiang Song, Xiaomeng Shi   +11 more
doaj   +1 more source

Multiple mesenchymal progenitor cell subtypes with distinct functional potential are present within the intimal layer of the hip synovium

BMC Musculoskeletal Disorders, 2019
Background The synovial membrane adjacent to the articular cartilage is home to synovial mesenchymal progenitor cell (sMPC) populations that have the ability to undergo chondrogenesis.
Asmaa Affan, Nedaa Al-Jezani, Pamela Railton, James N. Powell, Roman J. Krawetz   +4 more
doaj   +1 more source

Sclerostin and Its Associations With Bone Metabolism Markers and Sex Hormones in Healthy Community-Dwelling Elderly Individuals and Adolescents

Frontiers in Cell and Developmental Biology, 2020
Sclerostin is an important regulator of bone mass involving Wnt/β-catenin signaling pathway. We aimed to obtain the profile of serum sclerostin level and explore its associations with bone metabolism markers and sex hormones in healthy community-dwelling
Yang Xu, Chao Gao, Jinwei He, Wenqin Gu, Chuntao Yi, Bihua Chen, Qingqing Wang, Feng Tang, Juliang Xu, Hua Yue, Zhenlin Zhang   +10 more
doaj   +1 more source

The human gut microbiome across the life course

FEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero, Basak Bahcivanci, Antonietta Hayhoe, Animesh Acharjee, Ezgi Özkurt   +4 more
wiley   +1 more source