Results 31 to 40 of about 985,336 (268)

Comprehensive network modeling from single cell RNA sequencing of human and mouse reveals well conserved transcription regulation of hematopoiesis

BMC Genomics, 2020
Background Presently, there is no comprehensive analysis of the transcription regulation network in hematopoiesis. Comparison of networks arising from gene co-expression across species can facilitate an understanding of the conservation of functional ...
Shouguo Gao, Zhijie Wu, Xingmin Feng, Sachiko Kajigaya, Xujing Wang, Neal S. Young   +5 more
doaj   +1 more source

Automatic segmentation of trabecular and cortical compartments in HR-pQCT images using an embedding-predicting U-Net and morphological post-processing

Scientific Reports, 2023
High-resolution peripheral quantitative computed tomography (HR-pQCT) is an emerging in vivo imaging modality for quantification of bone microarchitecture.
Nathan J. Neeteson, Bryce A. Besler, Danielle E. Whittier, Steven K. Boyd   +3 more
doaj   +1 more source

Bone health index in the assessment of bone health: The Generation R Study

Bone
Bone Health Index (BHI) has been proposed as a useful instrument for assessing bone health in children. However, its relationship with fracture risk remains unknown. We aimed to investigate whether BHI is associated with bone mineral density (BMD) and prevalent fracture odds in children from the Generation R Study.
Prijatelj, Vid, Grgic, Olja, Uitterlinden, André G., Wolvius, Eppo B., Rivadeneira, Fernando, Medina-Gomez, Carolina   +5 more
openaire   +3 more sources

Provider and Parent Perspectives on Prioritizing the “Asking and Monitoring” Pediatric Cancer Psychosocial Standards of Care

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families (“Standards”) are evidence‐based guidelines for psychosocial care in pediatric oncology. Care related to the three “Asking and Monitoring” Standards—Assessment of Psychosocial Needs, Assessment of Financial Needs, and Monitoring Neurocognitive Problems ...
Julia B. Tager, Natalie Koskela‐Staples, Emily M. Pariseau, Michele Scialla, Kimberly Buff, Lori Wiener, Victoria Sardi Brown, Anne E. Kazak, Kimberly S. Canter   +8 more
wiley   +1 more source

Understanding cartilage protection in OA and injury: a spectrum of possibilities

BMC Musculoskeletal Disorders, 2020
Background Osteoarthritis (OA) is a prevalent musculoskeletal disease resulting in progressive degeneration of the hyaline articular cartilage within synovial joints.
Anand O. Masson, Roman J. Krawetz
doaj   +1 more source

Neuropsychological and Educational Outcomes in Shwachman–Diamond Syndrome—A Report From the North American Shwachman–Diamond Syndrome Registry

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Shwachman–Diamond syndrome (SDS) is a rare autosomal recessive ribosomopathy characterized by bone marrow failure and multisystem involvement, with emerging evidence of associated neurocognitive impairment. Methods We conducted a retrospective study of 240 individuals with biallelic Shwachman–Bodian–Diamond syndrome (SBDS) mutations
Jane Koo, Melissa Gerstle, Leah Cheng, Richard Cooper, Katherine Coyne, Claire Dusa, Naomi E. Joffe, Diana Schwarz, Sarah Steltz, Akiko Shimamura, Kasiani C. Myers, Thea Quinton   +11 more
wiley   +1 more source

Predicting Angiogenesis by Endothelial Progenitor Cells Relying on In-Vitro Function Assays and VEGFR-2 Expression Levels

Biomolecules, 2019
Clinical trials have demonstrated the safety and efficacy of autologous endothelial progenitor cell (EPC) therapy in various diseases. Since EPCs’ functions are influenced by genetic, systemic and environmental factors, the therapeutic potential of
Nadin Sabbah, Tal Tamari, Rina Elimelech, Ofri Doppelt, Utai Rudich, Hadar Zigdon-Giladi   +5 more
doaj   +1 more source

Bone health: biology and nutrition

Current Opinion in Clinical Nutrition & Metabolic Care, 2023
Purpose of review Recent findings in the influence of dietary patterns, dairy products, beverages and microbiota composition and function on bone health are reviewed and discussed. Recent findings Evidence is accumulating on the increased risk of fracture in individuals following a ...
Rizzoli, René, Chevalley, Thierry
openaire   +3 more sources

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens, Evangelia Kiakou, Lieke de Zwart, Maurizio Miano, Eduard J. van Beers, Marc Bierings, Marije Bartels   +6 more
wiley   +1 more source

Bone Health Issues in Sarcoidosis [PDF]

Current Rheumatology Reports, 2011
Sarcoidosis affects the bone directly in only a minority of patients. Nonetheless, bone health should be considered in the management of all patients with sarcoidosis. Deficiency in vitamin D, an important contributor to bone health, has been linked to autoimmune disease incidence.
Sweiss, Nadera J., Lower, Elyse E., Korsten, Peter, Niewold, Timothy B., Favus, Murray J., Baughman, Robert P.   +5 more
openaire   +3 more sources