Results 171 to 180 of about 374,545 (305)

Co-evolution of Calcium Homeostasis and Lactase Persistence: Implications for Treatment of Degenerative Bone Diseases in the 21st Century

, 2017
Ryan J. Glendenning, Aaron J. Williams
openalex   +1 more source

TEAD1 Enhances Exosome Secretion and Promotes Exosome‐Mediated Tissue Regeneration

Advanced Science, EarlyView.
TEAD1 functions as a crucial molecular switch regulating exosome secretion in various cell types. TEAD1 enhances exosome secretion by upregulating key proteins associated with exosome secretion, including RAB11, CD9, and SNAP23. This study reveals a novel role for TEAD1 in regulating exosome secretion and tissue regeneration, particularly in diabetic ...
Yan Pu, Yi Wan, Wenhao Shi, Bin Li, Haiyue Zhang, Jun Wu, Lingling Li, Wenjia Guo, Chen Ding, Wenjun Yang   +9 more
wiley   +1 more source

Bone homeostasis regulation by in vivo generation of osteoclast-derived apoptotic bodies using targeted self-assembly. [PDF]

Nat Commun
Zhang P, Chen D, Fang Y, Li S, Zhou Z, Lu H, Cheng J, Wang H.   +7 more
europepmc   +1 more source

Early effects of ovariectomy on bone health, calcium homeostasis, and antioxidant status in rats [PDF]

Natalia Wawrzyniak, Damla Selvan, Rafsan Cholik, Joanna Suliburska   +3 more
openalex   +1 more source

Regulation of gastric epithelial cell homeostasis by gastrin and bone morphogenetic protein signaling [PDF]

, 2015
Andrea Todisco, Maria Y. Mao, Theresa M. Keeley, Wei Ye, Linda C. Samuelson, Kathryn A. Eaton   +5 more
openalex   +1 more source

PM10 Impairs CD56dim NK Cell Cytotoxicity via FNBP1 Suppression to Exacerbate Rheumatoid Arthritis: Insights from Multimodal Multi‐Omics

Advanced Science, EarlyView.
This study, through multi‐omics approaches and animal models, revealed that air pollutant PM10 exacerbates the progression of rheumatoid arthritis (RA) by suppressing FNBP1 expression and impairing the cytotoxic function of CD56dim NK cells. The “PM10–FNBP1–NK cells” axis provided novel insights into the environmental pathogenesis of RA and suggested ...
Runhan Zhao, Qinyang Zhang, Yu Jiang, Dagang Tang, Xiao Qu, Jun Zhang, Yi Chen, Weixia Duan, Tao Li, Zhengwei Cai, Yanran Huang, Xiaoji Luo   +11 more
wiley   +1 more source

Imbalance of Bone Homeostasis Caused by Nrf2 Deficiency Leads to Bone Loss in OVX Rats. [PDF]

Stem Cells Int
Sun P, Wang Z, Chen S, Chen X, Zhou F, Zhang C, Yang J, Huang Y, Lin Y.   +8 more
europepmc   +1 more source

Gut–Metabolome–Proteome Interactions in Age‐Related Hearing Loss: Insights from Fecal Microbiota Transplantation and Multi‐Omics Analyses

Advanced Science, EarlyView.
Germ‐free (GF) mice receiving fecal microbiota transplantation (FMT) reveal microbiota‐dependent effects on auditory aging. Integrated metagenomic, metabolomic and proteomic profiling maps gut–inner ear network and highlights 5‐hydroxytryptophan (5‐HTP) as a microbiota‐linked metabolic hub in age‐related hearing loss (ARHL).
Ting Yang, Ziwen Gao, Hui Huang, Chanyuan Zhang, Yiquan Tang, Qianhui Qu, Huabin Li, Jing Ke, Zhiji Chen, Menglong Feng, Hu Zhou, Yilai Shu, Wei Yuan   +12 more
wiley   +1 more source

Sulforaphene Mitigates Periodontitis by NRF2-Dependent Regulation of <i>P. gingivalis</i>-Induced Inflammatory Response and Bone Homeostasis. [PDF]

Food Sci Nutr
Yao H, Yu K, Jiang B, Liao Y, Zhao Y, Chen J, Li T, Yin M, Sheng Y, Ye W, Zhao B, Du M, Ji Y.   +12 more
europepmc   +1 more source

The p38α MAPK Function in Osteoprecursors Is Required for Bone Formation and Bone Homeostasis in Adult Mice

, 2014
Eddie Rodríguez-Carballo, Beatriz Gámez, Lara Sedó-Cabezón, Manuela Sánchez‐Feutrie, António Zorzano, María Cristina Manzanares‐Céspedes, José Luís Rosa, Francesc Ventura   +7 more
openalex   +2 more sources