Results 181 to 190 of about 374,545 (305)

Review for "Osteoblast‐Specific Wnt Secretion is Required for Skeletal Homeostasis and Loading‐Induced Bone Formation in Adult Mice"

, 2021

openalex   +1 more source

Inulin‐Based Oral Chemotherapy Modulates Gut Microbiota and Immune Microenvironment through Inhibition of Neutrophil Extracellular Trap Formation for Improving Cancer Therapy

Advanced Science, EarlyView.
Schematic representation of ZIF‐8@OXA@inulin for cancer immunotherapy. Synthesis of ZIF‐8@OXA@inulin. Augmentation of pyroptosis, regulation of gut microbiota, and inhibition of NETs formation by ZIF‐8@OXA@inulin‐mediated comprehensive strategy for antitumor immune response. ABSTRACT Despite the potential of chemoimmunotherapy against colorectal cancer
Zhenhao Li, Jiaqiang Jiang, Yuping Zhou, Xinyuan Mao, Haotian Wen, Zhian Chen, Yutong Wang, Cong Huang, Yanfeng Hu   +8 more
wiley   +1 more source

Spermidine-encapsulated chondroitin sulfate methacryloyl hydrogel delivery system for remodeling bone homeostasis in rheumatoid arthritis. [PDF]

Mater Today Bio
Wang X, He J, Hong Y, Jie L, Wu B, Shen J, Zhou G, Wang Q.   +7 more
europepmc   +1 more source

Dimorphic effects of Notch signaling in bone homeostasis

, 2008
Feyza Engin, Zhenqiang Yao, Tao Yang, Guang Zhou, Terry Bertin, Ming Jiang, Yuqing Chen, Lisa Wang, Hui Zheng, Richard E. Sutton, Brendan F. Boyce, Brendan Lee   +11 more
openalex   +2 more sources

Single‐Cell Profiling Across Immune Tissues and Organs Reveals Immunosenescence Signatures in Male Rhesus Monkeys

Advanced Science, EarlyView.
Single‐cell profiling across bone marrow, spleen, mesenteric lymph, and blood in rhesus monkeys reveals organ Immunosenescence. GZMB rises with age, particularly in cytotoxic and terminally exhausted CD8+ T cells, and BHLHE40 emerges as a key transcription factor enriched across multiple CD8+ subsets, regulating pro‐inflammatory and exhaustion‐related ...
Shengnan Wang, Zhengna Zhu, Hongju Yang, Yaping Yan, Luyao Ran, Naixue Yang, Yichao Wang, Li Wu, Bing Bai, Weizhi Ji, Wei Si   +10 more
wiley   +1 more source

Black phosphorus-based photothermal-responsive hydrogel enhanced osteoporotic bone injury regeneration by alleviating oxidative stress and remodeling bone homeostasis. [PDF]

J Nanobiotechnology
Zhang Y, Qi G, Zhang L, Chen Y, Fu J, Yang L, Ke Z, Ma Y, Zhao W, Zhao Y, Ye L, Jiang M, Cai L, Zhang Y, Liu X, Li X, Wu P, Wu M, Wang Z.   +18 more
europepmc   +1 more source

Ufmylation‐Deficient DDRGK1 Ameliorates Obesity by Inhibiting FASN‐Mediated Adipocyte Lipogenesis

Advanced Science, EarlyView.
DDRGK1 regulates de novo lipogenesis via stabilization of fatty acid synthase (FASN). DDRGK1‐mediated UFMylation of FASN prevents its ubiquitin–proteasomal degradation. Reduced DDRGK1 expression or mutation at the key UFMylation site enhances FASN degradation and suppresses fatty acid synthesis (FAS), resulting in smaller adipocytes and improved ...
Yin Li, Tangjun Zhou, Xiao Yang, Kewei Rong, Xiankun Cao, Lei Shi, Xin Wang, Hongjin Wan, Lei Cui, Kexin Liu, Tong Xing, Hang Zhang, Chen Zhao, Tingxian Guo, Peixiang Ma, Jie Zhao, An Qin   +16 more
wiley   +1 more source

From neuromodulation to bone homeostasis: therapeutic targets of nerve growth factor in skeletal diseases. [PDF]

Front Pharmacol
Chen K, Chen L, Ma Y, Chen S, Liu J, Zhou H, Chen Y, Liu G.   +7 more
europepmc   +1 more source

Modulating Integrin and Growth Factor Signaling With Peptides: Strategies to Synergistically Enhance Bone Tissue Regeneration

Advanced Science, EarlyView.
It has been demonstrated that, in the bone extracellular matrix (ECM), integrins and growth factor receptors (GFRs) engage in synergistic signaling to guide bone healing and regeneration. This review provides a comprehensive overview of current strategies using ECM‐derived peptides to recreate the cellular microenvironment and harness synergistic ...
Lluís Oliver‐Cervelló, Elisabetta Ada Cavalcanti‐Adam, Carlos Mas‐Moruno   +2 more
wiley   +1 more source

Autophagy in osteoblasts is involved in mineralization and bone homeostasis [PDF]

, 2014
Marie Nollet, Sabine Santucci‐Darmanin, Véronique Breuil, Rasha Al-Sahlanee, Chantal Cros, Majlinda Topi, David Momier, Michel Samson, Sophie Pagnotta, Laurence Cailleteau, Séverine Battaglia, Delphine Farlay, Romain Dacquin, Nicolas Barois, Pierre Jurdic, Georges Boivin, Dominique Heymann, Frank Lafont, Shi Shou Lu, David W. Dempster, Georges F. Carle, Valérie Pierrefite‐Carle   +21 more
openalex   +1 more source