Results 1 to 10 of about 2,390,783 (219)

Overrepresentation of Germline Immune-Related Gene Variants in Patients with Acquired Bone Marrow Failure. [PDF]

J Clin Immunol
Pinc Z, Kundrat D, Kaisrlikova M, Hrustincova A, Vanikova S, Trsova I, Vesela J, Vostry M, Pejsova B, Ransdorfova S, Slamova L, Prochazka T, Lysak D, Jonasova A, Markova MS, Cermak J, Belickova M, Votavova H.   +17 more
europepmc   +3 more sources

Cerebrospinal fluid regulates skull bone marrow niches via direct access through dural channels

Nature Neuroscience, 2022
It remains unclear how immune cells from skull bone marrow niches are recruited to the meninges. Here we report that cerebrospinal fluid (CSF) accesses skull bone marrow via dura–skull channels, and CSF proteins signal onto diverse cell types within the ...
J. Mazzitelli, Leon C. D. Smyth, Kevin A Cross, Taitea Dykstra, Jerry Sun, Siling Du, Tornike Mamuladze, Igor Smirnov, Justin Rustenhoven, J. Kipnis   +9 more
semanticscholar   +1 more source

Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma

Science, 2021
Getting around the blood–brain barrier The meninges comprise three membranes that surround and protect the central nervous system (CNS). Recent studies have noted the existence of myeloid cells resident there, but little is known about their ontogeny and
A. Cugurra, Tornike Mamuladze, Justin Rustenhoven, Taitea Dykstra, Giorgi Beroshvili, Zev J. Greenberg, Wendy Baker, Zachary Papadopoulos, Antoine Drieu, Susan M. Blackburn, M. Kanamori, S. Brioschi, Jasmin Herz, Laura G. Schuettpelz, M. Colonna, Igor Smirnov, J. Kipnis   +16 more
semanticscholar   +1 more source

Impact of donor marrow cellularity on outcome of allogeneic stem cell transplantation

Transplantation Reports, 2023
Background: Outcomes of allogeneic hematopoietic stem cell transplant (HSCT) are affected by a number of donor and patient related factors like extent of human leucocyte antigen mismatch, age, source of stem cells, female donor to male recipient and stem
Memoona Khan, Ghassan Umair Shamshad, Qamar un Nisa Chaudhry, Raheel Iftikhar, Nighat Shahbaz, Mehreen Ali Khan, Farwa Raza, Haider Nisar, Mehwish Gilani   +8 more
doaj   +1 more source

Case report: A novel mutation in RTEL1 gene in dyskeratosis congenita

Frontiers in Oncology, 2023
Dyskeratosis congenita (DKC), also known as Zinsser–Cole–Engman syndrome, is a telomeropathy typically presenting as a triad of leukoplakia, nail dystrophy, and reticular hyperpigmentation.
Haider Nisar, Memoona Khan, Qamar Un Nisa Chaudhry, Qamar Un Nisa Chaudhry, Raheel Iftikhar, Tariq Ghafoor   +5 more
doaj   +1 more source

COMPLICATIONS IN ABO-INCOMPATIBLE HEMATOPOIETIC STEM CELL TRANSPLANT IN PAKISTAN

Gomal Journal of Medical Sciences, 2021
Background: Hematopoietic stem cell transplantation (HSCT) is therapeutic option for many blood diseases. It has increased risk of complications with incompatible pair.
Mussawair Hussain, Imran Ullah, Nighat Shahbaz, Qamar Un Nisa Chaudhry, Mehreen Ali Khan, Tariq Azam Khattak   +5 more
doaj   +1 more source

Correction to: Decitabine plus CLAG chemotherapy as a bridge to haploidentical transplantation in the setting of acute myeloid leukemia relapse after HLA-matched sibling transplantation: a case report

BMC Cancer, 2019
Following publication of the original article [1], the authors reported that the incorrect Fig. 2A was published in the article. The recovery times required to achieve a normal neutrophil count was omitted. The corrected Fig.
Mengqi Jin, Yongxian Hu, Wenjun Wu, Yi Luo, Yamin Tan, Jian Yu, Aiyun Jin, Luxin Yang, He Huang, Guoqing Wei   +9 more
doaj   +1 more source

Single cell transcriptomics identifies a unique adipose lineage cell population that regulates bone marrow environment

eLife, 2020
Bone marrow mesenchymal lineage cells are a heterogeneous cell population involved in bone homeostasis and diseases such as osteoporosis. While it is long postulated that they originate from mesenchymal stem cells, the true identity of progenitors and ...
L. Zhong, L. Yao, R. Tower, Yulong Wei, Zhen Miao, Jihwan Park, Rojesh Shrestha, Luqiang Wang, Wei Yu, Nicholas Holdreith, Xiaobin Huang, Yejia Zhang, W. Tong, Y. Gong, Jaimo Ahn, K. Suszták, Nathanial Dyment, Mingyao Li, Fanxin Long, Chider Chen, P. Seale, L. Qin   +21 more
semanticscholar   +1 more source

Economic analysis of allogeneic hematopoietic stem cell transplantation in the Bone Marrow Transplant Center of Tunisia

Journal of Market Access & Health Policy, 2023
Introduction: New procedures and diagnostic tests in hematopoietic stem cell transplantation (HSCT) are associated with a significant increase in costs.
Leila Achour, Chema Drira, Mohamed Zied Sboui, Ikram Fazaa, Mohamed Ali Soussi, Senda Hammami, Tarek Ben Othman, Myriam Razgallah Khrouf   +7 more
doaj   +1 more source

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

Nature Network Boston, 2012
Tumor-derived exosomes are emerging mediators of tumorigenesis. We explored the function of melanoma-derived exosomes in the formation of primary tumors and metastases in mice and human subjects.
H. Peinado, M. Alečković, S. Lavotshkin, Irina R Matei, B. Costa-Silva, G. Moreno-Bueno, M. Hergueta-Redondo, Caitlin Williams, G. García‐Santos, Cyrus M. Ghajar, Ayuko Nitadori-Hoshino, Caitlin E. Hoffman, K. Badal, B. Garcia, M. Callahan, Jianda Yuan, V. Martins, J. Skog, R. Kaplan, M. Brady, J. Wolchok, P. Chapman, Yibin Kang, J. Bromberg, D. Lyden   +24 more
semanticscholar   +1 more source