Results 1 to 10 of about 2,653,972 (365)
Bone marrow hematopoiesis drives multiple sclerosis progression
Cell, 2022 Multiple sclerosis (MS) is a T cell-mediated autoimmune disease of the central nervous system (CNS). Bone marrow hematopoietic stem and progenitor cells (HSPCs) rapidly sense immune activation, yet their potential interplay with autoreactive T cells in ...
Kaibin Shi, Qiang Liu, Fu-Dong Shi
exaly +2 more sources
Mesenchymal and haematopoietic stem cells form a unique bone marrow niche
Nature, 2010 The cellular constituents forming the haematopoietic stem cell (HSC) niche in the bone marrow are unclear, with studies implicating osteoblasts, endothelial and perivascular cells.
Grigori Enikolopov +2 more
exaly +2 more sources
Skull and vertebral bone marrow are myeloid cell reservoirs for the meninges and CNS parenchyma
Science, 2021 Getting around the blood–brain barrier The meninges comprise three membranes that surround and protect the central nervous system (CNS). Recent studies have noted the existence of myeloid cells resident there, but little is known about their ontogeny and
A. Cugurra +16 more
semanticscholar +1 more source
Cerebrospinal fluid regulates skull bone marrow niches via direct access through dural channels
Nature Neuroscience, 2022 It remains unclear how immune cells from skull bone marrow niches are recruited to the meninges. Here we report that cerebrospinal fluid (CSF) accesses skull bone marrow via dura–skull channels, and CSF proteins signal onto diverse cell types within the ...
Jose A. Mazzitelli +9 more
semanticscholar +1 more source
Cell Stem Cell, 2022 A fundamental question in bone biology concerns the contributions of skeletal stem/progenitor cells (SSCs) in the bone marrow versus the periosteum to bone repair. We found that SSCs in adult bone marrow can be identified based on Leprcre and Adiponectin-
Elise C. Jeffery +4 more
semanticscholar +1 more source
Impact of donor marrow cellularity on outcome of allogeneic stem cell transplantation
Transplantation Reports, 2023 Background: Outcomes of allogeneic hematopoietic stem cell transplant (HSCT) are affected by a number of donor and patient related factors like extent of human leucocyte antigen mismatch, age, source of stem cells, female donor to male recipient and stem
Memoona Khan +8 more
doaj +1 more source
Blood, 2021 Artificial intelligence (AI) and machine learning algorithms are changing many facets of our lives and have great potential for disease diagnosis. In this Plenary Paper, Matek et al describe training a convolutional neural network model using 171 374 ...
C. Matek +4 more
semanticscholar +1 more source
Case report: A novel mutation in RTEL1 gene in dyskeratosis congenita
Frontiers in Oncology, 2023 Dyskeratosis congenita (DKC), also known as Zinsser–Cole–Engman syndrome, is a telomeropathy typically presenting as a triad of leukoplakia, nail dystrophy, and reticular hyperpigmentation.
Haider Nisar +5 more
doaj +1 more source
BMC Cancer, 2019 Following publication of the original article [1], the authors reported that the incorrect Fig. 2A was published in the article. The recovery times required to achieve a normal neutrophil count was omitted. The corrected Fig.
Mengqi Jin +9 more
doaj +1 more source
COMPLICATIONS IN ABO-INCOMPATIBLE HEMATOPOIETIC STEM CELL TRANSPLANT IN PAKISTAN
Gomal Journal of Medical Sciences, 2021 Background: Hematopoietic stem cell transplantation (HSCT) is therapeutic option for many blood diseases. It has increased risk of complications with incompatible pair.
Mussawair Hussain +5 more
doaj +1 more source