Results 11 to 20 of about 2,378,510 (365)

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

Nature Network Boston, 2012
Tumor-derived exosomes are emerging mediators of tumorigenesis. We explored the function of melanoma-derived exosomes in the formation of primary tumors and metastases in mice and human subjects.
H. Peinado, M. Alečković, S. Lavotshkin, Irina R Matei, B. Costa-Silva, G. Moreno-Bueno, M. Hergueta-Redondo, Caitlin Williams, G. García‐Santos, Cyrus M. Ghajar, Ayuko Nitadori-Hoshino, Caitlin E. Hoffman, K. Badal, B. Garcia, M. Callahan, Jianda Yuan, V. Martins, J. Skog, R. Kaplan, M. Brady, J. Wolchok, P. Chapman, Yibin Kang, J. Bromberg, D. Lyden   +24 more
semanticscholar   +1 more source

Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor

Journal of Experimental Medicine, 1992
Antigen-presenting, major histocompatibility complex (MHC) class II- rich dendritic cells are known to arise from bone marrow. However, marrow lacks mature dendritic cells, and substantial numbers of proliferating less-mature cells have yet to be ...
K. Inaba, M. Inaba, N. Romani, Hideki Aya, Masashi Deguchi, S. Ikehara, S. Muramatsu, Ralph M. Steinmanll   +7 more
semanticscholar   +1 more source

Bone Vasculature and Bone Marrow Vascular Niches in Health and Disease

Journal of Bone and Mineral Research, 2020
Bone vasculature and bone marrow vascular niches supply oxygen, nutrients, and secrete angiocrine factors required for the survival, maintenance, and self‐renewal of stem and progenitor cells.
Junyu Chen, M. Hendriks, A. Chatzis, Saravana K. Ramasamy, Anjali P. Kusumbe   +4 more
semanticscholar   +1 more source

Bone-Marrow [PDF]

The American Journal of the Medical Sciences, 1898
n ...
openaire   +1 more source

Type and frequency of hemoglobinopathies, diagnosed in the area of Karachi, in Pakistan

Cogent Medicine, 2016
Hemoglobinopathies are one of the major problems in Pakistan. A retrospective analysis of blood samples of 2731 patients from 2010 to 2014 was done at National Institute of Blood Disease & Bone Marrow Transplantation for the workup of anemia or other ...
Shaista Shabbir, Muhammad Nadeem, Abdul Sattar, Iffat Ara, Saqib Ansari, Tassneem Farzana, Mehwish Taj, Munira Borhany, Saima Manzir, Uzma Zaidi, Jawad Hassan, Arshi Naz, Tahir Shamsi   +12 more
doaj   +1 more source

Vaccine-induced thrombotic thrombocytopenia (VITT): first report from India

Thrombosis Journal, 2022
Background Vaccine-induced thrombotic thrombocytopenia (VITT) is a rare but devastating adverse event following adenoviral vector-based vaccinations for COVID-19, resulting in thrombosis, especially of the cerebral and splanchnic vasculature. Despite the
Christy V. John, Rajesh Kumar, Anil Kumar Sivan, Sangeetha Jithin, Rojin Abraham, Chepsy C. Philip   +5 more
doaj   +1 more source

Bone Marrow Necrosis [PDF]

Cancer, 1980
Extensive bone marrow necrosis is an unusual histologic finding most commonly identified after autopsy. We describe a patient with poorly differentiated lymphocytic lymphoma who manifested pancytopenia and marrow necrosis. Bone marrow scanning with 99mTc-sulfur-minicolloid provided a noninvasive means to assess the extent of marrow damage.
Merrill S. Kies, Ronald N. Rubin, John D. Cowan, Lizardo Cerezo   +3 more
openaire   +3 more sources

Combined single-cell and spatial transcriptomics reveals the molecular, cellular and spatial bone marrow niche organization

Nature Cell Biology, 2019
The bone marrow constitutes the primary site for life-long blood production and skeletal regeneration. However, its cellular and spatial organization remains controversial.
Chiara Baccin, Jude Al-Sabah, Lars Velten, Patrick M. Helbling, F. Grünschläger, Pablo Hernández-Malmierca, C. Nombela-Arrieta, L. Steinmetz, A. Trumpp, S. Haas   +9 more
semanticscholar   +1 more source

Treatment of bone marrow lesions (bone marrow edema) [PDF]

BoneKEy Reports, 2015
Bone marrow lesions (BMLs) or using older terminology 'Bone marrow edema' is characterised by excessive water signals in the marrow space on magnetic resonance imaging or ultrasound; BMLs constitute a central component of a wide variety of inflammatory and non-inflammatory rheumatologic conditions affecting the musculoskeletal system: BMLs are not only
openaire   +3 more sources

Karyotype abnormalities and their clinical significance in a group of chronic myeloid leukemia patients treated with hematopoietic stem cell transplantation

São Paulo Medical Journal
CONTEXT AND OBJECTIVE: Following hematopoietic stem cell transplantation (HSCT), karyotyping is a valuable tool for monitoring engraftment and disease status.
Luize Otero, Maria Helena Ornellas, Alexandre Mello de Azevedo, Rita de Cássia Tavares, Virgínia Pires, Eliana Abdelhay, Luis Fernando Bouzas, Teresa de Souza Fernandez   +7 more
doaj   +1 more source