Results 241 to 250 of about 2,858,038 (359)

The Rise of Mechanobiology for Advanced Cell Engineering and Manufacturing

Advanced Materials, EarlyView.
With the growing demand for cell‐based therapies, efficient cellular engineering is crucial. This review calls for greater recognition of mechanobiology principles applied through advanced biomaterial designs, mechanical confinement, and highlights recent advances using micro/nanotechnologies to enhance cell manufacturing.
Huan Ting Ong, M Sriram, Hepi Hari Susapto, Yixuan Li, Yuan Jiang, Nicolas H. Voelcker, Jennifer L. Young, Andrew W. Holle, Roey Elnathan   +8 more
wiley   +1 more source

CXCR Family and Hematologic Malignancies in the Bone Marrow Microenvironment. [PDF]

Biomolecules
Liu Y, Tang H.
europepmc   +1 more source

Mobilized bone marrow cells repair the infarcted heart, improving function and survival

Proceedings of the National Academy of Sciences of the United States of America, 2001
D. Orlic, J. Kajstura, S. Chimenti, Federica Limana, Igor Jakoniuk, F. Quaini, B. Nadal-Ginard, D. Bodine, A. Leri, P. Anversa   +9 more
semanticscholar   +1 more source

Designing the Next Generation of Biomaterials through Nanoengineering

Advanced Materials, EarlyView.
Nanoengineering enables precise control over biomaterial interactions with living systems by tuning surface energy, defects, porosity, and crystallinity. This review highlights how these nanoscale design parameters drive advances in regenerative medicine, drug delivery, bioprinting, biosensing, and bioimaging, while outlining key translational ...
Ryan Davis Jr., Ishaan Duggal, Nicholas A. Peppas, Akhilesh K. Gaharwar   +3 more
wiley   +1 more source

Organic AIE Nanoradiosensitizer Potentiates X‐Ray Triggered Continuous Reactive Oxygen Species Generation for Potent Cancer Radioimmunotherapy

Advanced Materials, EarlyView.
Herein, a glutathione‐responsive system (named THN) is prepared for X‐ray‐triggered sustained ROS generation for efficient antitumor immunotherapy. The double‐promoting ROS generation of THN induced massive immunogenic cancer cell death and polarized M2 macrophages into the M1 phenotype for enhanced antitumor immunotherapy.
Qingyong Xu, Minmin Zhang, Qinqin Huang, Song Gao, Sitong Chu, Qi Li, Wanyao Chen, Xinglong Zhang, Tianfu Zhang, Ben Zhong Tang, Shipeng Ning   +10 more
wiley   +1 more source

Rethinking bone marrow biopsy: is PET/CT enough for staging low-grade follicular lymphomas? [PDF]

Ann Hematol
Chen YY, Wang JJ, Zhong WH, Guo JR, Qiu YY, Liu TX, Zheng H, Chen SL, Liao SQ, Zhao RZ, Shi GQ, Tang TL, Lin YP, Huang C, Chen JH, Liu TB, Zhang YJ, Yang Y.   +17 more
europepmc   +1 more source

MUTE‐Seq: An Ultrasensitive Method for Detecting Low‐Frequency Mutations in cfDNA With Engineered Advanced‐Fidelity FnCas9

Advanced Materials, EarlyView.
An advanced‐fidelity CRISPR nuclease, FnCas9‐AF2, is rationally engineered to discriminate single‐base mismatches with unprecedented level precision. Integrated into the MUTE‐Seq workflow, FnCas9‐AF2 depletes wild‐type cell‐free DNA, thereby exposing rare tumor‐derived mutant DNA (a molecular “needle in a haystack”).
Sunghyeok Ye, Jin‐Soo Kim, Myungshin Kim, Ki‐Yeon Kim, Yoon‐Ho Won, Taegun Park, Sungjae An, Haerin Jeong, Hee‐Joon Chung, In Seon Lee, Myoung‐Hee Kang, Chan Young Kang, Mi Young Kim, Jae Ho Chung, Jeong‐An Gim, Woochang Hwang, Yonggoo Kim, Song Cheol Kim, Sungho Lee, Junho K Hur, Junseok W Hur   +20 more
wiley   +1 more source

TNFα stimulates osteoclastogenesis and expression of CX3CL1 in non-adherent bone marrow cells. [PDF]

Biochem Biophys Rep
Otsuka Y, Hattori N, Aoki H, Toriuchi K, Inoue Y, Hayashi H, Kuroyanagi G, Kawaguchi Y, Waguri-Nagaya Y, Aoyama M.   +9 more
europepmc   +1 more source

Leptin-receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow.

Cell Stem Cell, 2014
B. Zhou, R. Yue, M. Murphy, James G. Peyer, S. Morrison   +4 more
semanticscholar   +1 more source