Results 241 to 250 of about 687,155 (340)

Enhancing Osteogenesis through Bio‐Inspired Recombinant Coral Protein Galaxin by Targeting Mitochondrial Metabolism and ATP Production

Advanced Science, EarlyView.
The study highlights the potential of recombinant galaxin (a coral protein) as a novel and effective biomaterial for bone regeneration. It binds to ATP synthase subunit β (ATP5B) in mouse pre‐osteoblasts, thereby causing increased ATP production and mitochondrial activity.
Fei Yu, Xing Zhao, Ting Jiang, Ningjuan Ouyang, Peilin Li, Wei Yang, Zhihe Zhao   +6 more
wiley   +1 more source

Antibiotic Resistance to <i>Pseudomonas Aeruginosa</i> in the Saliva of Candidates of Bone Marrow Transplantation. [PDF]

J Dent (Shiraz)
Zahed M, Safvat M, Bazargani A, Ghapanchi J, Ranjbar Z.   +4 more
europepmc   +1 more source

Treatment of pediatric acute lymphoblastic leukemia in India on BFM 95 protocol backbone with relevant modifications and minimal residual disease application - Doable and effective

Pediatric Hematology Oncology Journal, 2022
Dhwanee Thakkar, K. Upasana, Sunisha Arora, Ritu Chadha, D.S. Udayakumar, Bhawna Jha, Anjali Yadav, Neha Rastogi, Shalini Goel, Renu Saxena, Satya Prakash Yadav   +10 more
doaj  

Lactylation‐Driven NUPR1 Promotes Immunosuppression of Tumor‐Infiltrating Macrophages in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Cai et al. report that tumor‐derived lactate induces NUPR1 expression via H3K18 lactylation, which can promote the pro‐tumor M2 macrophage polarization through ERK and JNK signaling pathways. Treatment with NUPR1 selective inhibitor sensitizes synergizes with anti‐PD‐1 therapy in murine preclinical models.
Jialiang Cai, Peiling Zhang, Yufan Cai, Guiqi Zhu, Shiping Chen, Lina Song, Junxian Du, Biao Wang, Weixing Dai, Jian Zhou, Jia Fan, Yiyi Yu, Zhi Dai   +12 more
wiley   +1 more source

Microfluidic isolation and release of live disseminated breast tumor cells in bone marrow. [PDF]

PLoS One
Le MN, Chen D, Smith KA, Tran DD, Fan ZH.   +4 more
europepmc   +1 more source

The triple A (AAA) model globally recapitulates adverse outcomes in essential thrombocythemia

Blood Cancer Journal
Luca Tosoni, Gian Luca Morelli, Gaia Tomadini, Davide Lazzarotto, Carla Filì, Erica Simeone, Maria Elena Zannier, Chiara Callegari, Matteo Fanin, Giulia Battaglia, Melissa Bergnach, Daniela Damiani, Renato Fanin, Mario Tiribelli   +13 more
doaj   +1 more source

Citrullination of NF‐κB p65 by PAD2 as a Novel Therapeutic Target for Modulating Macrophage Polarization in Acute Lung Injury

Advanced Science, EarlyView.
Peptidyl arginine deiminase 2 (PAD2) plays a key role in regulating macrophage function in Pseudomonas aeruginosa‐induced acute lung injury (ALI). Using single‐cell RNA sequencing and proteomics, a new PAD2‐catalyzed citrullination site on NF‐κB p65 (171 Arginine), modulating macrophage polarization is identified.
Xin Yu, Yujing Song, Tao Dong, Wenlu Ouyang, Chao Quan, Liujiazi Shao, Leonard Barasa, Paul R. Thompson, Mao Zhang, Jianjie Ma, Katsuo Kurabayashi, Yongqing Li   +11 more
wiley   +1 more source

Symptomatic bone marrow metastasis in triple-negative breast cancer: a case report and literature review. [PDF]

Front Oncol
Zheng C, Dai J, Wang Y, Zheng D, Lin R, Zheng Z.   +5 more
europepmc   +1 more source

Histochemical Study on the Phosphatase Distribution in Rabbit Bone Marrow Cells

, 1953
Tom Mori
openalex   +2 more sources

PPY‐Induced iCAFs Cultivate an Immunosuppressive Microenvironment in Pancreatic Cancer

Advanced Science, EarlyView.
Pancreatic ductal adenocarcinoma features abundant stromal components that hinder therapy efficacy. Single‐cell RNA sequencing analysis combined with experiments identified PPY, a gastrointestinal hormone, as a novel inducer of immunosuppressive iCAFs. Mechanistic studies revealed that PPY activates the non‐canonical NF‐κB pathway via EGFR.
Mengdie Cao, Wang Peng, Bin Cheng, Ronghua Wang, Wei Chen, Luyao Liu, Hai Huang, Shiru Chen, Haochen Cui, JingWen Liang, Qiaodan Zhou, Si Xiong, Shuya Bai, Luoxia Liu, Yuchong Zhao   +14 more
wiley   +1 more source