Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET
Nature Network Boston, 2012 Tumor-derived exosomes are emerging mediators of tumorigenesis. We explored the function of melanoma-derived exosomes in the formation of primary tumors and metastases in mice and human subjects.
H. Peinado +24 more
semanticscholar +1 more source
The relationship between adiposity, bone density and microarchitecture is maintained in young women irrespective of diabetes status [PDF]
, 2017 Background: The relationship between bone health and adiposity and how it may be affected in people with chronic metabolic conditions is complex. Methods: 17 women with Type 1 diabetes mellitus (T1DM) and 9 age-matched healthy women with a median ...
Abdalrahaman, N. +7 more
core +1 more source
Journal of Experimental Medicine, 1992 Antigen-presenting, major histocompatibility complex (MHC) class II- rich dendritic cells are known to arise from bone marrow. However, marrow lacks mature dendritic cells, and substantial numbers of proliferating less-mature cells have yet to be ...
K. Inaba +7 more
semanticscholar +1 more source
Bone Vasculature and Bone Marrow Vascular Niches in Health and Disease
Journal of Bone and Mineral Research, 2020 Bone vasculature and bone marrow vascular niches supply oxygen, nutrients, and secrete angiocrine factors required for the survival, maintenance, and self‐renewal of stem and progenitor cells.
Junyu Chen +4 more
semanticscholar +1 more source
Perioperative donor bone marrow infusion augments chimerism in heart and lung transplant recipients [PDF]
, 1995 Background.: We and others have demonstrated that a low level of donor cell chimerism was present for years after transplantation in tissues and peripheral blood of heart and lung recipients; it was associated, in the latter, with a lower incidence of ...
Abdul S. Rao +34 more
core +1 more source
Experimental study and practice on the detection of vegetative planktons in the bone marrow of the drowned dead body [PDF]
, 1959 Experiment on the animals proved that in the case of the death by drowning planktons always immigrate into the bone marrow and some kinds of them can be detected in the bone marrow even after a long period of time, suggesting that the detection of these ...
Kamimura, Osamu +3 more
core +1 more source
The Differentiation Balance of Bone Marrow Mesenchymal Stem Cells Is Crucial to Hematopoiesis. [PDF]
, 2018 Bone marrow mesenchymal stem cells (BMSCs), the important component and regulator of bone marrow microenvironment, give rise to hematopoietic-supporting stromal cells and form hematopoietic niches for hematopoietic stem cells (HSCs).
Li, Shengwen Calvin +6 more
core +2 more sources
The vascular bone marrow niche influences outcome in chronic myeloid leukemia via the E-selectin - SCL/TAL1-CD44 axis. [PDF]
, 2020 The endosteal bone marrow niche and vascular endothelial cells provide sanctuaries for leukemic cells. In murine chronic myeloid leukemia (CML) CD44 on leukemia cells and E-selectin on bone marrow endothelium are essential mediators for the engraftment ...
Aggoune, D. +17 more
core +2 more sources
MRI in multiple myeloma : a pictorial review of diagnostic and post-treatment findings [PDF]
, 2016 Magnetic resonance imaging (MRI) is increasingly being used in the diagnostic work-up of patients with multiple myeloma. Since 2014, MRI findings are included in the new diagnostic criteria proposed by the International Myeloma Working Group.
A Baur +51 more
core +2 more sources