Results 101 to 110 of about 960,390 (294)

Matrix-Associated Chondroplasty: A Novel Platelet-Rich Plasma and Concentrated Nucleated Bone Marrow Cell–Enhanced Cartilage Restoration Technique

open access: yesArthroscopy Techniques, 2014
Bone marrow stimulation techniques such as microfracture for the treatment of articular cartilage defects so far solely reproduce mechanically inferior fibrous cartilage tissue, which might result in unsatisfactory clinical results at midterm.
Matthias R. Steinwachs, M.D.   +3 more
doaj   +1 more source

To Evaluate the Role of Bone Marrow Aspiration and Bone Marrow Biopsy in Pancytopenia

open access: yesJOURNAL OF CLINICAL AND DIAGNOSTIC RESEARCH, 2014
Pancytopenia is not a disease entity but a triad of findings that may result from various disease processes, primarily or secondarily involving the bone marrow. Bone marrow aspiration and biopsy evaluation along with good clinical correlation is of utmost importance to evaluate the causes of pancytopenia and planning further investigations.The present ...
Melina Desalphine   +3 more
openaire   +3 more sources

Augmentation of Arthroscopic Rotator Cuff Repair Using Enthesis Interpositional Allograft and Minced Autologous Subacromial Bursa

open access: yesArthroscopy Techniques, EarlyView.
Abstract Multiple strategies for rotator cuff augmentation have been developed to promote tendon healing and decrease retear rates. Previously published techniques and clinical studies have primarily emphasized biologic adjuncts intended to alter the local healing environment at the repair site or structural reinforcement with grafts.
Matthew D. Smith   +2 more
wiley   +1 more source

Tailoring drug‐to‐lipid ratio in redox‐responsive lipid‐mimetic prodrug liposomes for superior cabazitaxel delivery and antitumor efficacy

open access: yesBMEMat, EarlyView.
Redox‐responsive lipid‐mimetic prodrug liposomes with high drug‐to‐lipid ratios enhance cabazitaxel delivery, prolong circulation, and enable tumor‐selective drug release for superior antitumor efficacy and safety. Abstract Liposomes represent one of the most extensively investigated nanocarriers in drug delivery.
Shengyao Xu   +16 more
wiley   +1 more source

Avaliação de centrifugado osteogênico de medula óssea na consolidação de fratura em coelhos Evaluation of centrifuged osteogenic bone marrow in fracture consolidation in rabbits

open access: yesActa Ortopédica Brasileira, 2010
OBJETIVO: Avaliar a eficácia de um centrifugado osteogênico de medula óssea em estimular a consolidação de osteotomias da fíbula em coelhos. MÉTODOS: Foram utilizados dez coelhos machos adultos da raça Nova Zelândia albino.
Carlos Eduardo Sanches Vaz   +2 more
doaj   +1 more source

Role of Percutaneous Bone Marrow Aspirate Injection in Delayed Union of Femur and Tibia Diaphyseal Fractures

open access: yesJournal of Rawalpindi Medical College, 2018
Background: To compare the results of percutaneous bone marrow aspirate injection with autologous bone grafting in the treatment of delayed union of femur and tibia diaphyseal fractures using Union Scale Score.
Rizwan H. Malik et al.,
doaj  

Bridging the translational gap in clinical nanomedicine: From rational design to clinical reality

open access: yesBMEMat, EarlyView.
Nanotechnology offers a multi‐faceted approach to modern healthcare, encompassing high‐sensitivity diagnostic imaging, innovative vaccine delivery, and targeted therapeutics. This review explores how these nanomedicine applications address critical challenges in cancer recurrence and the treatment of neurologic and respiratory diseases to combat rising
Ahmed H. Ghonaim   +9 more
wiley   +1 more source

Lipid droplet profiling during neutrophil differentiation by stimulated Raman scattering microscopy

open access: yesBiotechnology Progress, EarlyView.
Abstract Lipid droplets (LDs) are dynamic organelles that serve as metabolic hubs and emerging regulators of immune cell fate. Although LDs have been implicated in immune regulation, how LD metabolism is remodeled during neutrophil differentiation and how stage‐specific LD dynamics shape mature neutrophil function remain poorly defined.
Ting‐Jung Sung   +5 more
wiley   +1 more source

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović   +11 more
wiley   +1 more source

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