Results 71 to 80 of about 960,390 (294)

Evaluation of single and multiple use of bone marrow aspirate in management of tibia fractures of Nigerian indigenous dogs

Journal of Applied Animal Research, 2018
Osteogenic potential of autologous bone marrow aspirates was evaluated on transverse tibia fractures of 12 Nigeria indigenous dogs presented to University of Nigeria Veterinary Teaching Hospital, Nsukka (UNVTH).
Theophilus Okafor Nnaji, Innocent Nwaogu, Nnenna Ugwu, Chioma Onyenekwe   +3 more
doaj   +1 more source

An Improved Technic of Bone Marrow Aspiration [PDF]

Blood, 1951
Abstract 1. The original Arinkin technic of sternal puncture has been modified to include iliac, spinous process and tibial marrow aspiration. 2. There has been a need for improvement and standardization of the method of handling aspirated bone marrow. 3. An improved technic of marrow aspiration is described
openaire   +2 more sources

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

THE EFFECT OF BONE MARROW ASPIRATE CONCENTRATE IN THE TREATMENT OF MANDIBULAR CYSTIC DEFECTS. A RANDOMIZED CLINICAL TRIAL [PDF]

Alexandria Dental Journal
Objective: To evaluate the effect of bone marrow aspirate concentrate in the treatment of mandibular cystic defects in comparison to the spontaneous healing using clinical and radiographic parameters.
Ahmed ElSafty, Samraa Elsheikh, Ahmed Sweedan   +2 more
doaj   +1 more source

Hyper‐Intense Tumor Peripheral Accumulation of Antibody‐Conjugated Iron Oxide Nanoparticles can Enable Breast Cancer Detection by Magnetic Particle Imaging

Advanced Science, EarlyView.
Tumor‐associated inflammation retains antibody‐targeted or non‐specific antibody conjugated nanoparticles within the tumor microenvironment. Magnetic Particle Imaging (MPI) enables non‐invasive detection and differentiation of tumors from other organs, owing to higher nanoparticle retention by inflammatory cells in the tumor periphery.
Preethi Korangath, Hayden Carlton, Theresa Wong, Sean Healy, Toby Sanders, Mason Song, Patrick W. Goodwill, Cordula Grüttner, Kathleen Gabrielson, Robert Ivkov   +9 more
wiley   +1 more source

Demonstration of early functional compromise of bone marrow derived hematopoietic progenitor cells during bovine neonatal pancytopenia through in vitro culture of bone marrow biopsies [PDF]

, 2012
Background Bovine neonatal pancytopenia (BNP) is a syndrome characterised by thrombocytopenia associated with marked bone marrow destruction in calves, widely reported since 2007 in several European countries and since 2011 in New Zealand. The disease is
Melzi Eleonora, Bell Charlotte R, Bell, Charlotte, Charlotte R Bell, Keith T Ballingall, Kim Willoughby, Scholes, Sandra F E, Dagleish, Mark P, Rocchi Mara S, Ballingall Keith T, Laming, Eleanor, Scholes Sandra FE, Laming Eleanor, Rocchi, Mara S, Maira Connelly, Melzi, Eleonora, Connelly Maira, Willoughby Kim, Ballingall, Keith T, Connelly, Maira, Dagleish Mark P, Eleanor Laming, Eleonora Melzi, Mark P Dagleish, Mara S Rocchi, Willoughby, Kim, Sandra FE Scholes   +26 more
core   +1 more source

Reversing Macrophage Immunometabolic Dysfunction in Prolonged Infections Via a Glutaminolysis‐Fueled Restoration‐Based Hierarchically Selective Therapeutic System

Advanced Science, EarlyView.
A hierarchically selective immunotherapeutic nanoplatform, mGls@HEV‐MTP, selectively restores macrophage immunocompetence through GLS1‐mediated restoration of glutaminolysis‐fueled anaplerosis. Concurrently, it renders Staphylococcus aureus (S. aureus) more readily recognizable to the metabolically reprogrammed macrophages, thereby facilitating ...
Weinan Yang, Zihao An, Honglu Cai, Congsun Li, Jiaxuan Zou, Wushi Cui, Wentao Chen, Tao Zhang, Shicheng Wang, Zizhan Su, Jian Xiao, Tao Sun, Bin Hu, Min Cheng, Zhongru Gou, Jianbin Xu, An Liu, Haobo Wu   +17 more
wiley   +1 more source

The role of bone marrow derived cells in cardiac repair [PDF]

, 2012
PhDCurrent pharmacological therapies fail to address the final end-point of cardiac ischaemia — the death and dysfunction of cardiomyocytes. Advances in stem cell biology have provided hope, for the first time, of addressing this underlying pathology.
Lovell, Matthew J.
core   +4 more sources

Phases 1–3 Clinical Trials Using Adult Stem Cells in Osteonecrosis and Nonunion Fractures

Stem Cells International, 2010
Nonunion fractures and aseptic bone necrosis are two pathological conditions having some impairment of the cellular part of the repair: a reduction of MSC and of the osteoblastic activation.
Jean-Philippe Hauzeur, Valérie Gangji
doaj   +1 more source

Multifunctional Nanovaccine‐Radiotherapy Synergy Drives Anti‐Tumor Immunity via Multi‐Cascade Cell Death for Pancreatic Cancer Therapy

Advanced Science, EarlyView.
Machine‐learning‐driven transcriptomic analysis identifies FSTL3 as a key tumor‐microenvironment regulator in desmoplastic pancreatic adenocarcinoma. A cRGD‐modified liposome co‐loading gemcitabine and siFSTL3 serves as an irradiation‐triggered in situ nanovaccine. It synergizes with radiotherapy to induce ferroptosis and immunogenic cell death through
Chengyi Huang, Yushu Han, Xiang Liu, Chuanhao Wang, Xiaofei Zhu, Di Chen, Yangyang Gong, Liang Chen, Wenjuan Chen, Zhenyuan Miao, Bufu Tang, Huojun Zhang   +11 more
wiley   +1 more source