Results 111 to 120 of about 1,067,274 (289)

Visceral leishmaniasis and haemophagocytic syndrome in an Omani child

Sultan Qaboos University Medical Journal, 2002
The paper reports the case of a previously healthy 4-year-old-girl who presented with pallor, fever and hepatosplenomegaly. Laboratory findings included pancytopenia, hypertriglyceridemia and hyperferritinemia. Initial diagnosis of kala-azar could not be
Khalfan Al Sineidi, Yasser A. Wali, Zakia Al Lamki, Anil V. Pathare   +3 more
doaj  

Intravenous Lipopolysaccharide Challenge in Healthy Participants Reveals Pharmacodynamic Markers in Blood and Bone Marrow for Early‐Phase Oncology Drug Development

Clinical Pharmacology &Therapeutics, EarlyView.
Demonstrating pharmacological effects in early‐phase oncology clinical trials remains challenging, largely due to the lack of robust pharmacodynamic markers. Lipopolysaccharide (LPS) is used as an immune challenge agent in healthy participants to study drugs for autoimmune conditions.
Igor Radanović, Ingrid Tomljanović, Wieke H. Grievink, Diana R. Pereira, Michelle Osse, Peter van Balen, Maria J. Juachon, Marieke L. de Kam, Lisa Pagan, Manon A.A. Jansen, Matthijs Moerland, Jacobus J. Bosch   +11 more
wiley   +1 more source

Pleiomorph bone marrow smear (human)

, 2007
Stain: May-Grnwald-Giemsa (MGG). Low power view of a normal bone marrow smear. The bone marrow is pleiomorph and contains all cell types such as a large reticulum cells (1) with many granules or lysosomes (phagocytosis); myeloid cells (2); and ...
Poels, Lambert G.
core  

A Robust Computational Workflow Utilizing Generalized Least Squares (GLS) and Generalized Estimating Equations (GEE‐GLM) for Longitudinal Flow Cytometry Maturation Data Analysis

Cytometry Part A, EarlyView.
ABSTRACT Routinely used statistical hypothesis tests are often inadequate for longitudinal flow cytometry data, necessitating more sophisticated modeling approaches. Analyzing dynamic biomarker expression across hematopoietic maturation presents several analytical challenges, notably nonlinearity, serial correlation between subsequent stages, and ...
Sixuan Joanna Wang, Ruben Deneer, Tom Schoenmakers, Stefan G. C. Mestrum, Yvonne M. C. Henskens, Otto Bekers, Anton H. N. Hopman, Frans C. S. Ramaekers, Mathie P. G. Leers   +8 more
wiley   +1 more source

Injectable Cell-based Tissue Engineered Bone Formulations [PDF]

, 2010
PhDCurrent golden standard therapy for bone repair and regeneration involves the use of auto grafts. Nevertheless, there are many drawbacks associated with auto grafts including donor site morbidity, requirement for an invasive surgery, post-operative
Ahmadi, Raheleh
core   +2 more sources

Automated B‐cell and plasma cell identification using unsupervised clustering by FlowSOM and an excel‐based classification model

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Manual gating for plasma cell (PC) identification in multiparametric flow cytometry (MFC) is time‐consuming and operator‐dependent, especially when PCs are scarce. Artificial intelligence approaches such as unsupervised clustering (e.g., FlowSOM) map high‐dimensional data that still require expert interpretation.
Ethan James Gantana, Ernest Musekwa, Erica‐Mari Nell, Zivanai Cuthbert Chapanduka   +3 more
wiley   +1 more source

Crista biopsies of normal, hypoplastic and malignant bone marrow (human)

, 2007
Stain: Hematoxylin and eosin. The composition of three slides shows a normal bone marrow section (A), an aplastic bone marrow (B), and a malignant lymphoma in bone marrow (C). (1) Cristae. (2) Fat tissue or fat cells.
Poels, Lambert G.
core  

Coexistence of immunophenotypically normal and aberrant mast cells in patients with clonal mast cell diseases associates with more indolent subtypes and less severe disease characteristics

Cytometry Part B: Clinical Cytometry, EarlyView.
Abstract Aberrant antigen expression on mast cells (MCs) is one of the most accurate diagnostic markers for clonal MC diseases (CMCD). Although the coexistence of normal and pathologic MCs is frequently seen, the disease characteristics associated with it have been minimally investigated.
Abdulrazzaq Alheraky, Kees Meijer, Marije Nijk, Saskia K. Klein, Hanneke N. G. Oude Elberink, Ido P. Kema, André B. Mulder   +6 more
wiley   +1 more source

Prevalence of transthyretin cardiac amyloidosis in undifferentiated heart failure with preserved ejection fraction

ESC Heart Failure, Volume 12, Issue 2, Page 1176-1182, April 2025.
Abstract Aims Transthyretin amyloid cardiomyopathy (ATTR‐CM) is an increasinglyrecognized cause of heart failure with preserved ejection fraction (HFpEF), which may be diagnosed non‐invasively using 99mTc 3,3‐diphosphono‐1,2‐propanodicarboxylic acid (DPD) scintigraphy‐based diagnostic criteria.
L. Healy, G. Giblin, A. Gray, N. Starr, L. Murphy, D. O'Sullivan, E. Kavanagh, C. Howley, C. Tracey, E. Morrin, A. McDaid, A. Clarke, J.O. O'Neill, E. Joyce, M. O'Connell, N. G. Mahon   +15 more
wiley   +1 more source

SPECTRUM OF HEMATOLOGICAL DISORDERS ON BONE MARROW ASPIRATE EXAMINATION

Gomal Journal of Medical Sciences, 2015
Background: Blood disorders are very common ranging from anemias to hematological malignancies. Bone marrow aspiration is a key investigation for hematological disorders.
Muhammad Usman Anjum, Nargis Noman, Syed Humayun Shah, Muhammad Abdul Khaliq   +3 more
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