Results 1 to 10 of about 12,192 (183)

Massive Splenomegaly: A Rare Presentation of Megaloblastic Anemia [PDF]

International Journal of Hematology-Oncology and Stem Cell Research, 2021
Megaloblastic anemia is a common disorder with various manifestations. Of the many causes, cobalamin or folate deficiency can eventuate into megaloblastic anemia.
Tahereh Gholipour, Alireza Sadeghi, Padideh Oghab, Pegah Farrokhi, Azadeh Moghaddas   +4 more
doaj   +2 more sources

Thiamine-responsive megaloblastic anemia syndrome with novel compound heterozygous SLC19A2 mutations and thrombotic events: a case report [PDF]

Journal of Medical Case Reports
Background Thiamine-responsive megaloblastic anemia syndrome represents a rare autosomal recessive condition originating from mutations in the SLC19A2 gene.
Francisco Xavier Jiménez, Carlos Rojas, Heidi A. Fernandez, Rossana Ruiz-Urbáez, Carlos Reyes-Silva, Jhonatan Guamán, Mauricio Carrión, Fernando Naranjo-Saltos   +7 more
doaj   +2 more sources

Megaloblastic anemia-related iron overload and erythroid regulators: a case report [PDF]

Journal of Medical Case Reports, 2021
Background In ineffective erythropoiesis, hepcidin synthesis is suppressed by erythroid regulators, namely erythroferrone and growth differentiation factor-15.
Nicolas Vallet, Jean-Baptiste Delaye, Martine Ropert, Amélie Foucault, Noémie Ravalet, Sophie Deriaz, Thomas Chalopin, Hélène Blasco, François Maillot, Olivier Hérault, Emmanuel Gyan   +10 more
doaj   +2 more sources

Megaloblastic Anemia in Bardet-Biedl Syndrome: A Rare Case Report [PDF]

Clinical Medicine Insights: Case Reports, 2023
Background: Bardet-Biedl syndrome (BBS) also known as Laurence-Moon-Bardet-Biedl syndrome one of the rarely reported genetic disorder characterized by an intellectual disability, limb, kidney abnormalities, obesity, and Rod-cone dystrophy.
Subtain Hassan, Qaisar Ali Khan, Priyadharshini Saravanan, Sumaira Iram, Samia Rohail, Naod F Belay, Muhammad Afzal, Faiza Amatul Hadi, Harshawardhan Pande   +8 more
doaj   +2 more sources

Severe megaloblastic anemia in a patient with advanced lung adenocarcinoma during treatment with erlotinib: a case report and literature review [PDF]

BMC Pulmonary Medicine
Background Erlotinib is a first-generation, tyrosine kinase inhibitor of the epidermal growth factor receptor (EGFR-TKI) used for the treatment patients with NSCLC.
Xin Yan, Jingxian Kong, Jiacheng Wang, Caixia Wang, Hongchang Shen   +4 more
doaj   +2 more sources

Pulmonary embolism and megaloblastic anemia: is there a link? A case report an literature review [PDF]

Radiology Case Reports, 2018
Many factors have been associated with venous thromboembolism. Among them, vitamin B12 deficiency can produce elevated homocysteine levels, which is a risk factor for venous embolism, since the latter interferes with the activation of Va coagulation ...
Grecia Iveth Raymundo-Martínez, MD, Rodrigo Gopar-Nieto, MD, Gonzalo Carazo-Vargas, MD, Diego Araiza-Garaygordobil, MD, Sergio Raul Scuri, MD, Laura Leticia Rodríguez-Chavez, MD, Nilda Espinola-Zavaleta, MD, PhD   +6 more
doaj   +2 more sources

Role of LDH levels in differentiating anemias

Asian Journal of Medical Sciences, 2021
Background: There is a need to differentiate megaloblastic anemia from mixed deficiency anemia as both require different management protocols. With the acquisition of more information about them, tests such as serum vitamin estimation and Schilling test,
Noorin Zaidi , Rasha Zia Usmani , Kshama Tiwari , Sumaiya Irfan , Syed Riaz Mehdi   +4 more
doaj   +1 more source

MEGALOBLASTIC ANEMIA IN CHILDREN: CASE SERIES FROM A SINGLE INSTITUTION AND LITERATURE REVIEW [PDF]

Romanian Journal of Pediatrics, 2018
Folic acid and cobalamin are B-group vitamins that play an essential role in many cellular processes. Deficiency in one or both of these vitamins causes megaloblastic anemia, a very rare anemia in children, which is characterized by the presence of ...
Andreea Oltean, Mihaela Ioana Chincesan, Maria Despina Baghiu, Eniko Molnar, Cristina Oana Marginean   +4 more
doaj   +1 more source

Megaloblastic anemia associated with small bowel resection in an adult patient

Nigerian Journal of Medicine, 2021
Megaloblastic anemia is characterized by macro-ovalocytosis, cytopenias, and nucleocytoplasmic maturation asynchrony of marrow erythroblast. The development of megaloblastic anemia is usually insidious in onset, and symptoms are present only in severely ...
Ajayi Adeleke Ibijola, Abiodun Idowu Okunlola   +1 more
doaj   +1 more source

A novel PCFT gene mutation (p.Cys66LeufsX99) causing hereditary folate malabsorption [PDF]

, 2009
Hereditary folate malabsorption (HFM) is a rare autosomal recessive disorder which is characterized by impaired intestinal folate malabsorption and impaired folate transport into the central nervous system.
Cole, Trevor, Kurian, Manju A., Maher, Eamonn R., Meyer, Esther, Pasha, Shanaz, Trembath, Richard C.   +5 more
core   +2 more sources