Results 1 to 10 of about 179,354 (297)

Evaluation of an association of the rs1801133 MTHFR gene polymorphism with folic acid deficiency in obese patients

Alʹmanah Kliničeskoj Mediciny, 2018
Background: The use of molecular genetic technologies has made it possible to show that the genetic factor plays a significant role in the development of obesity.
A. V. Pogozheva, E. Yu. Sorokina, T. V. Aristarkhova   +2 more
doaj   +1 more source

An Opinion on the Supplementation of Folic Acid 1 mg + Iron (Ferrous Sulfate) 90 mg in the Prevention and Treatment of Anemia

BioChem
Introduction: Anemia, characterized by a reduction in hemoglobin concentration, is a widespread health concern globally, impacting individuals across various demographics.
João Gomes, Joana Brandão Silva, César Vinícius José, Hugo Ribeiro   +3 more
doaj   +1 more source

Folate deficiency in patients with classical galactosemia: A novel finding that needs to be considered for dietary treatments

The Turkish Journal of Pediatrics, 2018
The objectives of the study were to assess folate deficiency in patients with classic galactosemia, and to determine whether folic acid supplementation has an effect on galactose-1-phosphate uridyltransferase enzyme activity.
Muhittin Çelik, Nezir Özgün, Osman Akdeniz, Mücahit Fidan, Heybet Tüzün, Mehmet Şah İpek, Merve Emecan, Fatma Tuba Eminoğlu   +7 more
doaj   +1 more source

Prevalence of iron and folic acid deficiency, the effectiveness of correction in women of early reproductive age: a prospective cohort study

Акушерство, гинекология и репродукция
Introduction. Iron deficiency conditions and folate insufficiency are highly prevalent among women of reproductive age in the Russian Federation and may adversely affect menstrual and reproductive function.
K. N. Mingareeva, A. G. Yaschuk, F. F. Tashbulatova   +2 more
doaj   +1 more source

High frequencies of vitamin B12 and folic acid deficiencies and gastric parietal cell antibody positivity in oral submucous fibrosis patients

Journal of the Formosan Medical Association, 2015
Oral submucous fibrosis (OSF) is a chronic progressive scaring oral disease associated with areca quid chewing. This study evaluated whether OSF patients had anemia, hematinic deficiencies, and serum gastric parietal cell antibody (GPCA) positivity ...
Yi-Ping Wang, Yang-Che Wu, Shih-Jung Cheng, Hsin-Ming Chen, Andy Sun, Julia Yu-Fong Chang   +5 more
doaj   +1 more source

Role of folic acid in regulating gut microbiota and short-chain fatty acids based on an in vitro fermentation model

Applied Microbiology and Biotechnology
Folic acid deficiency is common worldwide and is linked to an imbalance in gut microbiota. However, based on model animals used to study the utilization of folic acid by gut microbes, there are challenges of reproducibility and individual differences. In
Xiaogu Zheng, Chenlan Xia, Manman Liu, Hong Wu, Jiaqian Yan, Zihao Zhang, Yingjie Huang, Qing Gu, Ping Li   +8 more
semanticscholar   +1 more source

Association of Folic Acid Deficiency with Ischemic Heart Disease

Journal of Rawalpindi Medical College, 2018
Background: To assess the association between folic acid deficiency and ischemic heart disease Methods: In this observational study patients of 25-65 years of age with newly diagnosed ischemic heart disease were included.
Mubashar Yameen, Muhammad Maqsood, Maimona Saleh, Imtiaz Ahmed Shakir, Atifa Shuaib   +4 more
doaj  

High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice

American Journal of Clinical Nutrition, 2015
Background: Increased consumption of folic acid is prevalent, leading to concerns about negative consequences. The effects of folic acid on the liver, the primary organ for folate metabolism, are largely unknown.
Karen E. Christensen, Leonie G. Mikael, K. Leung, N. Lévesque, Liyuan Deng, Qing Wu, O. Malysheva, A. Best, M. Caudill, N. Greene, R. Rozen   +10 more
semanticscholar   +1 more source

Adherence to iron-folic acid supplementation among pregnant women in Ethiopia: a systematic review and meta-analysis

BMC Pregnancy and Childbirth, 2020
Background Despite the supplementation of iron-folic acid is the recommended strategy during the antenatal period; iron deficiency anemia is the commonest hematologic complication during pregnancy.
Fikadu Waltengus Sendeku, G. Azeze, Selamawit Lake Fenta   +2 more
semanticscholar   +1 more source

Folate dietary insufficiency and folic acid supplementation similarly impair metabolism and compromise hematopoiesis

Haematologica, 2017
While dietary folate deficiency is associated with increased risk for birth defects and other diseases, evidence suggests that supplementation with folic acid can contribute to predisposition to some diseases, including immune dysfunction and cancer ...
Curtis J. Henry, Travis Nemkov, Matias Casás-Selves, Ganna Bilousova, Vadym Zaberezhnyy, Kelly C. Higa, Natalie J. Serkova, Kirk C. Hansen, Angelo D’Alessandro, James DeGregori   +9 more
doaj   +1 more source