Results 31 to 40 of about 179,354 (297)

Maternal folic acid deficiency stimulates neural cell apoptosis via miR‐34a associated with Bcl‐2 in the rat foetal brain

open access: yesInternational Journal of Developmental Neuroscience, 2018
Embryonic development is a critical period wherein brain neurons are generated and organized. Maternal dietary folate, a cofactor in one‐carbon metabolism, modulates neurogenesis and apoptosis in foetal brain neurons.
Wen Li   +5 more
semanticscholar   +1 more source

Women Taking a Folic Acid Supplement in Countries with Mandatory Food Fortification Programs May Be Exceeding the Upper Tolerable Limit of Folic Acid: A Systematic Review

open access: yesNutrients, 2022
Background: In preconception and pregnancy, women are encouraged to take folic acid-based supplements over and above food intake. The upper tolerable limit of folic acid is 1000 mcg per day; however, this level was determined to avoid masking a vitamin ...
Carolyn Ledowsky   +3 more
semanticscholar   +1 more source

The Concept of Folic Acid in Health and Disease

open access: yesMolecules, 2021
Folates have a pterine core structure and high metabolic activity due to their ability to accept electrons and react with O-, S-, N-, C-bounds.
Yulia Shulpekova   +9 more
semanticscholar   +1 more source

Assessment of folic acid and DNA damage in cleft lip and cleft palate

open access: yesClinics and Practice, 2014
Studies have identified the risk factors like folic acid deficiency during gestational period, family history for orofacial clefts, drugs like antiepileptic, vitamin A.
Sivakumar Brooklyin   +4 more
doaj   +1 more source

Vitamin B12 status and folic acid/vitamin B12 related to the risk of gestational diabetes mellitus in pregnancy: a systematic review and meta-analysis of observational studies

open access: yesBMC Pregnancy and Childbirth, 2022
Background This review was conducted to investigate the association between serum vitamin B12 levels as well as folic acid/vitamin B12 during pregnancy and the risk of gestational diabetes mellitus (GDM).
Jin He, Dongmei Jiang, X. Cui, C. Ji
semanticscholar   +1 more source

Prevalence of low folate deficiency after wheat flour supplementation – should we still measure serum folate?

open access: yesHematology, Transfusion and Cell Therapy, 2018
Objectives: To determine the frequency of folic acid deficiency in consecutive serum folate determinations and to determine whether there was a significant decrease in serum folate deficiency after folate was added to wheat flour.
Alejandro Godoy, Aldo Hugo Tabares
doaj   +1 more source

Lack of historical evidence to support folic acid exacerbation of the neuropathy caused by vitamin B12 deficiency

open access: yesAmerican Journal of Clinical Nutrition, 2019
In 1998 a Tolerable Upper Intake Level (UL) for folic acid was established based on case reports from the 1940s suggesting that high-dosage folic acid intake, used to treat patients with pernicious anemia, had the potential to precipitate or speed-up the
R. Berry
semanticscholar   +1 more source

Does Folic Acid Protect Patients with Inflammatory Bowel Disease from Complications?

open access: yesNutrients, 2021
Folic acid, referred to as vitamin B9, is a water-soluble substance, which participates in the synthesis of nucleic acids, amino acids, and proteins. Similarly to B12 and B6, vitamin B9 is involved in the metabolism of homocysteine, which is associated ...
A. Ratajczak   +5 more
semanticscholar   +1 more source

Epidemiology and (Patho)Physiology of Folic Acid Supplement Use in Obese Women before and during Pregnancy

open access: yesNutrients, 2021
Preconception folic acid supplement use is a well-known method of primary prevention of neural tube defects (NTDs). Obese women are at a higher risk for having a child with a NTD.
M. van der Windt   +5 more
semanticscholar   +1 more source

Rapid Assessment for Coexistence of Vitamin B12 and Iron Deficiency Anemia among Adolescent Males and Females in Northern Himalayan State of India

open access: yesAnemia, 2013
Coexistence of folic acid and vitamin B12 deficiency has been observed among adolescents with iron deficiency anemia, but limited evidence is available from India.
Ashok Bhardwaj   +5 more
doaj   +1 more source

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