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Folic Acid Deficiency [PDF]

Postgraduate Medical Journal, 1961
MACROCYTIC anamia, associated with a megaloblastic erythropoiesis, glossitis, weight loss, diarrhcra, and an absence of neurological symptoms or signs and of evidence of deficiency of vitamin B12 are usually accepted as the features of deficiency of folic acid or related pteroylglutamate compounds.
E V, COX, M J, MEYNELL, W T, COOKE
openaire   +3 more sources

Epigenetic regulation mechanism of folic acid deficiency inhibiting Brachyury expression and its effect on differentiation of embryoid bodies

陆军军医大学学报, 2022
Objective To investigate the epigenetic regulation mechanism of folic acid deficiency in inhibition of the expression of Brachyury, a key developmental gene, and its effect on the differentiation of embryoid bodies (EBs). Methods Firstly, the cell model
CHANG Shaoyan, GUO Jiuye, CHEN Yan
doaj   +1 more source

STAT6 Deficiency Attenuates Myeloid Fibroblast Activation and Macrophage Polarization in Experimental Folic Acid Nephropathy

Cells, 2021
Renal fibrosis is a pathologic feature of chronic kidney disease, which can lead to end-stage kidney disease. Myeloid fibroblasts play a central role in the pathogenesis of renal fibrosis.
B. Jiao, Changlong An, Hao Du, Melanie Tran, Penghua Wang, Dong Zhou, Yanlin Wang   +6 more
semanticscholar   +1 more source

Varied Clinico-haematological Presentation of Patients of Megaloblastic Anaemia with Deficiency of Vitamin B12 and Folic Acid in a Tertiary Care Center of Northern India [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Megaloblastic anaemia is caused by vitamin B12 and/or folic acid deficiency. Clinically megaloblastic anaemia may present as a continuum of asymptomatic metabolic abnormalities ranging to life-threatening clinical syndrome.
Amreen Brown, Nishi Tandon, Syed Riaz Mehdi, Zeba Siddiqui   +3 more
doaj   +1 more source

Neural network analysis of the correlation between malnutrition-induced stomatitis and vitamin B12 and folic acid

口腔疾病防治, 2022
Objective A model was built by neural network analysis to study the relationship between different degrees of vitamin B12 and folic acid deficiency and malnutrition-induced stomatitis.
LI Ruowei, LIU Ke, ZHANG Miaomiao, XIE Ruiqi, DUAN Ning, WANG Wenmei, WANG Xiang   +6 more
doaj   +1 more source

Knowledge on anaemia and benefit of iron–folic acid supplementation among pregnant mothers attending antenatal care in Woldia town, Northeastern Ethiopia: a facility-based cross-sectional study

Journal of Health, Population and Nutrition, 2022
Background Anaemia in pregnancy is the leading cause of maternal morbidity and mortality and poor birth outcomes in low- and middle-income countries.
Asmamaw Demis Bizuneh, Getnet Gedefaw Azeze   +1 more
doaj   +1 more source

Folic Acid, Folinic Acid, 5 Methyl TetraHydroFolate Supplementation for Mutations That Affect Epigenesis through the Folate and One-Carbon Cycles

Biomolecules, 2022
Methylation is an essential biochemical mechanism that is central to the transmission of life, and crucially responsible for regulating gametogenesis and continued embryo development.
Y. Menezo, K. Elder, A. Clément, P. Clément   +3 more
semanticscholar   +1 more source

Folic acid - importance for human health and its role in COVID-19 therapy

Roczniki Panstwowego Zakladu Higieny, 2023
Folic acid (folacin, B9) is a vitamin that performs many very important functions in the human body, and its inadequate level - deficiency as well as excess, may contribute to an increased risk of developing many disease processes.
Katarzyna Kurowska, Milena Kobylińska, Katarzyna Antosik   +2 more
doaj   +1 more source

Folic acid ameliorates alcohol-induced liver injury via gut–liver axis homeostasis

Frontiers in Nutrition, 2022
The gut–liver axis (GLA) plays an important role in the development of alcohol-induced liver injury. Alcohol consumption is typically associated with folic acid deficiency. However, no clear evidence has confirmed the effect of folic acid supplementation
Huaqi Zhang, Yuwei Zuo, Huichao Zhao, H Zhao, Yutong Wang, Xinyu Zhang, Jiacheng Zhang, Peng Wang, Lirui Sun, Huizhen Zhang, Huichang Liang   +10 more
semanticscholar   +1 more source

Oral Manifestations of Nutritional Deficiencies: Single Centre Analysis

Acta Medica, 2020
Introduction: Oral manifestations of deficiency of iron, vitamin B12 and folic acid are thought to be common. Prevalence of these deficiencies among patients with compatible symptoms is not well known.
Vladimíra Radochová, Radovan Slezák, Jakub Radocha   +2 more
doaj   +1 more source