Results 141 to 150 of about 1,067,274 (289)

KAT8‐Low Osteosarcoma Suppresses Cisplatin Sensitivity via H4K16ac‐Mediated Cell Apoptosis

Med Research, EarlyView.
The scientific significance of this study is highlighted below: (1) Data mining and clinical discovery: These findings establish a direct clinical link between the KAT8–H4K16ac axis and chemotherapy response in osteosarcoma. (2) Multi‐omics and machine‐learning integration: We integrated proteomics and CUT&Tag multi‐omics to elucidate how chromatin ...
Zhenqun Zhao, Guohui Yu, Shikui Wu, Zhiyang Zhang, Keke Wang, Yingxin Xiong, Chao Sun, Haobo Cui, Yuxing Wang, Ziheng Wang, Huiru Zhang, Huiqin Xue, Shibing Guo   +12 more
wiley   +1 more source

CORR Insights®: Is Bone Marrow Aspiration and Biopsy of Clinical Importance in the Initial Staging of Extraskeletal Ewing Sarcoma? [PDF]

Clin Orthop Relat Res, 2023
Papagelopoulos PJ.
europepmc   +1 more source

Protein and gene expression analyses in bone marrow stem cells mediated restoration of myocardium after ischemic insult [PDF]

, 2010
PhDMyocardial Infarction (MI) is caused by occlusion of the coronary artery following atheromatous plaque rupture, the subsequent ischemia in the myocardium leads to myocyte necrosis unless treated quickly. Bone marrow derived stem cell treatment is a
Lee, Kate L
core  

Senotherapeutics for Knee Osteoarthritis

Medicinal Research Reviews, EarlyView.
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman, Girish Pattappa, Patrick Pann, Stephan Reppenhagen, Maximilian Rudert, Peter Angele, Denitsa Docheva   +6 more
wiley   +1 more source

Bone Marrow Aspirate [PDF]

, 2020
openaire   +1 more source

From Past Achievements to Future Hotspots: Bibliometric View of Influential Studies on Microfracture Research

Medicine Advances, EarlyView.
This study utilized bibliometrics to summarize research activity and global collaboration in impactful microfracture literature. The United States is the leading contributor to microfracture research, accounting for 34% of the top 100 cited publications, followed by Germany (10%) and Italy (9%).
Boshen Shu
wiley   +1 more source

Polycythemia in bone marrow smear (human)

, 2007
Stain: Hematoxylin and eosin. Low power view. Polycythemic phase. Hypercellular marrow as a result of excessive proliferation of erythroid cells (numerous dark nuclei) and of the megakaryocytic lineage (tendency to cluster). (1) fat cells in bone marrow.
Poels, Lambert G.
core  

Bone marrow aspiration and biopsy

, 1991
Bone marrow aspiration and biopsy have a central place in the diagnosis of haematological disorders. Marrow procedures have a reputation for being unpleasant and painful but when performed carefully, with appropriate use of local anaesthetic and ...
Smith, A G, Williamson, P J
core   +1 more source

Semi‐mechanistic population PK/PD model to aid clinical understanding of myelodysplastic syndromes following treatment with Venetoclax and Azacitidine

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 448-459, March 2025.
Abstract Myelodysplastic syndromes (MDS) represent a group of bone marrow disorders involving cytopenias, hypercellular bone marrow, and dysplastic hematopoietic progenitors. MDS remains a challenge to treat due to the complex interplay between disease‐induced and treatment‐related cytopenias.
Neha Thakre, Corinna Maier, Jiuhong Zha, Benjamin Engelhardt, Johannes E. Wolff, Sven Mensing   +5 more
wiley   +1 more source

Reorientation technique has benefits in bone marrow aspiration of stem cells. [PDF]

Sci Rep, 2022
Pabinger C, Dammerer D, Lothaller H, Kobinia GS.   +3 more
europepmc   +1 more source