Advanced Functional Materials, EarlyView.A bimetallic Mn–Ca nanoreactor (MCC) is developed as a non‐nucleotide STING nanoagonist for cancer metalloimmunotherapy. MCC induces Ca2+ overload and hydroxyl radical generation, resulting in mitochondrial damage and mtDNA release. The released mtDNA cooperates with Mn2+ to robustly activate cGAS–STING signaling.
Xin Wang Mo +7 more
wiley +1 more source
Radiation Induces Apoptosis and Osteogenic Impairment through miR-22-Mediated Intracellular Oxidative Stress in Bone Marrow Mesenchymal Stem Cells [PDF]
, 2018 Zhonglong Liu +5 more
openalex +1 more source
Myeloblasts Under 20 Percent of Bone Marrow Nucleated Cells [PDF]
, 2020 National Cancer Institute
openalex +1 more source
Synthetic Nanobiology Actuated Lipometabolic Cell Factory for Autologous Tumor Immunotherapy
Advanced Functional Materials, EarlyView.FA plays a crucial role in the interaction between tumor cells and the tumor microenvironment, especially for the immune response. A biocatalytic immunoenhancement strategy is developed to boost antitumor immunity by FA metabolic orientation to ceramide. Through the design of this delicate catalytic immunoenhancement strategy, the synthetic nanobiology
Shoujie Zhao +8 more
wiley +1 more source
Neuroamines — regulators of local processes at bone marrow autotransplantation [PDF]
Саратовский научно-медицинский журнал, 2015 Purpose: to determine the content of neuroamines (histamine, serotonin, catecholamines) in bioamine structures of bone marrow after autotransplantation. Material and methods.
Vorobyova O.V.
doaj
Split chimerism between nucleated and red blood cells after bone marrow transplantation for haemoglobinopathies [PDF]
, 2011 Marco Andreani +3 more
openalex +1 more source
Cold Quad‐Modal Nanocomplex for Precise and Quantitative In Vivo Stem Cell Tracking
Advanced Functional Materials, EarlyView.Multimodal albumin–bismuth sulfide–superparamagnetic iron oxide (ABS) nanocomplexes are developed for stem cell tracking across four different imaging modalities: MRI, MPI, MSOT, and CT. Combining its flexibility with high sensitivity, this quad‐modal imaging agent enables a robust quantification of ABS‐labeled stem cells in vivo.
Ali Shakeri‐Zadeh +4 more
wiley +1 more source
Experiment K-6-23. Effect of spaceflight on levels and function of immune cells [PDF]
Two different immunology experiments were performed on samples received from rats flown on Cosmos 1887. In the first experiment, rat bone marrow cells were examined in Moscow for their response to colony stimulating factor-M.
Berry, W. +7 more
core +1 more source
Cell Surface Thiol Engineering Mechanoregulates Myogenic Differentiation via the FAK–PI3K–AKT Axis
Advanced Healthcare Materials, EarlyView.Schematic diagram illustrating how cell surface modification of skeletal muscle progenitor cells through TCEP treatment reveals enhanced cell adhesion, intracellular tension, and myogenesis at 19.66 kPa stiffness, leading to optimal cell fusion. In contrast, no significant changes are observed in the softer (10.61 kPa) or stiffer (49.4 kPa) matrices ...
Juyeon Kim +10 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Early bone regeneration is challenged by poor osteogenic microenvironments. We developed a novel guided bone regeneration (GBR) membrane: a plasma‐treated polycaprolactone (PT‐PCL) electrospun nanofiber functionalized with ultrasound sequentially extruded stromal vascular fraction chimeric vesicles (USE‐SCNVs). USE‐SCNVs require less equipment, enhance
Yufan Zhang +13 more
wiley +1 more source