Results 81 to 90 of about 1,176,323 (360)

Exploring the role of cyclin D1 in the pathogenesis of multiple myeloma beyond cell cycle regulation

open access: yesMolecular Oncology, EarlyView.
Cyclin D1 overexpression altered the cell adhesion pathway, while cyclin D2 upregulation had less impact on pathway enrichment analysis. Multiple myeloma (MM) patients with cyclin D1 overexpression showed reduced CD56 expression and increased circulating tumor cells (CTC) levels, suggesting that cyclin D1 may contribute to MM cell dissemination ...
Ignacio J. Cardona‐Benavides   +13 more
wiley   +1 more source

MOBILIZATION OF STEM CELLS AFTER LIVER TRANSPLANTATION AND RESECTION

open access: yesВестник трансплантологии и искусственных органов, 2010
The review article analyses the published literature for mobilization of CD34/CD45 positive bone marrow cells into peripheral blood after liver injury.
R. M. Kurabekova   +2 more
doaj   +1 more source

Intracoronary bone marrow-derived progenitor cells in acute myocardial infarction.

open access: yesNew England Journal of Medicine, 2006
BACKGROUND Pilot trials suggest that the intracoronary administration of autologous progenitor cells may improve left ventricular function after acute myocardial infarction.
V. Schächinger   +14 more
semanticscholar   +1 more source

The critical role of DNA damage‐inducible transcript 4 (DDIT4) in stemness character of leukemia cells and leukemia initiation

open access: yesMolecular Oncology, EarlyView.
Stemness properties, including quiescence, self‐renewal, and chemoresistance, are closely associated with leukemia relapse. Here, we demonstrate that DNA damage‐inducible transcript 4 (DDIT4) is induced in the hypoxic bone marrow niche and is essential for maintaining the stemness of AML1‐ETO9a leukemia cells.
Yishuang Li   +12 more
wiley   +1 more source

Combined single-cell and spatial transcriptomics reveals the molecular, cellular and spatial bone marrow niche organization

open access: yesNature Cell Biology, 2019
The bone marrow constitutes the primary site for life-long blood production and skeletal regeneration. However, its cellular and spatial organization remains controversial.
Chiara Baccin   +9 more
semanticscholar   +1 more source

Microglia limit brain tumor development by restricting tumor cell proliferation and inducing T‐cell immunity

open access: yesMolecular Oncology, EarlyView.
Microglia (BV2) and IL‐4‐treated BMDMs promote astrocytoma clustering and inhibit tumor growth, not shown in other macrophage cells. In vivo, microglial co‐implantation enhances CD8+ T cell infiltration, elevates Granzyme B, lowers circulating MDSCs, and extends survival only in immune‐competent mice, but not in immune‐deficient mice.
Tzu‐Chieh Sun   +5 more
wiley   +1 more source

Absorption Microspectroscopy of Bone Marrow Cells [PDF]

open access: yesBlood, 1955
Abstract Using a microspectrographic technic, reflecting optics and narrow bands of the continuum (5500, 4150 and 2650 Å), the author has obtained pictures of human and rat bone marrow cells in unfixed dry smears as well as in suspensions in vivo; erythroblasts showed different absorption patterns.
openaire   +3 more sources

DNA Barcoding Reveals Habitual Clonal Dominance of Myeloma Plasma Cells in the Bone Marrow Microenvironment

open access: yesNeoplasia: An International Journal for Oncology Research, 2017
Multiple myeloma (MM) is a hematological malignancy resulting from the uncontrolled proliferation of antibody-producing plasma cells in the bone marrow. At diagnosis, independent plasma cell tumors are found throughout the skeleton.
Duncan R. Hewett   +7 more
doaj   +1 more source

Biocompatibility of bone marrow mesenchymal cells on polyetheretherketone and titanium surfaces in vitro

open access: yes口腔疾病防治, 2020
Objective To compare the in vitro biocompatibility of bone marrow mesenchymal cells on polyetheretherketone (PEEK) and titanium (Ti) surfaces. Methods PEEK and Ti foils with thicknesses of 1 mm and diameters of 10 mm were prepared.
LIAN Keqian   +4 more
doaj   +1 more source

Possible role of human ribonuclease dicer in the regulation of R loops

open access: yesFEBS Open Bio, EarlyView.
R loops play an important role in regulating key cellular processes such as replication, transcription, centromere stabilization, or control of telomere length. However, the unscheduled accumulation of R loops can cause many diseases, including cancer, and neurodegenerative or inflammatory disorders. Interestingly, accumulating data indicate a possible
Klaudia Wojcik   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy