Results 1 to 10 of about 347,953 (267)

Hemostatic and thrombotic parameters in acure leukemia- A comparison of pre and post remission induction phase

open access: yesLiaquat Medical Research Journal, 2022
This study was aimed to compare hemostatic, fibrinolytic and thrombotic parameters in pre and post induction chemotherapy in acute myeloid leukemia (AML) and acute lymphoid leukemia (ALL).
Tehmina Nafees Sonia Khan   +5 more
doaj   +1 more source

Sequencing of SARS-CoV-2 in local transmission cases through Oxford Nanopore MinION platform from Karachi Pakistan

open access: yesJournal of Infection in Developing Countries, 2021
Introduction: The first case of severe acute respiratory syndrome 2 (SARS-CoV-2) was imported to Pakistan in February 2020, since then 8,260 deaths have been witnessed.
Samina Naz Mukry   +6 more
doaj   +1 more source

A distinct molecular mutational profile and its clinical impact in essential thrombocythemia and primary myelofibrosis patients

open access: yesBMC Cancer, 2020
Background Classical MPNs including ET and PMF have a chronic course and potential for leukaemic transformation. Timely diagnosis is obligatory to ensure appropriate management and positive outcomes.
Uzma Zaidi   +9 more
doaj   +1 more source

Environmental and occupational determinants of myelodysplastic syndrome: A case–control study from Pakistan

open access: yesCancer Reports, 2022
Background Myelodysplastic syndromes (MDS) are heterogeneous group of haematopoietic stem cell disorders and have variable reduction in the production of red cells, platelets and mature granulocytes.
Nida Anwar   +5 more
doaj   +1 more source

Usefulness of convalescent plasma transfusion for the treatment of severely ill COVID-19 patients in Pakistan

open access: yesBMC Infectious Diseases, 2021
Background Convalescent plasma(CP) was utilized as potential therapy during COVID-19 pandemic in Pakistan. The study aimed at appraisal of CP transfusion safety and usefulness in COVID pneumonia.
Tehmina Nafees Sonia Khan   +15 more
doaj   +1 more source

Influence of cytochrome P450 and glutathione S transferase polymorphisms on response to nilotinib therapy among chronic myeloidleukemia patients from Pakistan

open access: yesBMC Cancer, 2022
Background Cytochrome P450 (CYP) and glutathione S transferases (GSTs) are important biotransforming enzymes responsible for detoxification of anticancer drugs and carcinogens.
Samina Naz Mukry   +3 more
doaj   +1 more source

Clinical Relevance of Extended Platelet Indices in the Diagnosis of Immune Thrombocytopenia

open access: yesActa Clinica Croatica, 2021
Immune thrombocytopenia (ITP) is an autoimmune disorder. Besides platelet count, immature platelet fraction (IPF) can be used as a tool to predict megakaryocytic activity in ITP patients.
Aisha Arshad   +2 more
doaj   +1 more source

Successful management of colistin- and carbapenem-resistant -associated ecthyma gangrenosum in acute myeloid leukemia: A rare complication

open access: yesSAGE Open Medical Case Reports, 2022
Pseudomonal ecthyma gangrenosum is a well-known condition in immunosuppressed patients. However, ecthyma gangrenosum associated with Klebsiella pneumoniae is a rare entity that requires early recognition and optimal antibiotic and surgical management. We
Aisha Jamal   +4 more
doaj   +1 more source

Effect of hydroxyurea on quality of life with a moderating role of healthcare professionals’ performance: A view from the beta-thalassemia patients.

open access: yesInternational Journal of Endorsing Health Science Research, 2022
Background: Transfusion-dependent (TDT) β –Thalassemia patients have lower HRQoL than healthy individuals. The impact of Hydroxyurea is always measured with the clinical investigations in terms of laboratory diagnosis.
Affaf Sheikh   +4 more
doaj   +3 more sources

Case Report: Invasive Fungal Infection and Daratumumab: A Case Series and Review of Literature

open access: yesFrontiers in Oncology, 2022
Life expectancy of multiple myeloma (MM) patients has improved in last years due to the advent of anti-CD38 monoclonal antibodies in combination with immunomodulators and proteasome inhibitors.
Francesca Farina   +16 more
doaj   +1 more source

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