Results 21 to 30 of about 548,525 (315)

Bone marrow transplantation for autoimmune diseases

Current Opinion in Oncology, 1999
Autoimmune diseases afflict approximately 2% of the US population and span virtually every medical specialty. Most patients with autoimmune diseases have a normal life expectancy and are managed conservatively; however, a subset of patients have a progressive disease course associated with significant morbidity and mortality.
R A, Brodsky, B D, Smith
openaire   +5 more sources

Bone Marrow–on–a–Chip Replicates Hematopoietic Niche Physiology in Vitro [PDF]

, 2014
Current in vitro hematopoiesis models fail to demonstrate the cellular diversity and complex functions of living bone marrow; hence, most translational studies relevant to the hematologic system are conducted in live animals.
Collins, James J., Ingber, Donald Elliot, Mammoto, Akiko, Mammoto, Tadanori, Spina, Catherine, Tat, Tracy, Torisawa, Yu-suke, Weaver, James C.   +7 more
core   +1 more source

The unbearable lightness of bone marrow homeostasis [PDF]

, 2015
The anatomical and functional dimensions of bone marrow topography have been at the forefront of modern bone and immunological research for many years and remain a source of complexity and perplexity due to the multitude of microhabitats within this ...
AGAS, DIMITRIOS, Douni E., MARCHETTI, Luigi, SABBIETI, Maria Giovanna   +3 more
core   +1 more source

Genomic profile of a patient with triple negative essential thrombocythemia, unresponsive to therapy: A case report and literature review

Journal of Advanced Research, 2017
Clonal analysis of patients with triple negative myeloproliferative neoplasm (MPN) has provided evidence of additional aberrations, including epigenetic alterations.
Uzma Zaidi, Saba Shahid, Naveen Fatima, Shariq Ahmed, Gul Sufaida, Muhammad Nadeem, Tahir Shamsi   +6 more
doaj   +1 more source

Quality of Life and psychopathology in adults who underwent Hematopoietic Stem Cell Transplantation (HSCT) in childhood: a qualitative and quantitative analysis. [PDF]

, 2017
Background: Patients who undergo pediatric Hematopoietic Stem Cell Transplantation (HSCT) may experience long-term psychological sequelae and poor Quality of Life (QoL) in adulthood. This study aimed to investigate subjective illness experience, QoL, and
Basso, G., Boscolo, Valentina, Calore, E., Cattelan, C., Di Florio, N., Mainardi, C., Marzollo, A., Messina, C., Pillon, M., Porreca, A., Sinatora, F., Traverso, A., Tremolada, M., Zanato, S.   +13 more
core   +2 more sources

Correction to: Identification of novel mutations in congenital afibrinogenemia patients and molecular modeling of missense mutations in Pakistani population

Thrombosis Journal, 2019
Following the publication of this article [1], the authors noted the following typographical errors.
Arshi Naz, Arijit Biswas, Tehmina Nafees Khan, Anne Goodeve, Nisar Ahmed, Nazish Saqlain, Shariq Ahmed, Ikram Din Ujjan, Tahir S. Shamsi, Johannes Oldenburg   +9 more
doaj   +1 more source

COVID-19 and humoral immune response in convalescent plasma donors in Pakistani cohort.

Liaquat Medical Research Journal, 2022
Current COVID-19 pandemic has affected the entire globe. While there was no vaccine neither any specific treatment, investigational use of convalescent plasma has been explored in clinical trials.
Jawad Hassan, Shahtaj Masood, Naveena Fatima, Tehmina Khan, Javed Akram, Faridoon Ahmad, Lubna Meraj, Ayesha Mahesar, Zaratul Ain Malik, Nadeem samad Sheikh, Irfan Ghafoor baig, Mohammad Adil, Muhammad Asif, Sidra Maqsood, Mahjabeen Imam, Durenaz Jamal, Dilnasheen Safdar, Tahir Shamsi   +17 more
doaj   +1 more source

Texture analysis of vertebral bone marrow using chemical shift encoding–based water-fat MRI:a feasibility study [PDF]

, 2019
Summary This feasibility study investigated the spatial heterogeneity of the lumbar vertebral bone marrow using chemical shift encoding–based water-fat MRI. Acquired texture features like contrast and dissimilarity allowed for differentiation of pre- and
Baum, T., Burian, E., Dieckmeyer, M., Diefenbach, M.N., Hedderich, D.M., Karampinos, D.C., Kirschke, J.S., Mookiah, M.R.K., Rohrmeier, A., Rummeny, E.J., Ruschke, S., Subburaj, K., Zimmer, C.   +12 more
core   +2 more sources

RAGs and Regulation of Autoantibodies [PDF]

, 2004
Autoreactive antibodies are etiologic agents in a number of autoimmune diseases. Like all other antibodies these antibodies are produced in developing B cells by V(D)J recombination in the bone marrow.
Casellas, Rafael, Jankovic, Mila, Nussenzweig, Michel C., Wardemann, ­Hedda, Yannoutsos, Nikos   +4 more
core   +1 more source

A Novel Nonsense Mutation in FERMT3 Causes LAD-III in a Pakistani Family

Frontiers in Genetics, 2019
Leukocyte adhesion deficiency-III (LAD3) is an extremely rare primary immunodeficiency disorder, transmitted with autosomal-recessive inheritance. It is caused by genetic alteration in the FERMT3 gene, which leads to abnormal expression of kindlin-3 ...
Saba Shahid, Samreen Zaidi, Shariq Ahmed, Saima Siddiqui, Aiysha Abid, Shabbir Malik, Tahir Shamsi   +6 more
doaj   +1 more source