Results 181 to 190 of about 181,318 (257)

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

Nonoperative Management of a T1 Spinous Process Apophyseal Stress Fracture in an Adolescent Baseball Pitcher: A Case Report. [PDF]

Int Med Case Rep J
Fukuda Y, Kato K, Otoshi K, Kaga T, Matsumoto Y.   +4 more
europepmc   +1 more source

Intrasplenic Thymus Organogenesis from Injectable Tissue Fragments Restores Functional T‐Cell Immunity

Advanced Science, EarlyView.
Clinical intramuscular thymus transplantation yields only short‐lived efficacy and marginal therapeutic benefits. Benefiting from the spleen's intrinsic strengths—rapid vascular perfusion, abundant developmental factors, and resident progenitors—the intrasplenic thymic grafts achieve robust thymic regeneration and substantial T‐cell reconstitution ...
Shaocong Wang, Zijian Zhang, Fulin Dai, Zhijie Yin, Zhen Xing, Yurong Li, Haochong Lei, Junfeng Zhang, Chunyan Liu, Yan Li, Lei Dong   +10 more
wiley   +1 more source

Macrophage PABPC4‐SPP1 Axis Orchestrates Immunosuppression in Colorectal Cancer

Advanced Science, EarlyView.
In the CRC microenvironment, macrophage PABPC4 binds to the 3′UTR of SPP1 mRNA to stabilize its expression, thereby sustaining M2‐like immunosuppressive macrophage polarization. Concurrently, this axis suppresses CD8+ T cell effector functions via CD44 signaling, collectively fostering an immunosuppressive niche that drives tumor progression.
Meng Wang, Fang Yang, Yuan Gao, Liuli Li, Yulan Huang, Hui Yao, Sijie Zhao, Kun Zhao, Tianying Zhang, Hui Heng, Jiaxin Xu, Yuancai Xiang, Weidong Xiao, Shaofan Hu, Hongming Miao   +14 more
wiley   +1 more source

Pseudo-negative serum protein electrophoresis due to IgM aggregation in a patient with Waldenström macroglobulinemia: A case report. [PDF]

Medicine (Baltimore)
Xie H, He E, Quan H, Zhang S.
europepmc   +1 more source

Emergency Cholecystectomy for Gangrenous Acute Cholecystitis with Profound Thrombocytopenia: Immune Thrombocytopenia Diagnosed Postoperatively. [PDF]

Surg Case Rep
Tokumaru T, Tabuchi M, Uemura S, Tamura S, Iriyoshi H, Imai T, Kakizaki M, Osawa S, Okabayashi T.   +8 more
europepmc   +1 more source

Trastuzumab deruxtecan treatment for HER2-low metastatic scrotal extramammary Paget's disease with bone marrow involvement: a case report. [PDF]

Front Oncol
Bao Y, Zhang L, Jiang F, Mo J.
europepmc   +1 more source

Severe aplastic anemia as a rare autoimmune complication of ankylosing spondylitis: A rare case report. [PDF]

Medicine (Baltimore)
Alkhen R, Alswij MA, Musleh M, Mohsen Y, ALHusein Q.   +4 more
europepmc   +1 more source

Chronic Recurrent Multifocal Osteomyelitis in a Pediatric Patient: An Uncommon Case With Diagnostic Challenge. [PDF]

Clin Case Rep
Regmi D, Bhattarai M, Bhandari S, Jha S, Baral A.   +4 more
europepmc   +1 more source