Results 101 to 110 of about 659,274 (352)

Improving outcomes of hematopoietic stem cell transplant for leukemia in children and young adults in resource-limited setting

Pediatric Hematology Oncology Journal
Introduction: Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative approach in patients with relapsed and high-risk leukemia. This retrospective analysis aimed to investigate outcomes and risk factors associated with HSCT in children ...
Garima Nirmal, Subhashish Paul, Vaibhav Chadha, Shreyasi Das, Mohit Chaudhary, Manju Joseph, Bharti Sharma, Himshikha Yadav, K.K. Swathymon, Iskandarov Kamol, Gaurav Kharya   +10 more
doaj   +1 more source

Bioengineered Lymphatic Vessels in Synthetic Matrices to Study Breast Cancer Cell Functions

Advanced Healthcare Materials, EarlyView.
Lymphatic vessels are involved in cancer metastasis. To study the interplay between metastasizing cancer cells and lymphatic vessels under highly reproducible conditions, advanced in vitro models are required. In this work, 3D lymphatic networks are formed in biomimetic hydrogels and their interactions with invasive and non‐invasive cancer cell‐lines ...
Rodi Odabasi, Lisa A. Krattiger, Magdalini Kanari, Mira A. Jacobs, Lukas O. Moser, Mark W. Tibbitt, Cornelia Halin, Martin Ehrbar   +7 more
wiley   +1 more source

OUTCOME OF CHEMOTHERAPY IN NON ACUTE PROMYELOCYTIC ACUTE MYELOID LEUKAEMIA

Pakistan Armed Forces Medical Journal, 2020
Objective: Retrospective analysis to evaluate overall response and outcome of various therapeutic regimens given in patients with non acute promyelocytic acute myeloid leukaemia (non APL AML). Study Design: Retrospective study.
Nighat Shahbaz, Parvez Ahmed, Tariq Mehmood Satti, Nadeem Paracha, Syed Kamran Mehmood, Qamar Un Nisa Chaudhary, Mehreen Ali Khan, Humayyun Satti   +7 more
doaj   +2 more sources

Platelet Lysate–Enriched Human Induced Pluripotent Stem Cell–Derived Chondrocyte Sheets for Bone Defect Repair via Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human iPSC‐derived hypertrophic chondrocyte sheet promotes bone regeneration. Abstract Bone defects are a major clinical challenge, primarily owing to the limited self‐healing capacity of bones and the high risk of complications associated with conventional treatment strategies.
Yiwei Chen, Jiali Lin, Jiapeng Li, Yiwei Hu, Jiansen Su, Yu Miao, Lanlan Wang, Qian Tang, Changqing Zhang, Junhui Yin   +9 more
wiley   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

Spatial Patterning of Modular Gelatin‐Peroxide Microspheres in Melt‐Electrowritten Scaffolds Provides Controlled Oxygen Generation and Mitigates Hypoxia and Cytotoxicity

Advanced Healthcare Materials, EarlyView.
A bioassembly approach is described using photo‐crosslinked gelatin‐based microgels containing calcium peroxide (CaO2) to generate oxygen (O2) and enhance cell survival in hypoxic conditions (1% O2). Bioassembly enables spatial patterning of individual CaO2‐laden and mesenchymal stem cell (MSC)‐laden microgels and allows for decoupling and mitigating ...
Axel E. Norberg, F. Max Yavitt, Ezgi Bakirci, Khoon Lim, Tim B. F. Woodfield, Gabriella C. J. Lindberg   +5 more
wiley   +1 more source

First 100 days outcomes of cryopreserved vs non-cryopreserved stem cells autologous bone marrow transplant in multiple myeloma - a single center experience

Khyber Medical University Journal
Objective: To compare the first 100 days' outcomes of autologous stem cell transplantation (Auto-BMT) using cryopreserved versus non-cryopreserved grafts in multiple myeloma (MM) patients.
Awais Siddiq, Mehreen Ali Khan, Jehanzeb Ur Rehman, Irsa Hidayat, , Qudratullah, Munazza Nabi Awan, Hammad Javed   +6 more
doaj   +1 more source

Graft-versus-host disease in children who have received a cord-blood or bone marrow transplant from an HLA-identical sibling. Eurocord and International Bone Marrow Transplant Registry Working Committee on Alternative Donor and Stem Cell Sources.

New England Journal of Medicine, 2000
V. Rocha, J. Wagner, K. Sobocinski, J. Klein, Mei-Jie Zhang, M. Horowitz, E. Gluckman   +6 more
semanticscholar   +1 more source

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory, Agathe C.M. Heyraud, Julian R. Jones, Sara M. Rankin   +3 more
wiley   +1 more source

Safety and Efficacy of Extracorporeal Photopheresis for Acute and Chronic Graft-versus-Host Disease

Pharmaceuticals
Background/Objectives: Despite novel biological agents, steroid-dependent or -refractory graft-versus-host disease (GvHD) remains a severe complication of allogeneic hematopoietic cell transplantation (allo-HCT).
Eleni Gavriilaki, Eleni Papchianou, Giorgos Karavalakis, Ioannis Batsis, Alkistis Panteliadou, Andriana Lazaridou, Despina Mallouri, Varnavas Constantinou, Paraskevi Karvouni, Paschalis Evangelidis, Anna Papakonstantinou, Apostolia Papalexandri, Panayotis Kaloyannidis, Nikolaos Spyridis, Zoi Bousiou, Anna Vardi, Evangelia Yannaki, Damianos Sotiropoulos, Ioanna Sakellari   +18 more
doaj   +1 more source