Results 151 to 160 of about 1,454,464 (291)

The Nuclear Receptor Testicular Receptor 4 Orchestrates Cytoskeletal Organization in a G Protein Subunit Alpha 12/Rho‐Associated Protein Kinase–Dependent Manner to Promote Myofibroblast Differentiation and Tissue Fibrosis in Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective Members of the superfamily of nuclear receptors have been implicated in inflammatory processes and pathologic tissue remodeling and have emerged as attractive targets for pharmaceutical intervention. However, the role of testicular receptor 4 (TR4; or Nr2c2) in fibroblast activation and rheumatologic diseases has not yet been investigated ...
Yun Zhang, Lichong Shen, Junhui Zheng, Gisela Baur, Dilidaer Yasen, Honglin Zhu, Yi‐Nan Li, Xianyi Meng, Thuong Trinh‐Minh, Tim Filla, Debomita Chakraborty, Andrea‐Hermina Györfi, Christina Bergmann, Adam Reich, Alexander Kreuter, Georg Schett, Jörg H. W. Distler   +16 more
wiley   +1 more source

Minnesota acute graft-versus-host disease risk score predicts survival at onset of graft-versus-host disease after post-transplant cyclophosphamide prophylaxis

Haematologica, 2022
Federica Ardizzoia, Francesca Lorentino, Alessandro Bruno, Sarah Marktel, Fabio Giglio, Daniela Clerici, Francesca Farina, Sara Mastaglio, Simona Piemontese, Andrea A. Assanelli, Matteo G. Carrabba, Massimo Bernardi, Consuelo Corti, Jacopo Peccatori, Fabio Ciceri, Raffaella Greco, Maria Teresa Lupo-Stanghellini   +16 more
doaj   +1 more source

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

Immune reset: what do we learn from bone marrow transplantation. [PDF]

Med Rev (2021)
Guo H, Huang XJ.
europepmc   +1 more source

Dnmt3a Mutations Limit Normal and Autoreactive CD4+ T Follicular Helper Responses and Attenuate T Cell–Driven Joint Inflammation

Arthritis &Rheumatology, EarlyView.
Objective Somatic DNMT3A mutations are the most common drivers of clonal hematopoiesis in patients with rheumatoid arthritis (RA) and have been associated with seropositive disease and increased markers of inflammation. These mutations are predominantly hypomorphic or dominant‐negative, reducing DNMT3A function.
Yunbing Shen, Sanjaykumar Boddul, Zhaojun Li, Zsolt Kasza, Marlene Schülein, Bruno Raposo, Karine Chemin, Per‐Johan Jakobsson, Alexander Espinosa, Lars Klareskog, Fredrik Wermeling   +10 more
wiley   +1 more source

Recovery of spermatogenesis following bone marrow transplantation. [PDF]

Haematologica
Daniele J, Savkovic S, Idan A, Zhang T, Jayadev V, Conway AJ, Handelsman DJ.   +6 more
europepmc   +1 more source

Dual‐Scaffold Technique: Autologous Minced Cartilage and Bone Marrow Aspirate Scaffold Combined With Synthetic Collagen Membrane for Cartilage Repair

Arthroscopy Techniques, EarlyView.
Abstract Treating cartilage injuries has long been a complex challenge; however, recent progress has greatly increased the variety of effective therapeutic approaches. The minced autologous matrix‐induced chondrogenesis plus procedure for full‐thickness knee cartilage lesions uses a collagen matrix combined with shaver‐minced cartilage graft and bone ...
Leonardo Ataíde, Moises Cohen, Pedro Debieux, Camila Cohen Kaleka, José Martins Juliano Eustáquio, Lucas Barbosa   +5 more
wiley   +1 more source

Eosinophilic Gastrointestinal Disease After Pediatric Organ and Bone Marrow Transplantation. [PDF]

JGH Open
Sinai E, Wilson BE, Pecak M, Schroeder S, Swing EL, Bauer C.   +5 more
europepmc   +1 more source

Arthroscopic Treatment of Focal Chondral Defects in the Hip Joint With Autologous Minced Cartilage, Allograft Cartilage Extracellular Matrix, and Platelet‐Rich Plasma

Arthroscopy Techniques, EarlyView.
Abstract Focal chondral defects (FCDs) are often encountered during hip arthroscopy for the treatment of femoroacetabular impingement. Historically, arthroscopic treatment for FCDs in the hip joint has revolved around microfracture, though recent evidence has showed inferior outcomes with this approach. Open cartilage repair procedures in the hip joint
Austin G. Cross, Ashley D. Price, Anthony J. Scillia, Matthew J. Kraeutler   +3 more
wiley   +1 more source

Secondary Pulmonary Alveolar Proteinosis Associated With Ruxolitinib After Bone-Marrow Transplantation: A Case With Transient Improvement Following Drug Discontinuation. [PDF]

Respirol Case Rep
Yanagi T, Asami-Noyama M, Yamamoto K, Hoshii Y, Ichiyama Y, Okimura M, Fujii T, Suizu J, Harada M, Murakawa K, Hamada K, Utsunomiya T, Murata Y, Oishi K, Edakuni N, Kakugawa T, Hirano T, Matsunaga K.   +17 more
europepmc   +1 more source