Results 171 to 180 of about 807,862 (404)

A controlled trial of fluconazole to prevent fungal infections in patients undergoing bone marrow transplantation.

open access: yesNew England Journal of Medicine, 1992
J. Goodman   +20 more
semanticscholar   +1 more source

Faecalibaculum rodentium Alleviates Ionizing Radiation‐Induced Damage in Mice by Improving Intestinal Integrity and Hematopoiesis via Its Metabolite Butyrate

open access: yesAdvanced Science, EarlyView.
The model shows the probiotics screening and underlying mechanisms of F. rodentiumn in alleviating IR‐induced tissue injury. Stress‐induced STAT3 mitochondria localization decreases F. rodentium abundance and butyrate concentration. Supplementation of F.
Hanyong Zhu   +17 more
wiley   +1 more source

Energy Deficiency‐Induced ATG4B Nuclear Translocation Inhibits PRMT1‐Mediated DNA Repair and Promotes Leukemia Progression

open access: yesAdvanced Science, EarlyView.
This study demonstrated that ATG4B translocates from the cytoplasm to the nucleus during energy deficiency. Nuclear ATG4B inhibits DNA repair by interacting with PRMT1. The nuclear ATG4B‐mediated DNA repair defect is significantly exacerbated within acute myeloid leukemia (AML) cells, promoting leukemia progression in an AML mouse model.
Zhenkun Wang   +20 more
wiley   +1 more source

Inhibition of Macrophage ARID3A Alleviates Myocardial Ischemia‐Reperfusion Injury After Heart Transplantation by Reducing THBS1/CD47 Signaling‐Mediated Neutrophil Extracellular Traps Formation

open access: yesAdvanced Science, EarlyView.
This study reveals that ARID3A in macrophages can transcriptionally regulate the THBS1‐CD47 axis after heart transplantation (HT), thereby inducing activated neutrophils to release NETs through the p38 MAPK signaling pathway. The itaconate derivative 4‐OI can inhibit ARID3A in macrophages and promote the accumulation of antioxidant factors, thereby ...
Hao Tian   +7 more
wiley   +1 more source

Bone marrow origin of endothelial progenitor cells responsible for postnatal vasculogenesis in physiological and pathological neovascularization.

open access: yesCirculation Research, 1999
T. Asahara   +8 more
semanticscholar   +1 more source

Targeting of the CD161 Inhibitory Receptor Enhances Bone‐Marrow‐Resident Memory CD8+ T‐Cell‐Mediated Immunity against Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
CD161 is identified as a novel inhibitory receptor on bone marrow (BM)‐resident CD8⁺ T cells in multiple myeloma (MM). Through interaction with its ligand CLEC2D, CD161 impairs T‐cell function and promotes immune suppression. Blockade of CD161 restores tissue residency and cytotoxicity of CD8⁺ T cells and enhances chimeric antigen receptor T‐cell (CAR ...
Liwen Wang   +16 more
wiley   +1 more source

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