Results 171 to 180 of about 823,617 (410)
VI Consensus of the Brazilian Society of Bone Marrow Transplantation (SBTMO) - Consensus on Graft-versus-Host Disease (GVHD)
, 2023 Vaneuza Araújo Moreira Funke, Maria Cláudia Rodrigues Moreira, Antônio Vaz de Macedo, Andresa Melo, Jayr Schmidt Filho, Giancarlo Fatobene, Rita de Cássia B. S. Tavares, Márcia M. Silva, M. C. M. A. Macedo, Marcos Paulo Colella, Vergílio Antônio Rensi Colturato, Mair Pedro de Souza, Morgani Rodrigues, João Victor Piccolo Feliciano, Luís Fernando S. Bouzas, Afonso Celso Vigorito +15 moreopenalex +2 more sourcesBiomimetic Nanomedicine for Senescence‐Modulated Immune Activation Enhances Immunotherapy Efficacy in Hepatocellular Carcinoma
Advanced Science, EarlyView.A multifunctional mPDZM nanoplatform is developed in this study. mPDZM integrates chemotherapy‐induced senescence, selective senolysis, and STING‐mediated immune activation. mPDZM effectively clears senescent tumor cells, remodels the tumor immune microenvironment, and enhances antitumor T‐cell responses.Shiji Fang, Liyun Zheng, Bin Lin, Jiale Chen, Dehai Hou, Yiming Ding, Mengzhu Han, Pan Qin, Mengyuan Wang, Xiaoju Guo, Yeyu Zhang, Gaofeng Shu, Fazong Wu, Jianfei Tu, Minjiang Chen, Zhongwei Zhao, Zhuang Liu, Jiansong Ji +17 morewiley +1 more sourceF13A1‐Mediated Macrophage Activation Promotes MASH Progression via the PKM2/HIF1A Pathway
Advanced Science, EarlyView.In fatty liver disease, hepatocytes exposed to palmitate release S1P, which activates calcium signaling in macrophages. Elevated calcium enhances the activity of F13A1, driving PKM2 dimerization. The PKM2 dimers cause Warburg effect, translocate to the nucleus, cooperate with HIF1A, and upregulate IL1B expression, ultimately promoting classical ...Qianrang Lu, Meiching Ong, Xuewen Yi, Muqiong Xing, Xinyao Tian, Ke Zhang, Ling Lu, Hao Wang, Xiaohan Lin, Jun Fang, Aibo Mu, Jiaying Cao, Jingyu Jiang, Feng Gao, Hongjun Li, Baohong Wang, Qi Ling +16 morewiley +1 more sourceThe mystique of organ transplantation [PDF]
, 2005 Bach, Barker, Barnard, Billingham, Billingham, Calne, Calne, Calne, Cordier, Doherty, Gatti, Gibson, Hamburger, Hamburger, Kuss, Küss, Main, Mannick, Medawar, Medawar, Merrill, Murray, Murray, Peacock, Phelps, Przepiorka, Shapiro, Shapiro, Simonsen, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Thomas, Thomas E. Starzl, Todo, Zinkernagel +48 morecore +1 more sourceEngineered Small Extracellular Vesicles Targeting Tumor‐Associated Endothelial Cells to Effectively Remodel the Glioma Microenvironment
Advanced Science, EarlyView.This study developed a novel drug delivery platform that overcomes the blood‐brain barrier in glioblastoma. By fusing IGFBP7 with small extracellular vesicles, the platform specifically targets tumor vasculature. It effectively delivers temozolomide, suppressing tumor growth at low doses.Lingling Liu, Feiyang Xu, Zhiming Zheng, Xiaodan Yang, Fang Yang, Pei Liu, Yuankun Chen, Yunshu Yang, Junli Zhao, Peiyan Yang, Xiaojing Zheng, Xiaohong Sun, Ping Mao, Qinwen Mao, Hao Guan, Haibin Xia, Weifeng Zhang, Dan Xiao +17 morewiley +1 more source