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Bone marrow transplantation

Critical Reviews in Oncology/Hematology, 1985
Bone marrow transplantation is increasingly used to treat a broad spectrum of human diseases including aplastic anemia, leukemia, solid tumors, immune and genetic disorders. In certain circumstances the role of transplantation is reasonably well established, such as aplastic anemia and resistant leukemia. In other circumstances there is controversey as
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Transplantation of Chimeric Bone Marrow

International Journal of Radiation Biology and Related Studies in Physics, Chemistry and Medicine, 1961
SummaryRetransplantation of bone marrow was studied in an attempt to understand why foetal liver was superior to adult bone marrow in the treatment of lethally-irradiated mice.Presensitization experiments, in which recipients were immunized against cells of the future donor-strain, were performed.
Vos, O, Goodman, J W, Congdon, C C
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Bone Marrow Purging for Autologous Bone Marrow Transplantation

Leukemia & Lymphoma, 1993
High dose therapy with the resulting myeloablation rescued by infusion of autologous bone marrow (ABMT) has become a major treatment option for an increasing number of patients with hematologic and solid tumors. ABMT has several potential advantages over allogeneic transplantation.
J G, Gribben, L M, Nadler
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Bone marrow transplantation for myeloblastoma

European Journal of Haematology, 1988
A 20‐yr‐old man with bulky mediastinal and retroperitoneal tumour masses identified as myeloblastoma is described. After a partial remission was induced by aggressive chemotherapy, mediastinal irradiation and retroperitoneal tumour resection, the patient received an allogeneic marrow graft from his HLA‐identical sister.
K, Quabeck   +7 more
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A History of Bone Marrow Transplantation

Immunology and Allergy Clinics of North America, 2010
The last 40 years has seen the emergence of hematopoietic stem cell transplantation as a therapeutic modality for fatal diseases and as a curative option for individuals born with inherited disorders that carry limited life expectancy and poor quality of life.
M Teresa, de la Morena, Richard A, Gatti
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Allogeneic Bone Marrow Transplantation

CRC Critical Reviews in Clinical Laboratory Sciences, 1983
Allogeneic bone marrow transplantation now has an established place in the treatment of severe aplastic anemia and acute leukemia. Major problems to be overcome in transplantation in patients with aplastic anemia are marrow graft rejection and graft vs. host disease.
Paul L. Weiden, John G. Batsakis
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Bone Marrow Transplantation

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1987
Since the 1970s major progress in bone marrow transplantation has resulted in long‐term survival and even cure for many patients with serious hematologic disease. Many patients undergoing the procedure, however, experience serious complications, including graft rejection, graft‐versus‐host disease, and infection.
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Bone marrow transplant in adrenoleukodystrophy

Neurology, 1984
An allogeneic bone marrow transplant (BMT) from a normal HLA identical sibling donor was performed in a 13-year-old boy with rapidly progressive adrenoleukodystrophy (ALD). Engraftment and complete hematologic recovery occurred within 4 weeks, but neurologic deterioration continued. The patient died of an adenovirus infection 141 days after BMT. ALD is
Hugo W. Moser   +13 more
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Hyperuricemia and Bone Marrow Transplantation

2004
Blood uric acid levels and purine metabolism are affected in many ways after bone marrow transplantation (BMT). Although BMT is usually performed when patients have a low residual disease burden, a proportion of them are still at risk of tumor lysis syndrome, even with limited disease or after nonmyeloablative conditioning regimens; moreover, an ...
Giorgio Lambertenghi, Deliliers   +1 more
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Autologous Bone Marrow Transplantation

Annual Review of Medicine, 1989
Autologous bone marrow transplantation in the acute leukemias and lymphomas offers potentially curative treatment in patients who do not have a histocompatible, allogeneic donor. Results of marrow autografting in the lymphomas are especially encouraging, with disease-free survivals of 50-60% in patients who have failed primary and secondary treatment ...
G W, Santos, A M, Yeager, R J, Jones
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