Results 151 to 160 of about 2,226,476 (263)

In Situ Stress‐Dispersing Hydrogel Millispheres via Load Redistribution to Restore Nucleus Pulposus Metabolic Homeostasis

Advanced Science, EarlyView.
Local stress concentration disrupts metabolic homeostasis and induces inflammation in the nucleus pulposus (NP), thereby accelerating intervertebral disc degeneration (IDD). A biomimetic HA/ChS hydrogel millimeter sphere (ChS@HM) is developed to enable synergistic stress dispersion and sustained hydration lubrication.
Ang Li, Hui Yuan, Honglei Xiao, Xiaodong Liu, Wenguo Cui   +4 more
wiley   +1 more source

The influence of hormonal changes during pregnancy on bone metabolism - a mini review. [PDF]

Front Endocrinol (Lausanne)
Brona A, Stachowska B, Bolanowski M, Halupczok-Żyła J.   +3 more
europepmc   +1 more source

Strategy of Triple‐Gradient in Binary Pixels for Flexible Pressure Sensing with High Sensitivity and Wide‐Range Linearity

Advanced Science, EarlyView.
A flexible pressure sensor with triple‐gradient design of conductivity, modulus, and dimension in binary micro‐dome pixels is proposed. Based on precisely‐designed CNT/PDMS matrix, the device exhibits a linear sensitivity of 974.1 kPa−1 across range up to 1.8 MPa (R2 > 0.99), offering an effective strategy for potential applications in healthcare ...
Yifan Liu, Xiao Xu, Fengming Hu, Yuanzhe Liang, Zidong Yin, Biao Qi, Ruolin Liu, Ziyi Dai, Jianyi Luo, Bingpu Zhou   +9 more
wiley   +1 more source

Homocysteine and bone metabolism markers in osteoporotic patients: A secondary analysis. [PDF]

Medicine (Baltimore)
Li W, Wu H, Lu T, Pan R, Deng X, Lai K, Su X, Zhuo Z, Wu S, Li M.   +9 more
europepmc   +1 more source

A Rare De Novo Missense Mutation in IFT122 Confers a Genetic Susceptibility Factor of Idiopathic Pediatric Uveitis Via Trio‐based Whole‐Exome Sequencing

Advanced Science, EarlyView.
A rare de novo IFT122‐A773E variant is identified in idiopathic pediatric uveitis and shown to exacerbate retinal inflammation and barrier dysfunction. Mechanistically, the variant enhances IFT43 interaction, elevates calcium signaling, and activates the MEK/ERK/FRA1 axis, revealing a previously unrecognized cilia‐associated pathway that may increase ...
Qian Zhou, Jiaxing Huang, Yilin Wang, Xingran Li, Xianyang Liu, Lingyu Dai, Hongshun Li, Qingfeng Wang, Jiangyi Liu, Guannan Su, Wanyun Zhang, Yang Deng, Qingfeng Cao, Yujie Lai, Xiang Luo, Changwei Huang, Ling Chen, Shengping Hou, Peizeng Yang   +18 more
wiley   +1 more source

Copper homeostasis and organelle-dependent mechanisms in bone metabolism: implications for osteoporosis therapy. [PDF]

Front Cell Dev Biol
Jiang J, Lin J, Zhou Z, Pan H, Zhao P, Ma D.   +5 more
europepmc   +1 more source

Effects of liver-derived insulin-like growth factor I on bone metabolism in mice

, 2002
Insulin-like growth factor (IGF) I is an important regulator of both skeletal growth and adult bone metabolism. To better understand the relative importance of systemic IGF-I versus locally expressed IGF-I we have developed a transgenic mouse model with ...
Liu, Jun-Li, Ohlsson, Claes,, Törnell, Jan,, Wallenius, Kristina,, Isaksson, Olle,, Jansson, John-Olov,, Mohan, Subburaman, Movérare, Sofia,, Sjögren, Klara,, Sheng, Matilda   +9 more
core  

A pH‐Switchable Cerium Single‐Atom Enzyme for Peri‐Implantitis Therapy via JAK‐STAT Signaling Axis‐Mediated Macrophage Reprogramming

Advanced Science, EarlyView.
A pH‐switchable cerium single‐atom enzyme is developed for stage‐specific peri‐implantitis therapy. Acidic conditions trigger antibacterial peroxidase‐like activity, whereas neutral conditions activate an antioxidant superoxide dismutase ‐ and catalase ‐like enzymatic relay. This microenvironment‐adaptive catalytic strategy suppresses the IL‐6/JAK‐STAT
Xiaomin Xia, Haojie Wu, Xingyun Li, Lining Liu, Kaiqing Song, Jinpei Cui, Jie Liu, Jiaxuan Yin, Emtiaz Ahmed, Yusuke Yamauchi, Xue Li   +10 more
wiley   +1 more source

Microtubule actin crosslinking factor 1 functions as a novel therapeutic target in lung metastasis of osteosarcoma

Genes and Diseases, 2023
Chaofei Yang, Ye Tian, Fan Zhao, Qian Huang, Zhiyong Liu, Chenyang He, Hui Li, Yu li, Zhiping Miao, Airong Qian   +9 more
doaj   +1 more source

Effects of Prediabetes on Bone Metabolism and Healing in Orthognathic Surgery: A Narrative Review. [PDF]

Eur J Dent
Siriwechadaruk S, Powcharoen W, Tripuwabhrut K, Imerb N.   +3 more
europepmc   +1 more source