Results 211 to 220 of about 366,647 (265)
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Bone metabolism in galactosemia
Bone, 2004Classical galactosemia is an autosomal recessively inherited disorder of galactose metabolism. Treatment consists of life-long dietary restriction of galactose. Despite treatment, long-term complications occur such as a decreased bone mineral density (BMD).
Panis, B. +6 more
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The metabolism and immunology of bone
Seminars in Arthritis and Rheumatism, 1989Many cells and their cytokines produce a significant effect on bone metabolism. Bone matrix synthesis is a function of the osteoblast (Fig 1), influenced directly by numerous local and systemic factors (Tables 1 and 2). Locally synthesized factors such as SGF, BMP, and BDGF may be particularly important in stimulating new bone formation at sites of ...
D A, Watrous, B S, Andrews
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Clinics in Podiatric Medicine and Surgery, 2022
Bone metabolism in the healthy, young adult is identified as a relatively stable process. Normal bone turnover is a dynamic state, which is conferred through intracellular signaling and complex cellular pathways. It has been well described in the literature that Charcot neuro-osteoarthropathy is a disease state, which is marked by intense bone turnover
Lisa, Grant-McDonald, William, Grant
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Bone metabolism in the healthy, young adult is identified as a relatively stable process. Normal bone turnover is a dynamic state, which is conferred through intracellular signaling and complex cellular pathways. It has been well described in the literature that Charcot neuro-osteoarthropathy is a disease state, which is marked by intense bone turnover
Lisa, Grant-McDonald, William, Grant
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Orvosi Hetilap, 2011
In the past decade several novel findings point to the critical role of the skeleton in several homeostatic processes, including energy balance. The connection begins in the bone marrow with lineage allocation of mesenchymal stem cells to adipocytes or osteoblasts. Osteoblasts and adipocytes produce factors affecting insulin homeostasis.
Eva, Ruzicska, Gyula, Poór
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In the past decade several novel findings point to the critical role of the skeleton in several homeostatic processes, including energy balance. The connection begins in the bone marrow with lineage allocation of mesenchymal stem cells to adipocytes or osteoblasts. Osteoblasts and adipocytes produce factors affecting insulin homeostasis.
Eva, Ruzicska, Gyula, Poór
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Oral Diseases, 2006
3‐Hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors (statins) are potent inhibitors of cholesterol biosynthesis. Cholesterol‐lowering therapy using statins significantly reduces the risk of coronary heart disease. However, extensive use of statins leads to increases of other undesirable as well as beneficial effects, so‐called pleiotropic ...
N, Horiuchi, T, Maeda
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3‐Hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors (statins) are potent inhibitors of cholesterol biosynthesis. Cholesterol‐lowering therapy using statins significantly reduces the risk of coronary heart disease. However, extensive use of statins leads to increases of other undesirable as well as beneficial effects, so‐called pleiotropic ...
N, Horiuchi, T, Maeda
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Comprehensive Physiology, 2023
Abstract Changes in bone architecture and metabolism with aging increase the likelihood of osteoporosis and fracture. Age‐onset osteoporosis is multifactorial, with contributory extrinsic and intrinsic factors including certain medical problems, specific prescription drugs, estrogen loss, secondary ...
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Abstract Changes in bone architecture and metabolism with aging increase the likelihood of osteoporosis and fracture. Age‐onset osteoporosis is multifactorial, with contributory extrinsic and intrinsic factors including certain medical problems, specific prescription drugs, estrogen loss, secondary ...
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Journal of Nephrology, 2004
Abstract Leptin is a hormone involved with satiety and energy balance and proposed to be an anti-obesity factor. Much effort has been dedicated to the relationship between leptin and bone. This interest stems from the knowledge that body weight is a major determinant of bone density.
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Abstract Leptin is a hormone involved with satiety and energy balance and proposed to be an anti-obesity factor. Much effort has been dedicated to the relationship between leptin and bone. This interest stems from the knowledge that body weight is a major determinant of bone density.
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JAMA: The Journal of the American Medical Association, 1979
ABSTRACT The second volume of Metabolic Bone Disease contains seven additional essays on bone and mineral metabolism. Despite the book's title, there is in many instances a scarcity of information on bone disease. Topics previously covered in the first volume do, however, make up for this deficit to some extent.The chapter on parathyroid physiology and
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ABSTRACT The second volume of Metabolic Bone Disease contains seven additional essays on bone and mineral metabolism. Despite the book's title, there is in many instances a scarcity of information on bone disease. Topics previously covered in the first volume do, however, make up for this deficit to some extent.The chapter on parathyroid physiology and
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Emergency Medicine Clinics of North America, 2005
Although bones are normally thought of as supporting structures that fracture when one falls, bone is actually a very active metabolic organ. It is vital in the regulation of calcium and phosphate metabolism, magnesium storage, and in buffering metabolic acido-sis. Bone and mineral metabolism and some of their disorders are presented in this article.
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Although bones are normally thought of as supporting structures that fracture when one falls, bone is actually a very active metabolic organ. It is vital in the regulation of calcium and phosphate metabolism, magnesium storage, and in buffering metabolic acido-sis. Bone and mineral metabolism and some of their disorders are presented in this article.
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Primary Care: Clinics in Office Practice
Metabolic bone diseases encompass a group of disorders characterized by abnormalities in bone metabolism, structure, or mineralization. These disorders negatively impact overall health and quality of life and place individuals at high risk for fracture, which may increase morbidity and mortality.
LaRae L, Seemann +2 more
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Metabolic bone diseases encompass a group of disorders characterized by abnormalities in bone metabolism, structure, or mineralization. These disorders negatively impact overall health and quality of life and place individuals at high risk for fracture, which may increase morbidity and mortality.
LaRae L, Seemann +2 more
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