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Primary Care: Clinics in Office Practice
Metabolic bone diseases encompass a group of disorders characterized by abnormalities in bone metabolism, structure, or mineralization. These disorders negatively impact overall health and quality of life and place individuals at high risk for fracture, which may increase morbidity and mortality.
LaRae L, Seemann +2 more
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Metabolic bone diseases encompass a group of disorders characterized by abnormalities in bone metabolism, structure, or mineralization. These disorders negatively impact overall health and quality of life and place individuals at high risk for fracture, which may increase morbidity and mortality.
LaRae L, Seemann +2 more
openaire +2 more sources
Oral Diseases, 2006
3‐Hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors (statins) are potent inhibitors of cholesterol biosynthesis. Cholesterol‐lowering therapy using statins significantly reduces the risk of coronary heart disease. However, extensive use of statins leads to increases of other undesirable as well as beneficial effects, so‐called pleiotropic ...
N, Horiuchi, T, Maeda
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3‐Hydroxy‐3‐methylglutaryl coenzyme A reductase inhibitors (statins) are potent inhibitors of cholesterol biosynthesis. Cholesterol‐lowering therapy using statins significantly reduces the risk of coronary heart disease. However, extensive use of statins leads to increases of other undesirable as well as beneficial effects, so‐called pleiotropic ...
N, Horiuchi, T, Maeda
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Current Opinion in Rheumatology, 1995
A suitable marker of bone metabolism is either a measurable enzymatic activity specific for osteoblasts or osteoclasts or a bone matrix component released into the circulation and excreted in the urine during bone formation or bone resorption. Testing such bone markers is the most sensitive method for monitoring acute changes in bone metabolism ...
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A suitable marker of bone metabolism is either a measurable enzymatic activity specific for osteoblasts or osteoclasts or a bone matrix component released into the circulation and excreted in the urine during bone formation or bone resorption. Testing such bone markers is the most sensitive method for monitoring acute changes in bone metabolism ...
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Structure and Metabolism of Bone
Medicine, 2001Abstract Bones provide mechanical support for joints, tendons and ligaments, protect vital organs, and act as a reservoir for calcium and phosphate in the preservation of normal mineral homeostasis. Bone is a complex and dynamic tissue that undergoes renewal and repair throughout life as the result of bone remodelling.
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Joint Bone Spine, 2005
The gradual reductions in bone mass and skeletal calcium density seen throughout adulthood occur in parallel with changes in the production of bioactive sex hormones in both men and women. The long-held belief that osteoporosis is dependent on androgens in men and estrogens in women has been challenged by recent reports of osteoporosis in young men ...
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The gradual reductions in bone mass and skeletal calcium density seen throughout adulthood occur in parallel with changes in the production of bioactive sex hormones in both men and women. The long-held belief that osteoporosis is dependent on androgens in men and estrogens in women has been challenged by recent reports of osteoporosis in young men ...
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Journal of Bone and Mineral Metabolism, 2012
Menin, a product of the MEN1 gene, is related to the ontogeny of several cancers such as MEN1 and sporadic endocrine tumors, although it is considered to be a tumor suppressor. Many proteins interact with menin, and it is involved in various biological functions in several tissues.
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Menin, a product of the MEN1 gene, is related to the ontogeny of several cancers such as MEN1 and sporadic endocrine tumors, although it is considered to be a tumor suppressor. Many proteins interact with menin, and it is involved in various biological functions in several tissues.
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Comprehensive Physiology, 2023
Abstract Changes in bone architecture and metabolism with aging increase the likelihood of osteoporosis and fracture. Age‐onset osteoporosis is multifactorial, with contributory extrinsic and intrinsic factors including certain medical problems, specific prescription drugs, estrogen loss, secondary ...
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Abstract Changes in bone architecture and metabolism with aging increase the likelihood of osteoporosis and fracture. Age‐onset osteoporosis is multifactorial, with contributory extrinsic and intrinsic factors including certain medical problems, specific prescription drugs, estrogen loss, secondary ...
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[Nutrition and bone metabolism].
Annales d'endocrinologie, 2006L’espérance de vie dans le monde occidental est passée en un siècle de 47 à 79 ans, et atteindra probablement 85 ans en 2010. Ce phénomène est également observé dans les pays en voie de développement, ce qui génère une transformation progressive de la population planétaire.
Coxam, Véronique, Davicco, Marie-Jeanne
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The role of autophagy in bone metabolism and clinical significance
Autophagy, 2023Xin Wang, Lan Xiao, Yin Xiao
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The crosstalk between bone remodeling and energy metabolism: A translational perspective
Cell Metabolism, 2022Sundeep Khosla, Gérard Karsenty
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