Results 81 to 90 of about 383,988 (266)

Changes in real-world walking speed following 60-day bed-rest

npj Microgravity
The aim of this work was to explore whether real-world walking speed (RWS) would change as a consequence of 60-day bed-rest. The main hypothesis was that daily RWS would decrease after the bed-rest, with a subsequent recovery during the first days of re ...
Marcello Grassi, Fiona Von Der Straten, Charlotte Pearce, Jessica Lee, Marcin Mider, Uwe Mittag, Wolfram Sies, Edwin Mulder, Martin Daumer, Jörn Rittweger   +9 more
doaj   +1 more source

Baicalein Attenuates Disuse-Driven Skeletal Senescence in Association with Gut Microbiota Modulation

Molecules
The progression of skeletal senescence under mechanical unloading conditions elevates fracture risk, emerging as a critical health challenge for the general population and astronauts during spaceflight.
Xin Zhao, Tingting Ren, Wei Bai, Hong Wang, Siddiq Ur Rahman, Xiaoni Deng, Kang Ru, Genyang Zhang, Wenjuan Zhang, Airong Qian   +9 more
doaj   +1 more source

The metabolism of bone marrow [PDF]

Biochemical Journal, 1938
J W, Orr, L H, Stickland
openaire   +2 more sources

A Magneto‐Mechanically Activated Nerve Guidance Conduit Promotes Peripheral Nerve Regeneration via TIMP1‐Mediated Membrane Tension Transfer

Advanced Functional Materials, EarlyView.
This study presents a magneto‐mechanical strategy that incorporates FP@MSCs into an aligned PCL/GelMA nerve guidance conduit. Magnetic stimulation increases membrane tension in FP@MSCs, triggering cytoskeletal remodeling, Schwann cell‐like differentiation, and TIMP1 secretion. TIMP1 activates ITGB1/CD63–FAK signaling in NE‐4C cells, increasing membrane
Xinyu Zhu, Yumin Wu, Xiang Gao, Tianlu Wang, Wanting Jia, Xueying Mei, Huanzhong Ji, Zongxi Wu, Yujie Liang, Xiang Li, Kan Li, Jingyuan Li, Guangsen Zheng, Guiqing Liao, Siyong Gao   +14 more
wiley   +1 more source

Unique Role of Microstructure of a Bioimplant Zinc Alloy and Protein Content of Simulated Body Fluid in Corrosion and Fracture

Advanced Functional Materials, EarlyView.
BSA addition to physiological solutions enhances resistance of a Zn alloy to stress corrosion cracking (SCC) but reduces its corrosion resistance. Extended surface characterization explains the contrasting influences on corrosion and SCC. Unexpectedly, the alloy suffers transgranular SCC (TGSCC), despite extensive grain boundary precipitation. Thorough
RK Singh Raman, Syed Hussain Wajahat, Saad Al‐Saadi, Robin E. Schäublin, Peng Zeng, Solomon Ansah, Jixing Lin, Xian Tong, Cuie Wen, Jörg F. Löffler   +9 more
wiley   +1 more source

Hydroxytyrosol acetate increases oxidative stress and proinflammation in young but not aged mice

Journal of Nutrition & Intermediary Metabolism, 2017
J.H. Ma, F. Zhao, Y.Y. Wang, X.L. Ma, W.X. Qiu, A.R. Qian   +5 more
doaj   +1 more source

A New Bioactive Glass‐Based Hybrid Bioink With Enhanced Cell Viability and Antibacterial Properties

Advanced Healthcare Materials, EarlyView.
Graphical illustration of the production and characterization process, demonstrating the multiple functions of the new hybrid gelatin methacryloyl‐silver‐bioactive glass (GAB) material. Created in https://BioRender.com. ABSTRACT Recent advances in three‐dimensional bioprinting (3DBP) technology enable the production of customized bone substitutes ...
Adam C. Marsh, Ehsanul Hoque Apu, Theofania Kleisoura, Romila Manchanda, Valerie Johnson, Ginger Ross, Ioannis Tsamesidis, Eleana Kontonasaki, DeMarcus Bunn, Ahmet Erdem, Neal D. Hammer, Kurt D. Hankenson, Christopher H. Contag, Nureddin Ashammakhi, Xanthippi Chatzistavrou   +14 more
wiley   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

Advanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei, Hesam Mohammadi, Shamim Golafshan, Mojtaba Alehosseini, Mahsa Mohammadzadeh, Atefeh Golshirazi, Nasim Golafshan, Tatiane Eufrásio‐da‐Silva, Alireza Dolatshahi‐Pirouz, Gorka Orive   +9 more
wiley   +1 more source

Author Correction: Combination of IL-6 and sIL-6R differentially regulate varying levels of RANKL-induced osteoclastogenesis through NF-κB, ERK and JNK signaling pathways

Scientific Reports, 2022
Wei Feng, Hongrui Liu, Tingting Luo, Di Liu, Juan Du, Jing Sun, Wei Wang, Xiuchun Han, Kaiyun Yang, Jie Guo, Norio Amizuka, Minqi Li   +11 more
doaj   +1 more source

CDK12 mediates the inhibition effect of mechanical unloading on osteoblast proliferation by regulating RNAPII transcription activation

Bone & Joint Research
Aims: Mechanical stimuli are crucial in regulating normal osteoblast function to maintain bone homeostasis. Decreased osteoblast proliferation is one of the main causes of osteoporosis induced by mechanical unloading.
Lifang Hu, Wenjin Zhong, Linlin Wang, Shujing Liang, Yunxian Jia, Zixiang Wu, Jingran Shen, Jiajun Sun, Airong Qian   +8 more
doaj   +1 more source