Results 211 to 220 of about 381,513 (352)

Ubiquitination‐Driven Reprogramming of Proteostasis in Metastasis

Advanced Science, EarlyView.
The DCAF12–TRiC/CCT axis is a key regulator of metastasis in cancer. By reprogramming proteostasis to ensure efficient protein folding, it drives progression through a dual mechanism: enhancing cancer cell motility and invasiveness while concurrently activating pro‐growth and survival pathways.
Dongping Wei, Jiayan Chen, Yaping Xu
wiley   +1 more source

Supplementary Data 2 from Genomic Analysis of a Spontaneous Model of Breast Cancer Metastasis to Bone Reveals a Role for the Extracellular Matrix¹

, 2023
Bedrich L. Eckhardt, Belinda S. Parker, Ryan K. van Laar, Christina M. Restall, Anthony Natoli, Michael D. Tavaria, Kym L. Stanley, Erica K. Sloan, Jane M. Moseley, Robin L. Anderson   +9 more
openalex   +1 more source

Modulation of Network Plasticity Opens Novel Therapeutic Possibilities in Cancer, Diabetes, and Neurodegeneration

Advanced Science, EarlyView.
Plasticity changes of molecular networks form a cellular learning process. Signaling network plasticity promotes cancer, metastasis, and drug resistance development. 55 plasticity‐related cancer drug targets are listed (20 having already approved drugs, 9 investigational drugs, and 26 being drug target candidates).
Márk Kerestély, István Narozsny, Levente Szarka, Daniel V. Veres, Peter Csermely, Dávid Keresztes   +5 more
wiley   +1 more source

A Cross-Sectional Study on the Status of Female Lung Cancer Patients With Bone Metastasis With or Without Osteoporosis. [PDF]

Health Sci Rep
Luo P, Liao X, Chen Y, Fu M.
europepmc   +1 more source

Malignant eccrine acrospiroma with nodal and bone metastasis

, 2016
Burhan Wani, Shiekh Aejaz Aziz, Mohmad Hussain Mir, Gull Mohammad Bhat, Abdul Rashid Lone   +4 more
openalex   +1 more source

Supplementary Table VI from Therapeutic Targeting of CD146/MCAM Reduces Bone Metastasis in Prostate Cancer

, 2023
Eugenio Zoni, Letizia Astrologo, Charlotte K.Y. Ng, Salvatore Piscuoglio, Janine Melsen, Joël Grosjean, Irena Klima, Lanpeng Chen, B. Ewa Snaar‐Jagalska, Kenneth Flanagan, Gabri van der Pluijm, Peter Kloen, Marco Cecchini, Marianna Kruithof‐de Julio, George N. Thalmann   +14 more
openalex   +1 more source

CXC Chemokine‐Driven Vascular Reprogramming: Modulating Tumor Vasculature to Boost Therapeutic Response

Advanced Science, EarlyView.
Tumor vascular remodeling is discussed from a chemokine‐centered perspective. This review summarizes the bidirectional, temporal, and tissue‐specific roles of CXC chemokines in regulating vascular function and immune accessibility. A functional vascular normalization score is introduced as a conceptual framework to integrate dynamic vascular and immune
Hongdan Chen, Yinde Huang, Juntong Wu, Ziying Yi, Yao Li, Zeyu Yang, Fan Zhang, Chong Li   +7 more
wiley   +1 more source

Astragalin Attenuates Bone Destruction and the Progression of Bone Metastasis in Breast Cancer. [PDF]

Cancers (Basel)
Yang S, Zhang Y, Qiu H, Hu X, Chu T.
europepmc   +1 more source

¹⁸F-Sodium Fluoride PET: History, Technical Feasibility, Mechanism of Action, Normal Biodistribution, and Diagnostic Performance in Bone Metastasis Detection Compared with Other Imaging Modalities [PDF]

, 2019
Kriti Ahuja, Houman Sotoudeh, Samuel J. Galgano, Ramandeep Singh, Nishant Gupta, Siddhartha Gaddamanugu, Gagandeep Choudhary   +6 more
openalex   +1 more source

Cholesterol Promotes Lung Adenocarcinoma Brain Metastasis by Stabilizing EGFR Protein to Drive EMT, Metabolic Reprogramming, and Premetastatic Niche Formation

Advanced Science, EarlyView.
Cholesterol is revealed as a multitasking fuel for lung adenocarcinoma brain metastasis: it locks EGFR at the membrane to sustain AKT/NF‐κB–driven glycolysis and EMT, loosens the blood–brain barrier by promoting Claudin‐5 loss, and rewires microglia through IL‐4R lipid‐raft–JAK1/STAT6 signaling.
Ying Chen, Xiaoteng Cui, Xinyi Shi, Xu Yang, Yujing Cao, Haolin LI, Qi Zhan, Qixue Wang, Ang Li, Qihong Cheng, Yunfei Wang, Junhu Zhou, MingJie Wang, Chunsheng Kang, Xiaomin Liu   +14 more
wiley   +1 more source