Results 141 to 150 of about 21,763 (267)

Collagen Type VI Alpha 1 as a Regulator of Redox Homeostasis in Antioxidant‐Enhanced Osteogenesis of Dental Stem Cells

Cell Proliferation, EarlyView.
Under physiological conditions, NAC activates the PI3K‐AKT‐COL6A1 axis to sustain redox balance and enhance osteogenesis. COL6A1 deficiency, however, compromises this axis, inducing oxidative stress and impairing NAC's osteogenic efficacy. ABSTRACT Alveolar bone injury represents a prevalent clinical challenge in dentistry, for which stem cell‐based ...
Zhaosong Meng, Jiacheng Liu, Yue Zhang, Ruimeng Yang, Jingyi Zhang, Haosun Yang, Zheng Wang, Ran Wei, Zhe Li, Shuling Guo, Lizhi Hu, Lei Sui   +11 more
wiley   +1 more source

Trabecular bone microarchitecture from μCT assessment of the tooth extraction sockets along the bone healing process.

, 2015
Morphological parameters of the trabecular bone microarchitecture were assessed using the CTAn software from the cylindrical region of interest (ROI) determined by segmenting the trabecular bone located from the coronal to apical thirds.
Claudia Cristina Biguetti (747150), Gustavo Pompermaier Garlet (78654), Rumio Taga (747153), Andreia Espindola Vieira (347874), Samuel de Barros Ferreira Junior (747148), Gerson Francisco Assis (747152), Rodrigo Cardoso Oliveira (747151), Priscila Maria Colavite (747149), Ana Paula Favaro Trombone (347882), Carlos Eduardo Repeke (347870)   +9 more
core   +1 more source

Update on the utility of trabecular bone score (TBS) in clinical practice for the management of osteoporosis: a systematic review by the Egyptian Academy of Bone and Muscle Health

Egyptian Rheumatology and Rehabilitation
Trabecular bone score (TBS) is a grayscale textural assessment resulting from a computed evaluation of pixel gray-level variations in previously obtained lumbar spine DXA images. It is an index of bone microarchitecture correlated with parameters of bone
Yasser El Miedany, Walaa Elwakil, Mohammed Hassan Abu-Zaid, Safaa Mahran   +3 more
doaj   +1 more source

YTHDF3 Enhances Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in Osteoporosis by Promoting TBX19 Expression

Cell Proliferation, EarlyView.
In this study, OP‐BMSCs were successfully isolated from OVX osteoporotic rats. Mechanistic investigations revealed that the RNA‐binding protein YTHDF3 significantly upregulates Tbx19 expression by enhancing the stability of Tbx19 mRNA. Elevated Tbx19 levels, in turn, activate key osteogenic molecules, effectively promoting the differentiation of OP ...
Qianke Tao, Qiaonan Ye, Chengpeng Yang, Yuping Xie, Xuemei Long, Long Bai, Zhiyuan Zhang, Qianwei Li, Dan Tan, Jingang Xiao   +9 more
wiley   +1 more source

Screening for bone health in older people with HIV: Uptake and outcomes from a large UK outpatient HIV service

HIV Medicine, EarlyView.
Abstract Objectives Bone health is negatively affected in people with HIV, and the risks of osteoporosis and fragility fractures are increased. The objective of this study was to describe the characteristics of those accessing bone health screening and identify factors associated with osteoporosis.
Rhys Nicholas, Kate Alford, Colin Fitzpatrick, Jaime Vera   +3 more
wiley   +1 more source

Bone health in adults with non‐ambulatory neuromuscular disorders: scoping review of risk factors, diagnosis and management

Internal Medicine Journal, EarlyView.
Abstract Background Non‐ambulatory adults have an increased risk of osteoporosis and fractures due to reduced weight‐bearing and diminished neuromuscular stimulation, resulting in substantial morbidity and mortality. Aims This scoping review aimed to systematically evaluate risk factors, diagnostic indicators and management strategies for optimising ...
Thomas Bailey, Carolyn Droste, John A. Eisman, Steven G. Faux, Arnagretta Hunter   +4 more
wiley   +1 more source

Changes in bone density and microarchitecture in adolescents undergoing a first kidney transplantation: a prospective study

International audienceAbstract Purpose Mineral bone disorder associated with chronic kidney disease (CKD-MBD) frequently persists after kidney transplantation (KTx), being due to pre-existing CKD-MBD, immunosuppressive therapies, and post-KTx ...
Leclerc, Anne-Laure Sellier, Confavreux, Cyrille, Aurelle, Manon, Levi, Charlène, Bacchetta, Justine, de Mul, Aurélie, Ginhoux, Tiphanie, Portefaix, Aurélie   +7 more
core   +1 more source

Advancing collagen‐related pathology assessment through second‐harmonic generation imaging

Journal of Microscopy, EarlyView.
Abstract Collagen remodelling and dysregulation are the hallmarks of diverse pathological conditions. In this context, second‐harmonic generation (SHG) imaging has emerged as a powerful label‐free modality for assessing collagen. This offers submicron resolution, intrinsic optical sectioning, and deeper imaging capabilities without the need for ...
Jackson Rodrigues, Manikanth Karnati, Gagan Raju, Edwin Pious, Ankur Gogoi, Guan‐Yu Zhuo, Nirmal Mazumder, Fu‐Jen Kao   +7 more
wiley   +1 more source

High-resolution peripheral quantitative CT of the proximal fifth metatarsal reveals microstructural similarity between Lawrence and Botte zones I and II

Bone & Joint Research
Aims: The optimal treatment of proximal fifth metatarsal (MT-V) fractures remains controversial. The most commonly used classification according to Lawrence and Botte distinguishes between three fracture types (zone I to III, from proximal to distal ...
Lara Krüger, Ali Hedar, Tanja Spethmann, Benjamin Ondruschka, Frank Timo Beil, Felix von Brackel, Alexander Simon, Tim Rolvien   +7 more
doaj   +1 more source

Scaling relationships between Haversian canal‐to‐secondary osteon and midshaft femur cortical‐to‐total area in a human autopsy sample

Journal of Anatomy, EarlyView.
We report that femoral cortical thickness was strongly and negatively associated with secondary osteon porosity in an Australian autopsy sample, indicating that thicker cortices contained less porous secondary osteons. This allometric relationship held for the whole sample, males and sedentary well‐nourished individuals, but not for females or other ...
Justyna J. Miszkiewicz, Laura A. B. Wilson, Karen M. Cooke, Rita Hardiman   +3 more
wiley   +1 more source