Treadmill Exercise Enhances the Effects of Zoledronate on Bone Microarchitecture and Mechanical Strength in Ovariectomized Rat Model of Osteoporosis. [PDF]
Tsubouchi Y +6 more
europepmc +1 more source
ABSTRACT Extracellular vesicles (EVs) are nanosized lipid bilayer particles naturally secreted by cells, mediating intercellular communication and transporting diverse bioactive molecules. Among alternative EV sources, bovine milk‐derived EVs (BMEVs) have emerged as promising platforms for drug delivery due to their accessibility, scalability ...
Martina Brattini +3 more
wiley +1 more source
Effect of thyrotropin suppression therapy on bone microarchitecture in postoperative patients with differentiated thyroid cancer. [PDF]
Chen Z +7 more
europepmc +1 more source
Podocyte mPGES‐2 Determines Renal Aging and Contributes to Senile Osteoporosis
Podocyte mPGES‐2 drives renal aging through PGE2/EP1‐dependent senescence and disrupts renal endocrine support for bone homeostasis. Genetic deletion or pharmacological inhibition of mPGES‐2 protects aged mice from kidney dysfunction and osteoporosis. ABSTRACT Renal aging shortens healthspan and propagates organ dysfunction beyond the kidney, yet its ...
Dandan Zhong +16 more
wiley +1 more source
Effects of chronic sleep deprivation on the bone mineral density, bone microarchitecture and body weight of mice: exploratory study. [PDF]
Xiang W +10 more
europepmc +1 more source
This study investigated the bidirectional relationship and shared mechanisms between sarcopenia and osteoporosis using data from the UK Biobank. Our findings indicated that the two conditions may act as reciprocal risk factors, with multiple potential biomarkers mediating the muscle‐bone relationship and suggested possible shared signals between the ...
Siqi Xu +10 more
wiley +1 more source
Role of bone microarchitecture and hereditary determinants of bone fragility
Le rôle de la microstructure trabéculaire et corticale dans la résistance osseuse et le risque de fracture est bien documenté mais son déterminisme génétique n’a pas encore été étudié.
Abdelmohsen Ali Mohamed Nagy, Hoda
core
Evaluation of TMJ bone microarchitecture in malocclusion and tooth loss using fractal dimension analysis. [PDF]
Balel Y.
europepmc +1 more source
ABSTRACT Aims To evaluate the associations between semaglutide initiation and long‐term skeletal outcomes in people with obesity, stratified by type 2 diabetes (T2D) status, using target trial emulation. Materials and Methods This retrospective cohort study used the TriNetX federated electronic health record network.
Yu‐Nan Huang +8 more
wiley +1 more source
Close to the bone: investigations into bone tissue mineralisation and mechanobiology of osteoporosis
Osteoporosis is a metabolic skeletal disease characterized by low bone mass, depleted micro-architecture and reduced strength. The public health costs of osteoporosis relate almost entirely to the fractures that are the clinical manifestation of the ...
Brennan, Meadhbh
core

