Results 91 to 100 of about 2,935,673 (409)

Bone Quality and Fractures in Women With Osteoporosis Treated With Bisphosphonates for 1 to 14 Years

open access: yesJBMR Plus, 2021
Oral bisphosphonates are the primary medication for osteoporosis, but concerns exist regarding potential bone‐quality changes or low‐energy fractures.
Hartmut H Malluche   +5 more
doaj   +1 more source

Novel Immune Cell Subsets Exhibit Different Associations With Vascular Outcomes in Chronic Kidney Disease Patients—Identifying Potential Biomarkers

open access: yesFrontiers in Medicine, 2021
Background and Aims: Alterations in novel immune cell subsets, such as angiogenic T cells (Tang), senescent T cells (CD4+CD28null), and monocyte subsets are associated with impaired vascular homeostasis in several inflammatory conditions.
Javier Rodríguez-Carrio   +30 more
doaj   +1 more source

Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis [PDF]

open access: yes, 2006
BACKGROUND: Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. METHODS: We performed a randomized, double-placebo, double-blind clinical trial of 18 months' duration ...
Ale Algra   +14 more
core   +4 more sources

Modelling Atherosclerotic Plaque Cap Mechanics: Microcalcifications Reduce Mechanical Properties in Mesenchymal Stromal Cell‐Based Model

open access: yesAdvanced Biology, EarlyView.
This study develops a tissue‐engineered model of the atherosclerotic cap using human mesenchymal stromal cells (MSCs). After 2 weeks of culture to produce a collagenous matrix, a mineralizing medium induces microcalcifications over 4 weeks. These constructs, imaged with second harmonic generation microscopy, lead to reduced ultimate stress at rupture ...
Imke L. Jansen   +4 more
wiley   +1 more source

X‐Linked Hypophosphatemia Caused by the Prevailing North American PHEX Variant c.*231A>G; Exon 13–15 Duplication Is Often Misdiagnosed as Ankylosing Spondylitis and Manifests in Both Men and Women

open access: yesJBMR Plus, 2022
Inactivating mutations of the gene coding for phosphate‐regulating endopeptidase homolog X‐linked (PHEX) cause X‐linked hypophosphatemia (XLH). A novel PHEX variant, c.*231A>G; exon 13–15 duplication, has emerged as a common cause of XLH in North America,
Kathryn McCrystal Dahir   +6 more
doaj   +1 more source

Multiple verification in computational modeling of bone pathologies

open access: yes, 2011
We introduce a model checking approach to diagnose the emerging of bone pathologies. The implementation of a new model of bone remodeling in PRISM has led to an interesting characterization of osteoporosis as a defective bone remodeling dynamics with ...
A. Aziz   +21 more
core   +2 more sources

Bridging Nature and Technology: A Perspective on Role of Machine Learning in Bioinspired Ceramics

open access: yesAdvanced Engineering Materials, EarlyView.
Machine learning (ML) is revolutionizing the development of bioinspired ceramics. This article investigates how ML can be used to design new ceramic materials with exceptional performance, inspired by the structures found in nature. The research highlights how ML can predict material properties, optimize designs, and create advanced models to unlock a ...
Hamidreza Yazdani Sarvestani   +2 more
wiley   +1 more source

From Nature to Engineering: Mortar Volume and Interfacial Mechanics in Bioinspired Ceramics

open access: yesAdvanced Engineering Materials, EarlyView.
Inspired by natural armors like nacre, this study explores how varying the volume fraction of the soft mortar layer impacts the interfacial strength and toughness of bioinspired ceramics. Experimental and computational analysis reveals that higher mortar volumes increase energy dissipation but reduce interfacial stiffness, offering insights for ...
Ehsan Azad   +4 more
wiley   +1 more source

N-cadherin in osteolineage cells modulates stromal support of tumor growth

open access: yesJournal of Bone Oncology, 2021
Tumor growth and metastases are dependent on interactions between cancer cells and the local environment. Expression of the cell–cell adhesion molecule N-cadherin (Ncad) is associated with highly aggressive cancers, and its expression by osteogenic cells
Francesca Fontana   +8 more
doaj  

PENGGUNAAN BONE GRAFT PADA PERAWATAN KERUSAKAN TULANG PERIODONTAL (Used Bone Graft for Periodontal Defect Treatment)

open access: yesJournal of Dentistry Indonesia, 2015
Generally the signs and symptoms of advances periodontal disease are periodontal pockets formation to alveolar bone defect. Bone defect treated with placement a preparation material to promote new bone formation. Tissue transplantation were developed, to
Elly Munadziroh   +2 more
doaj   +1 more source

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