Results 91 to 100 of about 2,979,968 (410)

Development and Preliminary In Vivo Study of 3D‐Printed Bioactive Glass Scaffolds with Trabecular Architecture

Advanced Engineering Materials, EarlyView.
This study reports the fabrication of trabecular bioactive glass scaffolds (composition “1d”: 46.1SiO2‐28.7CaO‐8.8MgO‐6.2P2O5‐5.7CaF2‐4.5Na2O wt%) through vat photopolymerization and the relevant results from mechanical testing and in vivo implantation procedures in rabbit femora, showing great promise for bone tissue engineering applications.
Dilshat Tulyaganov, Roberta Gabrieli, Avzal Akbarov, Nigora Nigmatova, Bekhzod Khabilov, Alessandro Schiavi, Martin Schwentenwein, Enrica Verné, Francesco Baino   +8 more
wiley   +1 more source

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

Advanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo, Chiara Arrigoni, Tobias Faehling, Antonietta Verrillo, Viviana Secci, Thomas G. P. Grünewald, Giuseppe Talò, Alexandra Kummer, Jorge Gonzalez, Vincenzo De Rosa, Christian Candrian, Andrea Barbero, Florencia Cidre‐Aranaz, Matteo Moretti   +13 more
wiley   +1 more source

Increased autophagy in EphrinB2-deficient osteocytes is associated with elevated secondary mineralization and brittle bone [PDF]

, 2019
Mineralized bone forms when collagen-containing osteoid accrues mineral crystals. This is initiated rapidly (primary mineralization), and continues slowly (secondary mineralization) until bone is remodeled. The interconnected osteocyte network within the
Vrahnas, Christina, Blank, Martha, Dite, Toby A, Tatarczuch, Liliana, Ansari, Niloufar, Crimeen-Irwin, Blessing, Nguyen, Huynh, Forwood, Mark R, Hu, Yifang, Ikegame, Mika, Bambery, Keith R, Petibois, Cyril, Mackie, Eleanor J, Tobin, Mark J, Smyth, Gordon K, Oakhill, Jonathan S, Martin, T John, Sims, Natalie A   +17 more
core   +1 more source

An Investigation of the Mineral in Ductile and Brittle Cortical Mouse Bone

Journal of Bone and Mineral Research, 2015
Bone is a strong and tough material composed of apatite mineral, organic matter, and water. Changes in composition and organization of these building blocks affect bone's mechanical integrity.
N. Rodríguez-Flórez, Esther García-Tuñón, Quresh Mukadam, E. Saiz, Karla J. Oldknow, C. Farquharson, J. Millán, A. Boyde, S. Shefelbine   +8 more
semanticscholar   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Measurement of bone quality in growing male rats using dual energy x-ray absorptiometry and bone ash content : a thesis presented in partial fulfilment of the requirements for the degree of Master of Applied Science in Animal Science at Massey University, Palmerston North, New Zealand [PDF]

, 2001
Growing male rats have been considered and used as a model for bone growth and prevention of osteoporosis because of their high bone turnover and demand for calcium. Dual Energy X-ray Absorptiometry (DEXA) is a useful tool for identifying minimal changes
Brown, Katherine Elizabeth
core  

Shared Autonomic Pathways Connect Bone Marrow and Peripheral Adipose Tissues Across the Central Neuraxis

Frontiers in Endocrinology, 2019
Bone marrow adipose tissue (BMAT) is increased in both obesity and anorexia. This is unique relative to white adipose tissue (WAT), which is generally more attuned to metabolic demand.
Natalie K. Y. Wee, Natalie K. Y. Wee, Madelyn R. Lorenz, Yusuf Bekirov, Mark F. Jacquin, Erica L. Scheller, Erica L. Scheller   +6 more
doaj   +1 more source

Bioactive calcium phosphate materials and applications in bone regeneration

Biomaterials Research, 2019
BackgroundBone regeneration involves various complex biological processes. Many experiments have been performed using biomaterials in vivo and in vitro to promote and understand bone regeneration.
Jiwoong Jeong, J. H. Kim, J. Shim, Nathaniel S. Hwang, C. Heo   +4 more
semanticscholar   +1 more source

Bone Mineral Density and Stroke [PDF]

Stroke, 2003
Background and Purpose— We sought to assess the long-term predictive usefulness of bone mineral density (BMD) for stroke incidence and stroke mortality. Methods— The First National Health and Nutrition Examination Survey data ...
Michael E. Mussolino, Richard F. Gillum, Jennifer H. Madans   +2 more
openaire   +3 more sources

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

Advanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee, Ruqiang Lu, Andrew House, Zizhao Li, Lindsey Hammond Burton, Katie Josephine Sikes, Lynn Marie Pezzanite, Drew William Koch, Kevin Michael Labus, Ben Gadomski, Jeremiah Easley, Richard Tuan Tran, Su Chin Heo   +12 more
wiley   +1 more source