Results 121 to 130 of about 2,935,673 (409)

Anionic Citrate‐Based 3D‐Printed Scaffolds for Tunable and Sustained Orthobiologic Delivery to Enhance Tissue Regeneration

Advanced Functional Materials, EarlyView.
A potent anionic citric acid‐based 3D‐printed scaffold is developed for the sustained and controlled release of orthobiologics to enhance orthopedic therapeutic efficacy. Comprehensive in vivo studies demonstrated effective bone fusion and high safety at a low dose of BMP‐2 delivered by the system, establishing it as a promising platform for safe ...
Se‐Hwan Lee, Ruqiang Lu, Andrew House, Zizhao Li, Lindsey Hammond Burton, Katie Josephine Sikes, Lynn Marie Pezzanite, Drew William Koch, Kevin Michael Labus, Ben Gadomski, Jeremiah Easley, Richard Tuan Tran, Su Chin Heo   +12 more
wiley   +1 more source

Development of an injectable composite for bone regeneration [PDF]

, 2013
With the development of minimally invasive surgical techniques, there is a growing interest in the research and development of injectable biomaterials especially for orthopedic applications.
Amédée, Joelle, Anagnostou, Fani, Auzély-Velty, Rachel, Bareille, Reine, Belime, Agathe, Bignon, Aurélien, Brouillet, Fabien, Combes, Christèle, Cordier, Delphine, El Kissi, Nadia, Fatnassi, Mohamed, Galliard, Hélène, Girod-Fullana, Sophie, Hénocq-Pigasse, Christel, Jacquart, Sylvaine, Rey, Christian, Roques, Christine, Siadous, Robin, Tadier, Solène   +18 more
core   +5 more sources

Dual‐Nanoparticle Engineered Hydrogel Reverses Bicellular Oxidative Stress to Accelerate Diabetic Fracture Healing

Advanced Functional Materials, EarlyView.
CD105‐LNPs and PS‐LNPs can deliver α‐lipoic acid to bone marrow mesenchymal stem cells and bone marrow‐derived macrophages, reversing high glucose‐induced oxidative stress while enhancing osteogenesis and M2 polarization. Integrating both nanoparticles into glucose‐responsive hyaluronic acid hydrogel forms DLNPs@HA hydrogel, which accelerates diabetic ...
Yanzhi Zhao, Weixian Hu, Shengming Zhang, Yuheng Liao, Kangkang Zha, Chenyan Yu, Zhenhe Zhang, Wenqian Zhang, Bobin Mi, Faqi Cao, Guohui Liu, Wu Zhou   +11 more
wiley   +1 more source

Positioning novel biologicals in CKD-mineral and bone disorders [PDF]

, 2017
Renal osteodystrophy (ROD), the histologic bone lesions of chronic kidney disease (CKD), is now included in a wider syndrome with laboratory abnormalities of mineral metabolism and extra-skeletal calcifications or CKD-mineral and bone disorders (CKD-MBD),
Covic, Adrian, Mazzaferro, Sandro, Muci, MARIA LUISA, Pasquali, Marzia, Rotondi, Silverio, Tartaglione, Lida   +5 more
core   +1 more source

3D Concrete Printing of Triply Periodic Minimum Surfaces for Enhanced Carbon Capture and Storage

Advanced Functional Materials, EarlyView.
A 3D‐printable and carbon‐capturing concrete is developed by replacing cement with diatomaceous earth (DE), which enhances rheology, provides hierarchical porosity, and serves as a nucleation site for carbonation. Maximum absorption of 488.7 gCO2 kgcement−1 is achieved in 7 days, a 142% increase over conventional concrete, and the triply periodic ...
Kun‐Hao Yu, Teng Teng, So Hee Nah, Hua Chai, Yefan Zhi, Kun‐Yu Wang, Yinding Chi, Peter Psarras, Masoud Akbarzadeh, Shu Yang   +9 more
wiley   +1 more source

Graded Hydroxyapatite Triply Periodic Minimal Surface Structures for Bone Tissue Engineering Applications

Advanced Healthcare Materials, EarlyView.
This study investigates the role of triply periodic minimal structures in load bearing bone tissue engineering applications. Research uses a combination of mechanical testing, material characterization, and in vitro tests to study the impact of TPMS lattice structures (gyroid, lidinoid and split‐P).
Tejas M. Koushik, Catherine M. Miller, Elsa Antunes   +2 more
wiley   +1 more source

Inhibition of Acid Phosphatase Enzyme Activity in the Presence of Noncrystalline Calcium Phosphate and Nanocrystalline Calcium Apatite: a Preliminary Study [PDF]

, 2009
*Background* Our bones are remodelled repeatedly during life. A new and “healthy” bone tissue replaces the old one. Accordingly, the bone degrading cells, the osteoclasts, prefer old and fatigued bone.
Yassen Pekounov
core   +2 more sources

Bone mineral density in Iranian patients: Effects of age, sex, and body mass index [PDF]

, 2013
Introduction: Osteoporosis is a multifactorial skeletal disease that is characterized by reduced bone mineral density (BMD). BMD values de-pend on several factors such as age, sex and age at menopause.
Aghaei, M., Bazrafshan, H.R., Qorbani, M., Safari, R., Shadpour Dashti, H.   +4 more
core   +1 more source

Longer Acting Injectable: Continuous, Linear Release of a Progestin Contraceptive From an Oxidized Porous Silicon Host

Advanced Healthcare Materials, EarlyView.
Progestin drugs are loaded into a mesoporous silicon dioxide host by melt‐infiltration. Drugs that decompose at or close to their melting point can be loaded by the addition of cholesterol, which acts as a melting point suppressor. High mass loading of the drug is achieved, and dissolution of the composite is controlled by the nanoscale properties of ...
Geoffrey Hollett, Ruhan Fan, Tushar Kumeria, Heidi Leonard, Byungji Kim, Taylor R. Martin, Irmak Ipekci, Joanna Wang, Jiuk Byun, Nicole A. Chan, Amber Pierron, Curtis E. Moore, Jennifer Ayres, Michael J. Sailor   +13 more
wiley   +1 more source

A postmenopausal osteoporotic woman losing bone mineral density despite bisphosphonates [PDF]

Malaysian Family Physician, 2013
Bisphosphonates are pyrophosphate analogues, with a strong affinity for bones. They inhibit bone resorption and are currently the first choice of treatment for osteoporosis.
Lai PSM, Nagammai T, Vethakkan SR
doaj