Results 161 to 170 of about 226,513 (310)

Treatment with Minicircle DNA Expressing a FGF23 Fragment in a Clinically relevant Mouse Model of X‐Linked Hypophosphatemic Rickets

Advanced Science, EarlyView.
The pathogenic role of PHEX isn't fully determined, and there is no radical cure for X‐linked hypophosphatemic rickets (XLHR). This study makes the first attempt to perform gene therapy using a minicircle DNA (MC‐DNA) vector expressing a fragment of FGF23 (amino acids 180‐251) in Phex‐T1349C mice and suggests MC‐DNA as a promisingly safe and effective ...
Huixiao Wu, Wanyi Zhao, Xinyu Chen, Yanzhou Wang, Shuoshuo Wei, Bo Xiang, Yingzhou Shi, Zongyue Li, Yangyang Yao, Jin Xie, Renyuan Qiu, Meng Shu, Shuo Xu, Ping Chen, Zhiying Chen, Yingjie Wu, Weibo Xia, Ling Gao, Yongfeng Song, Jiajun Zhao, Chao Xu   +20 more
wiley   +1 more source

The Effect of Proton Pump Inhibitors on Bone Mineral Density at Specific Anatomical Sites: A Systematic Review and Meta-Analysis. [PDF]

Biomed Res Int
Ali AA, Bhongade BA, Alkaabi FM.
europepmc   +1 more source

Bifurcate Regulation of Hematopoietic Homeostasis and Bone Osteogenesis by VHL‐HIF2α‐Controlled Adipocyte Function

Advanced Science, EarlyView.
The VHL‐HIF2α (VHL is Von Hippel‐Lindau) axis in adipocytes differentially regulates hematopoiesis and bone formation through stem cell factor (SCF) and chemerin, respectively. This hypoxia‐responsive pathway in adipocytes establishes a systemic signaling network with HSCs and MSCs to maintain tissue homeostasis, revealing a targetable axis for ...
Qian Li, Jia Li, Anshu Tang, Cong Li, Chao Zhang, Congcong Zhang, Yun‐Cai Liu   +6 more
wiley   +1 more source

#48. N-cadherin in tumor-associated Osx+ cells is anti-tumorigenic

Journal of Bone Oncology
Toshi Sugatani, Roberto Civitelli
doaj   +1 more source

Genetic Insights Into the Relationship Between Menstrual Factors and Site-/Age-Specific Bone Mineral Density. [PDF]

Int J Genomics
Li S, Zhu YY, Hu X, Shi QQ, Deng JJ, Wei HF, Ma CR, Pan HF, Wang P.   +8 more
europepmc   +1 more source

Mapping the Tissue‐of‐Origins of Mesenchymal Stromal Cells in Injury Repair

Advanced Science, EarlyView.
This study maps mesenchymal stromal cells (MSCs) across multiple tissues, revealing that bone marrow–derived MSCs mobilize monocytes via CCL2 to promote systemic inflammation but do not migrate to distant organs to form fibrotic or tumor stroma. Instead, local MSCs dominate tissue remodeling, suggesting a “two‐hit” model linking systemic inflammation ...
Xinyu Thomas Tang, Yiming Liam Liu, Yidi Augenstern Du, Shan−Shan Wang, Bo O. Zhou   +4 more
wiley   +1 more source

Serum zinc is positively associated with bone mineral density: A cross-sectional analysis of NHANES 2011-2016. [PDF]

Medicine (Baltimore)
Wu Z, Liu C, Huang Z, Lan Z, Lin X, Chen L, Lin J, Xu Z.   +7 more
europepmc   +1 more source

The Association between Serum Copper and Bone Mineral Density among Adolescents Aged 12 to 19 in the United States [PDF]

Haobiao Liu, Miaoye Bao, Mian Liu, Feidan Deng, Xinyue Wen, Ping Wan, Xue Lin, Guoqiang Dong, Zhaoyang Li, Jing Han   +9 more
openalex   +1 more source

Burn‐Safe Biodegradable Magnetocaloric Composites for Temperature‐Controlled Biomedical Applications

Advanced Science, EarlyView.
This work investigates a magnetocaloric (Mn,Fe)2(P,Si) compound tailored for precise, self‐regulating heating in biomedical use. With a Curie temperature tuned at 43 °C, it enables therapeutic activation without overheating. Encapsulation in a composite ensures controlled temperature rise under an alternating magnetic field (AMF), with high ...
Pornpawee Uliss, Wuliji Hanggai, Friso Kahler, Elena Aprea, Qi Jia, Vasiliki Gkouzioti, Jean‐Philippe Frimat, Ekkes Brück, Clementine M. Boutry   +8 more
wiley   +1 more source

Bone Mineral Density in HIV-Infected People-the Experience of Craiova Regional Center. [PDF]

Biomedicines
Dumitrescu F, Dragonu L, Marcu EA, Pădureanu V, Stoian AC, Rădoi-Troacă CL, Pădureanu R, Duduveche A, Georgescu IA, Giubelan L.   +9 more
europepmc   +1 more source