Results 21 to 30 of about 226,513 (310)

Rickets manifestations in a child with metaphyseal anadysplasia, report of a spontaneously resolving case

open access: yesBMC Pediatrics, 2021
Introduction Rickets is not an unusual diagnosis for pediatricians even currently in developed countries. Children typically present with leg bowing, enlargement of wrists, rachitic rosary (swelling of costochondral junctions) and/or waddling gait.
Patricia Diaz Escagedo   +7 more
doaj   +1 more source

Large parathyroid adenomas: Potential mechanisms to reconcile adenoma size and disease phenotype

open access: yesFrontiers in Endocrinology, 2023
Parathyroid adenomas weighing more than 3.5 g are reported variously as “atypical”, “large” or “giant” parathyroid adenomas. All such adenomas are rare variants accounting for no more than 1.5% of all parathyroid adenomas.
Arti Bhan   +8 more
doaj   +1 more source

Bone mineral crystallisation kinetics [PDF]

open access: yesJournal of Materials Science: Materials in Medicine, 2012
The kinetics of bone apatite crystallisation are examined using a novel approach to obtain quantitative, direction dependence features such as growth rate and activation energy. X-ray diffraction was employed for analysis of bovine, porcine and 'anorganic' bone specimens.
Greenwood, C   +3 more
openaire   +3 more sources

N-cadherin in osteolineage cells modulates stromal support of tumor growth

open access: yesJournal of Bone Oncology, 2021
Tumor growth and metastases are dependent on interactions between cancer cells and the local environment. Expression of the cell–cell adhesion molecule N-cadherin (Ncad) is associated with highly aggressive cancers, and its expression by osteogenic cells
Francesca Fontana   +8 more
doaj   +1 more source

Lack of PTEN in osteocytes increases circulating phosphate concentrations by decreasing intact fibroblast growth factor 23 levels

open access: yesScientific Reports, 2020
Fibroblast growth factor 23 (FGF23) has been centric to the regulation of phosphate (Pi) metabolism; however, the regulatory network of FGF23 in osteocytes has not yet been defined in detail.
Masanobu Kawai   +3 more
doaj   +1 more source

Multitasking by the OC Lineage during Bone Infection: Bone Resorption, Immune Modulation, and Microbial Niche

open access: yesCells, 2020
Bone infections, also known as infectious osteomyelitis, are accompanied by significant inflammation, osteolysis, and necrosis. Osteoclasts (OCs) are the bone-resorbing cells that work in concert with osteoblasts and osteocytes to properly maintain ...
Philip M. Roper   +2 more
doaj   +1 more source

Bone Nanomechanical Properties and Relationship to Bone Turnover and Architecture in Patients With Atypical Femur Fractures: A Prospective Nested Case‐Control Study

open access: yesJBMR Plus, 2021
Atypical femur fractures (AFFs) are well‐established serious complication of long‐term bisphosphonate and denosumab therapy in patients with osteopenia or osteoporosis.
Lanny V. Griffin   +7 more
doaj   +1 more source

Bone matrix components activate the NLRP3 inflammasome and promote osteoclast differentiation

open access: yesScientific Reports, 2017
The NLRP3 inflammasome senses a variety of signals referred to as danger associated molecular patterns (DAMPs), including those triggered by crystalline particulates or degradation products of extracellular matrix. Since some DAMPs confer tissue-specific
Yael Alippe   +9 more
doaj   +1 more source

The Impact of Whole-Body Vibration Training on Bone Minerals and Lean Mass in Children and Adolescents with Motor Disabilities: A Systematic Review and Meta-Analysis

open access: yesChildren, 2022
Whole-body vibration training (WBVT) offers a potential auxiliary treatment method for the rehabilitation of motor disabilities to address a reduction in bone minerals and lean mass caused by motor-disability rehabilitation. The aim of this review was to
Shuoqi Li   +5 more
doaj   +1 more source

Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells

open access: yesScientific Reports, 2017
Skeletal complications are common features of neonatal-onset multisystem inflammatory disease (NOMID), a disorder caused by NLRP3-activating mutations. NOMID mice in which NLRP3 is activated globally exhibit several characteristics of the human disease ...
Chun Wang   +8 more
doaj   +1 more source

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