Results 21 to 30 of about 259,849 (237)

Bone mineral density and fracture risk with long-term use of inhaled corticosteroids in patients with asthma: systematic review and meta-analysis [PDF]

open access: yes, 2015
Objectives: We aimed to assess the association between long-term use of inhaled corticosteroids (ICS) and bone adverse effects in patients with asthma. Design: Systematic review and meta-analysis of fracture risk and changes in bone mineral density with ...
Agertoft   +32 more
core   +1 more source

Bone matrix components activate the NLRP3 inflammasome and promote osteoclast differentiation

open access: yesScientific Reports, 2017
The NLRP3 inflammasome senses a variety of signals referred to as danger associated molecular patterns (DAMPs), including those triggered by crystalline particulates or degradation products of extracellular matrix. Since some DAMPs confer tissue-specific
Yael Alippe   +9 more
doaj   +1 more source

Chronic inflammation triggered by the NLRP3 inflammasome in myeloid cells promotes growth plate dysplasia by mesenchymal cells

open access: yesScientific Reports, 2017
Skeletal complications are common features of neonatal-onset multisystem inflammatory disease (NOMID), a disorder caused by NLRP3-activating mutations. NOMID mice in which NLRP3 is activated globally exhibit several characteristics of the human disease ...
Chun Wang   +8 more
doaj   +1 more source

Investigation of the cellular response to bone fractures: evidence for flexoelectricity [PDF]

open access: yesScientific Reports volume 10, Article number: 254 (2020), 2020
The recent discovery of bone flexoelectricity (electrical polarization induced by strain gradient) suggests that flexoelectricity could have physiological effects in bones, and specifically near bone fractures, where flexoelectricity is theoretically highest. Here, we report a cytological study of the interaction between crack stress and bone cells. We
arxiv   +1 more source

Bone mineral metabolism status, quality of life, and muscle strength in older people [PDF]

open access: yes, 2019
Producción CientíficaAs the relationship between vitamin D and various diseases or health conditions has become known, interest in the contribution of vitamin D to overall health-related quality of life (QoL) has increased.
Díaz Ondina, Marta   +4 more
core   +1 more source

The Impact of Whole-Body Vibration Training on Bone Minerals and Lean Mass in Children and Adolescents with Motor Disabilities: A Systematic Review and Meta-Analysis

open access: yesChildren, 2022
Whole-body vibration training (WBVT) offers a potential auxiliary treatment method for the rehabilitation of motor disabilities to address a reduction in bone minerals and lean mass caused by motor-disability rehabilitation. The aim of this review was to
Shuoqi Li   +5 more
doaj   +1 more source

A retrospective analysis of longitudinal changes in bone mineral content in cystic fibrosis [PDF]

open access: yes, 2017
Background: We aimed to describe the longitudinal changes in bone mineral content and influencing factors, in children with cystic fibrosis (CF). Methods: One hundred children (50 females) had dual X-ray absorptiometry (DXA) performed.
Ahmed, Syed Faisal   +7 more
core   +1 more source

Mechanics of mineralized collagen fibrils upon transient loads [PDF]

open access: yesACS Nano, 2020, 2020
Collagen is a key structural protein in the human body, which undergoes mineralization during the formation of hard tissues. Earlier studies have described the mechanical behavior of bone at different scales highlighting material features across hierarchical structures.
arxiv   +1 more source

Gasdermin D deficiency attenuates arthritis induced by traumatic injury but not autoantibody-assembled immune complexes

open access: yesArthritis Research & Therapy, 2021
Background Gasdermin D (GSDMD) is cleaved by several proteases including by caspase-1, a component of intracellular protein complexes called inflammasomes.
Tong Yang   +14 more
doaj   +1 more source

Thyroid hormone status within the physiological range affects bone mass and density in healthy men at the age of peak bone mass [PDF]

open access: yes, 2011
Context: The hormonal factors involved in the regulation of peak bone mass (PBM) in men have not been fully investigated. Apart from gonadal steroids and somatotropic hormones, thyroid hormones are known to affect bone maturation and homeostasis and are ...
Fiers, Tom   +6 more
core   +2 more sources

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