Results 301 to 310 of about 2,979,968 (410)

Odanacatib in the treatment of postmenopausal women with low bone mineral density: Five years of continued therapy in a phase 2 study

open access: yesJournal of Bone and Mineral Research, 2012
B. Langdahl   +11 more
semanticscholar   +1 more source

The Pathogenic Roles of Local Vitamin D Metabolism Defect in Valve Inflammation and Calcification

open access: yesAdvanced Science, EarlyView.
This study identifies the valvular interstitial cell populations responsible for valvular calcification induced by hyperphosphatemia and likely aging, uncovers local vitamin D metabolism defect‐induced inflammation as a critical pathogenic factor of calcific aortic valve disease, and highlights active vitamin D and ERK inhibitor as potential preventive
Ruichen Yang   +10 more
wiley   +1 more source

[Correlation between bone mineral density and bone metabolic markers in preschool children and the influencing factors for bone mineral density]. [PDF]

open access: yesZhongguo Dang Dai Er Ke Za Zhi
Ni L   +7 more
europepmc   +1 more source

Effects of denosumab treatment and discontinuation on bone mineral density and bone turnover markers in postmenopausal women with low bone mass.

open access: yesJournal of Clinical Endocrinology and Metabolism, 2011
H. Bone   +8 more
semanticscholar   +1 more source

PIEZO1‐GPX4 Axis Mediates Mechanical Stress‐Induced Vertebral Growth Plate Dysplasia via Ferroptosis Activation

open access: yesAdvanced Science, EarlyView.
Mechanical stress activates PIEZO1 in vertebral growth plate chondrocytes, triggering ferroptosis through direct binding and inhibition of GPX4. This axis promotes lipid peroxidation and pathological ossification, accelerating spinal deformities. Clinical and genetic evidence (Piezo1‐cKO) confirms its role in scoliosis progression.
Fei Chen   +14 more
wiley   +1 more source

Relationship of age to bone microstructure independent of areal bone mineral density

open access: yesJournal of Bone and Mineral Research, 2012
K. M. Nicks   +5 more
semanticscholar   +1 more source

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