The mechanism diagram reveals that the formation of trauma‐induced heterotopic ossification (HO) is accompanied by the polarization of macrophages toward the M1 phenotype. Additionally, the extracellular vesicles secreted by M1 macrophages, which contain periostin (POSTN), directly bind to PTK7 in tendon‐derived stem cells (TDSCs).
Hang Liu+9 more
wiley +1 more source
Effect of Tai Chi on Bone Mineral Density in Middle-Aged and Older Adults: A Meta-Analysis. [PDF]
Cui J, Qian C, Liu Y.
europepmc +1 more source
This study establishes a bio‐electroceutical interface by synergizing engineered exosome‐derived biological signals with electroconductive microneedle‐delivered electrical cues, achieving dual‐pathway reprogramming of the diabetic neurovascular niches and accelerating wound healing. Abstract Diabetic wound healing remains a major clinical challenge due
Di Liu+5 more
wiley +1 more source
Long-Term Oral Budesonide Use in Inflammatory Bowel Disease: Effects on Bone Mineral Density and Late-Onset Adverse Events. [PDF]
Eskazan T+8 more
europepmc +1 more source
Microphysiological Solid Tumor Models in Hydrogel Beads for CAR T Cell Immunotherapy Evaluation
The complex physical and biochemical barriers of the tumor microenvironment are major triggers of immune exclusion. Here, a 3D micrometastasis model is developed to mimic key microenvironmental cues, enabling in vitro evaluation of chimeric antigen receptor (CAR) T cell immunotherapy. Abstract Micrometastases are challenging to resect surgically and to
Xuan Peng+14 more
wiley +1 more source
Bone Mineral Density in Children with Cerebral Palsy: Associations with Anthropometric and Clinical Characteristics-A Cross-Sectional Study. [PDF]
Aljishi AA+4 more
europepmc +1 more source
Additive manufacturing enables complex structures, but polymer printing often suffers from poor interlayer fusion and defects induced by heat or binders. A two‐step, room‐temperature strategy based on immersion phase separation (IPS‐E3DP) achieves precise liquid‐state fusion with high structural fidelity, enhanced mechanical performance, broad material
Kaidong Song+11 more
wiley +1 more source
Bone Mineral Density and Serum Levels of Bone Remodeling Markers in Ankylosing Spondylitis Treated with Anti TNF-α Agents. [PDF]
Alvarez-Ayala EG+15 more
europepmc +1 more source
Identification and Validation of Novel Lipids Linked to Bone Mineral Density Change and Fracture Risk. [PDF]
Ma C+8 more
europepmc +1 more source
Association of skeletal muscle strength and cardiorespiratory fitness with bone mineral density: a cross-sectional study. [PDF]
Wei B+9 more
europepmc +1 more source