Results 41 to 50 of about 2,979,968 (410)
Micro-CT Characterization of Human Trabecular Bone in Osteogenesis Imperfecta [PDF]
, 2011 Osteogenesis imperfecta (OI) is a genetic syndrome affecting collagen synthesis and assembly. Its symptoms vary widely but commonly include bone fragility, reduced stature, and bone deformity.
Albert, Carolyne +4 more
core +2 more sources
Bone and Mineral Metabolism [PDF]
Emergency Medicine Clinics of North America, 2005 Although bones are normally thought of as supporting structures that fracture when one falls, bone is actually a very active metabolic organ. It is vital in the regulation of calcium and phosphate metabolism, magnesium storage, and in buffering metabolic acido-sis. Bone and mineral metabolism and some of their disorders are presented in this article.
openaire +5 more sources
Arthritis Research & Therapy, 2021 Background Gasdermin D (GSDMD) is cleaved by several proteases including by caspase-1, a component of intracellular protein complexes called inflammasomes.
Tong Yang +14 more
doaj +1 more source
Immunoporosis: Role of immune system in the pathophysiology of different types of osteoporosis
Frontiers in Endocrinology, 2022 Osteoporosis is a skeletal system disease characterized by low bone mass and altered bone microarchitecture, with an increased risk of fractures. Classical theories hold that osteoporosis is essentially a bone remodeling disorder caused by estrogen ...
Weidong Zhang +13 more
doaj +1 more source
Vitamin D and Serum Cytokines in a Randomized Clinical Trial
International Journal of Endocrinology, 2010 Background. The role of vitamin D in the body's ability to fight influenza and URI's may be dependent on regulation of specific cytokines that participate in the host inflammatory response.
Eleanor Yusupov +5 more
doaj +1 more source
Journal of Bone and Mineral Research, 2015 Sclerostin, a SOST protein secreted by osteocytes, negatively regulates formation of mineralized bone matrix and bone mass. We report the results of a randomized, double‐blind, placebo‐controlled multicenter phase 2 clinical trial of blosozumab, a ...
R. Recker +11 more
semanticscholar +1 more source
Bone Mineralization in Celiac Disease [PDF]
Gastroenterology Research and Practice, 2012 Evidence indicates a well-established relationship between low bone mineral density (BMD) and celiac disease (CD), but data on the pathogenesis of bone derangement in this setting are still inconclusive. In patients with symptomatic CD, low BMD appears to be directly related to the intestinal malabsorption.
Francesco Luzza +5 more
openaire +4 more sources
Alendronate or alfacalcidol in glucocorticoid-induced osteoporosis [PDF]
, 2006 BACKGROUND: Treatment with glucocorticoids is associated with bone loss starting soon after therapy is initiated and an increased risk of fracture. METHODS: We performed a randomized, double-placebo, double-blind clinical trial of 18 months' duration ...
Ale Algra +14 more
core +4 more sources
Calcium Intake in Bone Health: A Focus on Calcium-Rich Mineral Waters
Nutrients, 2018 Calcium is an essential element that plays numerous biological functions in the human body, of which one of the most important is skeleton mineralization. Bone is a mineralized connective tissue in which calcium represents the major component, conferring
Letizia Vannucci +10 more
semanticscholar +1 more source
Mineralization of Hydrogels for Bone Regeneration [PDF]
Tissue Engineering Part B: Reviews, 2010 Hydrogels are an important class of highly hydrated polymers that are widely investigated for potential use in soft tissue engineering. Generally, however, hydrogels lack the ability to mineralize, preventing the formation of chemical bonds with hard tissues such as bone.
Gkioni, K. +4 more
openaire +4 more sources