Results 101 to 110 of about 505,690 (397)

Longer Acting Injectable: Continuous, Linear Release of a Progestin Contraceptive From an Oxidized Porous Silicon Host

Advanced Healthcare Materials, EarlyView.
Progestin drugs are loaded into a mesoporous silicon dioxide host by melt‐infiltration. Drugs that decompose at or close to their melting point can be loaded by the addition of cholesterol, which acts as a melting point suppressor. High mass loading of the drug is achieved, and dissolution of the composite is controlled by the nanoscale properties of ...
Geoffrey Hollett, Ruhan Fan, Tushar Kumeria, Heidi Leonard, Byungji Kim, Taylor R. Martin, Irmak Ipekci, Joanna Wang, Jiuk Byun, Nicole A. Chan, Amber Pierron, Curtis E. Moore, Jennifer Ayres, Michael J. Sailor   +13 more
wiley   +1 more source

Mechanical response tissue analyzer for estimating bone strength [PDF]

One of the major concerns for extended space flight is weakness of the long bones of the legs, composed primarily of cortical bone, that functions to provide mechanical support.
Arnaud, Sara B., Mauriello, Anthony, Steele, Charles   +2 more
core   +1 more source

Dexamethasone Delivery via Amphiphilic, Low‐swelling Hydrogels Treats Postoperative Inflammation in Cervical Spine Applications

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
DexaPatch, an implantable, low‐swelling amphiphilic hydrogel system containing dexamethasone‐PLGA microparticles, is developed and characterized for sustained local steroid release to reduce postoperative inflammation in tight surgical spaces. DexaPatch significantly reduces postoperative edema and fibrosis in a rabbit model of anterior spinal surgery,
Stephen W. Linderman, Graham F. Barber, S'Dravious A. DeVeaux, Edward A. Botchwey, Daniel Refai, Adam M. Klein, Andrés J. García   +6 more
wiley   +1 more source

Space medicine considerations: Skeletal and calcium homeostasis [PDF]

Based on the information obtained from space missions, particularly Skylab and the longer Salyut missions, it is clear that bone and mineral metabolism is substantially altered during space flight.
Schneider, Victor B.
core   +1 more source

Ptychographic X-ray nanotomography quantifies mineral distributions in human dentine [PDF]

, 2015
Bones are bio-composites with biologically tunable mechanical properties, where a polymer matrix of nanofibrillar collagen is reinforced by apatite mineral crystals.
Diaz, A., Dierolf, M., Enders, B., Gradl, R., Guizar-Sicairos, M., Menzel, A., Pfeiffer, F., Thibault, P., Zanette, I., Zaslansky, P.   +9 more
core   +2 more sources

Glucocorticoids Alter Bone Microvascular Barrier via MAPK/Connexin43 Mechanisms

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
Osteoporosis induced by Glucocorticoids (GCs) is a common complication of long‐term GC use in patients with inflammatory and autoimmune conditions, often leading to an increased fracture risk. A 3D bicellular endo‐osteo microfluidic platform is developed to explore pathogenic mechanisms underlying GCs‐induced osteoporosis, highlighting a novel MAPK ...
Eun‐Jin Lee, Peter Lialios, Micaila Curtis, James Williams IV, Yoontae Kim, Paul Salipante, Steven Hudson, Mandy B. Esch, Moshe Levi, Joanna Kitlinska, Stella Alimperti   +10 more
wiley   +1 more source

Bone mass of female dance students prior to professional dance training: A cross-sectional study [PDF]

, 2017
Article Authors Metrics Comments Related Content Abstract Introduction Methods Results Discussion Conclusions Acknowledgments References Reader Comments (0) Media Coverage (0) Figures Abstract Background Professional dancers are at risk of developing low
A Darelid, A Foldes, A Guadalupe-Grau, A Gómez-Bruton, A Nattiv, ADG Baxter-Jones, Alan M. Nevill, Andreas D. Flouris, BL Matthews, Carlos M. Isales, D Bliuc, D Pearson, DK Katzman, Eduardo Teixeira, FL Morris, Franklim Marques, G Vicente- Rodríguez, G Vicente-Rodríguez, George S. Metsios, H Kroger, HA McKay, JA Nurmi-Lawton, JA Shepherd, JAL Calbet, JB Richards, José Carlos Machado, José Maia, K Bennell, KG Faulkner, L Frederick, M Bradney, M Mountjoy, M Mughal, M Yannakoulia, Matthew Wyon, MK Torstveit, MP Warren, MP Warren, N Ma, N Young, NA Pocock, NM Morris, P Burckhardt, PB Crawford, R Valentino, RP Heaney, S Abraham, S Armann, S Hagiwara, S Ishikawa, T Amorim, T Chevalley, Tânia Amorim, WM Kohrt, Y Koutedakis, Y Koutedakis, Y Koutedakis, Y Koutedakis, Y Lu, Yiannis Koutedakis   +59 more
core   +1 more source

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source

Skeletal Maturity in Adolescence: Evaluating Bone Development and Age Metrics

Diagnostics
Background/Objectives: Bone maturation and development are crucial for growth and development, especially in children and adolescents; however, some qualitative methods, such as Greulich & Pyle, do not provide accurate data.
João Pinheiro, Luís Ribeiro, Diana Teixeira, Anabela Ribeiro, Manuel João Coelho-e-Silva   +4 more
doaj   +1 more source

Prediction of bone mineral density and content from measures of physical activity and sedentary behavior in younger and older females

Preventive Medicine Reports, 2015
Background: Little is known regarding the extent to which physical activity (PA) and sedentary behavior (SB) influence bone mineral content (BMC) and bone mineral density (BMD) in females across the lifespan. Methods: Data from 2232 females aged 12 years
Saori I. Braun, Youngdeok Kim, Amy E. Jetton, Minsoo Kang, Don W. Morgan   +4 more
doaj   +1 more source