3D Soft Hydrogels Induce Human Mesenchymal Stem Cells “Deep” Quiescence
Three‐dimensional soft hydrogels mimicking the bone marrow niche induce deep quiescence in human mesenchymal stem cells. Unlike 2D culture, 3D matrices halt proliferation, regulate cell‐cycle and quiescence markers, and downregulate mTORC1 signaling, preserving stem cell phenotype and therapeutic potential ex vivo.
David Boaventura Gomes +11 more
wiley +1 more source
Bone mass, muscle-bone unit, and bone turnover markers in healthy preadolescent Malaysian children [PDF]
Purpose Normative values of bone mass, bone turnover markers (BTMs) and muscle-bone unit (MBU) among healthy Asian children are needed to enable accurate skeletal assessment.
Kanimolli Arasu +2 more
doaj +1 more source
Skeletal status and soft tissue composition in astronauts. Tissue and fluid changes by radionuclide absorptiometry in vivo [PDF]
A device has been constructed and tested which provides immediate readout of bone mineral content and bone width from absorptiometric scans with low energy radionuclides.
Cameron, J. R. +2 more
core +1 more source
Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su +8 more
wiley +1 more source
Skeletal Maturity in Adolescence: Evaluating Bone Development and Age Metrics
Background/Objectives: Bone maturation and development are crucial for growth and development, especially in children and adolescents; however, some qualitative methods, such as Greulich & Pyle, do not provide accurate data.
João Pinheiro +4 more
doaj +1 more source
Epidermal Patch Technologies for Integrated Healthcare and Infection Management
Epidermal patches have evolved from simple wound coverings into multifunctional, skin‐conformable platforms integrating drug delivery, biosensing, and therapeutic functionalities. This review highlights their material innovations, fabrication strategies, and intelligent designs, including hydrogels, microneedles, and flexible electronics, while ...
Yuqi Wang +7 more
wiley +1 more source
Evaluation of bone mineral density in urban girls of Kawar-Fars
Background: Normal bone structure is formed in childhood and adolescence. Any problem of bone formation at these stages will lead to significant osteoporosis and its complications in adulthood.
Marjan Jeddi +5 more
doaj
ObjectiveMeta-analysis was used to evaluate the effects of an exercise intervention on bone mineral content (BMC), bone mineral density (BMD), and bone metabolism in adolescents.MethodsA systematic search of PubMed, Embase, Cochrane Library, and Web of ...
Wenhua Zhang +6 more
doaj +1 more source
Measurement of bone quality in growing male rats using dual energy x-ray absorptiometry and bone ash content : a thesis presented in partial fulfilment of the requirements for the degree of Master of Applied Science in Animal Science at Massey University, Palmerston North, New Zealand [PDF]
Growing male rats have been considered and used as a model for bone growth and prevention of osteoporosis because of their high bone turnover and demand for calcium. Dual Energy X-ray Absorptiometry (DEXA) is a useful tool for identifying minimal changes
Brown, Katherine Elizabeth
core
Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa +3 more
wiley +1 more source

