Results 121 to 130 of about 505,690 (397)
Microphysiological Systems for Comorbidity Studies: Chronic Kidney Disease and Osteoarthritis
This review highlights the potential of organ‐on‐a‐chip systems for studying comorbidities, using chronic kidney disease (CKD) and osteoarthritis (OA) as examples. It summarizes recent advances in kidney‐on‐a‐chip and joint‐on‐a‐chip models and discusses their current and potential application in investigating CKD, OA, and CKD‐OA comorbidity, aiming to
Mingying Han+7 more
wiley +1 more source
Bone is heterogeneous and anisotropic because its mechanical characteristics vary by anatomic location and loading direction. Previous research established a correlation between bone density, mineral, organic content, and porosity and mechanical ...
Sachin Kalsi+8 more
doaj
Preventative ibandronate treatment has the most beneficial effect on the microstructure of bone in experimental tumor osteolysis [PDF]
We investigated the effect of ibandronate on three-dimensional (3-D) microstructure and bone mass in experimentally induced tumor osteolysis. Walker carcinosarcoma cells were implanted into the left femur of female rats that received 26-day ibandronate ...
Bauss, Frieder+5 more
core
Serum Calcitonin and Bone Mineral Content in Patients with Osteogenesis Imperfecta [PDF]
H. E. Nielsen+3 more
openalex +1 more source
Bone fracture healing is a complex, timely orchestrated scenario involving multiple cell types and a plethora of cytokines and regulatory factors. To gain further insight, an in vitro model to a) study macrophage polarization under mechanical load in a fibrin hydrogel and b) subsequently assess the effect of conditioned media derived from macrophages ...
Anne Géraldine Guex+4 more
wiley +1 more source
Weight-bearing bones are more sensitive to physical exercise in boys than in girls during pre- and early puberty: a cross-sectional study [PDF]
Summary: We carried out a cross-section study of the sex-specific relationship between bone mineral content and physical activity at sites with different loading in pre- and early pubertal girls and boys. There was significant sensitivity of bone mineral
Braun-Fahrländer, C.+7 more
core
Mechanisms of morphogenetic disorders in the lower jaw under the influence of heavy metal salts on the body [PDF]
In the experiment on the 36 mature rats, the peculiarities of morphological disorders in the lower jaw of rats under the influence of salts of chromium, lead, zinc, iron, copper, and manganese are showed.
Korobchanska, Anna Borysivna+11 more
core +1 more source
Si Inhibited Osteoclastogenesis: The Role of Fe and the Fenton Reaction
Silicate (Si) inhibition of osteoclastogenesis, is mediated by Fe. Si chemical interactions with Fe inhibit the Fenton reaction and intercellular ROS availability. This reduction in ROS availability inhibits osteoclastogenesis. The addition of Fe, in Si‐inhibited osteoclast cultures, restores the Fenton reaction, and osteoclastogenesis.
Yutong Li+7 more
wiley +1 more source
Bone mineral density in human femurs of documented age-at-death in a comparative context
This contribution aims at answering the question of the how and the why of invasive, micro-invasive and non-invasive analysis of anthropobiological remains, through the study of a collection comprising 51 skeletons of known age and sex (27 males and 24 ...
Emmanuel Gilissen+2 more
doaj +1 more source
Changes in the volumetric bone mineral density (vBMD) and bone mineral content (BMC) of tibiotarsal bones of growing turkeys as affected by birds' age, sex, and within-the-bone location, respectively, were determined by computed tomography.
A. Charuta+3 more
doaj +1 more source