Results 131 to 140 of about 53,845 (250)

Alteration in oral and non‐oral tissues in ligature‐induced periodontitis mice with the Alzheimer's disease risk factor APOE4

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract The APOE4 gene, particularly the ε4 allele, is linked to susceptibility to Alzheimer's disease, and periodontitis can cause pathological changes in multiple organs, but combined effects of these conditions and the impact of tumor necrosis factor (TNF)‐α regulation on the combined effects remain unclear.
Ae Ri Kim   +2 more
wiley   +1 more source

Effect of aging on healing of mandibular tooth extraction socket in a rat model

open access: yesEuropean Journal of Oral Sciences, EarlyView.
Abstract This study evaluated the effect of aging on bone regeneration in mandibular extraction sockets. Male Sprague–Dawley rats were divided into three age groups: 2‐month‐old (2 M, n = 6), 10‐month‐old (10 M, n = 6), and 18‐month‐old (18 M, n = 5). Two weeks post‐extraction, comprehensive analyses were performed using micro‐computed tomography (µ‐CT)
Kyung Su Shin   +7 more
wiley   +1 more source

Renal function in African women receiving tenofovir disoproxil fumarate as pre‐exposure prophylaxis for HIV during pregnancy and postpartum: A postpartum safety analysis in the CAP016 randomized control trial

open access: yesHIV Medicine, EarlyView.
Abstract Background The effect of tenofovir disoproxil fumarate (TDF) when used as pre‐exposure prophylaxis (PrEP) on renal function in pregnant and postpartum women is understudied. An open‐label clinical trial (CAP016 study) was designed to examine the safety of TDF‐PrEP use during pregnancy and breastfeeding.
Gaysheen Kistan   +5 more
wiley   +1 more source

PMH8 EFFECT OF VARIOUS ANTIDEPRESSANT GROUPS ON BONE MINERAL DENSITY (BMD) [PDF]

open access: yesValue in Health, 2011
Kurmanji, J.M.   +3 more
openaire   +1 more source

Screening for bone health in older people with HIV: Uptake and outcomes from a large UK outpatient HIV service

open access: yesHIV Medicine, EarlyView.
Abstract Objectives Bone health is negatively affected in people with HIV, and the risks of osteoporosis and fragility fractures are increased. The objective of this study was to describe the characteristics of those accessing bone health screening and identify factors associated with osteoporosis.
Rhys Nicholas   +3 more
wiley   +1 more source

Bone health in adults with non‐ambulatory neuromuscular disorders: scoping review of risk factors, diagnosis and management

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Non‐ambulatory adults have an increased risk of osteoporosis and fractures due to reduced weight‐bearing and diminished neuromuscular stimulation, resulting in substantial morbidity and mortality. Aims This scoping review aimed to systematically evaluate risk factors, diagnostic indicators and management strategies for optimising ...
Thomas Bailey   +4 more
wiley   +1 more source

Denosumab discontinuation and fracture risk: getting the balance right

open access: yesInternal Medicine Journal, EarlyView.
Abstract Denosumab is a highly effective therapy for osteoporosis. Since its approval by the Therapeutic Goods Administration (TGA) in 2010, use of denosumab has surged across Australia, delivering substantial fracture‐prevention benefits to tens of thousands of patients. However, stopping denosumab may lead to acute loss of bone with an increased risk
Albert S. Kim, Christian M. Girgis
wiley   +1 more source

Cumulative effects of lifelong systemic excess growth hormone on postcranial skeletal morphology in adult mice

open access: yesJournal of Anatomy, EarlyView.
Our μCT‐based pilot study reveals size and shape disparity in the adult postcranial skeleton of growth‐hormone model (bGH) mice relative to wild‐type mice. bGH mice have larger and more sexually dimorphic bones, with a systemic radiodensity increase in bony sesamoids and associated, but typically uncalcified, soft tissues.
Joseph R. Groenke   +7 more
wiley   +1 more source

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