Bone morphogenetic protein 7 promotes resistance to immunotherapy [PDF]
Nature Communications, 2020 The mechanisms underlying resistance to immunotherapy are still poorly understood. Here, the authors show that BMP7, a molecule part of the TGF-beta superfamily, suppresses proinflammatory antitumor responses and may represent a target for overcoming ...
Maria Angelica Cortez +17 more
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Role of bone morphogenetic protein-7 in renal fibrosis [PDF]
Frontiers in Physiology, 2015 Renal fibrosis is final common pathway of end stage renal disease. Irrespective of the primary cause, renal fibrogenesis is a dynamic process which involves a large network of cellular and molecular interaction, including pro-inflammatory cell ...
Rui Xi eLi, Sydney C.W. eTang
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Bone morphogenetic protein 7 (BMP-7) influences tendon-bone integration in vitro. [PDF]
PLoS ONE, 2015 INTRODUCTION:Successful graft ingrowth following reconstruction of the anterior cruciate ligament is governed by complex biological processes at the tendon-bone interface.
Tim Schwarting +7 more
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Bone Morphogenetic Protein 7 Effect on Human Glioblastoma Cell Transmigration and Migration [PDF]
Life, 2021 Glioblastoma, World Health Organization—grade IV, is the most malignant glioma type and it is still an incurable tumor due to the high level of heterogeneity and uncontrolled metastatic nature. In addition to the tumorigenicity-suppressing activity, bone
Ting-Chung Wang +2 more
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Author Correction: Bone morphogenetic protein 7 promotes resistance to immunotherapy [PDF]
Nature Communications, 2020 An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Maria Angelica Cortez +17 more
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Bone Morphogenetic Protein 7 Promotes the Differentiation of Periodontal Ligament Fibroblasts into F-Spondin-Expressing Cementoblast-like Cells During Root Canal Treatment—An In Vivo Rat Pulpectomy Model and In Vitro Human Fibroblast Study [PDF]
Dentistry JournalBackground/Objectives: The optimal healing process following root canal treatment involves biological apical sealing through new cementum formation.
Hiroki Iwasawa +5 more
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The Role of Bone Morphogenetic Protein 7 (BMP-7) in Inflammation in Heart Diseases [PDF]
Cells, 2020 Bone morphogenetic protein-7 is (BMP-7) is a potent anti-inflammatory growth factor belonging to the Transforming Growth Factor Beta (TGF-β) superfamily.
Chandrakala Aluganti Narasimhulu +1 more
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Bone morphogenetic protein 7 mediates stem cells migration and angiogenesis: therapeutic potential for endogenous pulp regeneration [PDF]
International Journal of Oral Science, 2022 BMP7 as a regenerative signaling molecule mediates stem cell migration and odontoblastic differentiation (a) and as a pro-angiogenic factor promotes revascularization of endothelial cells (b). Collagen gel supports cell adhesion, spreading, and viability
Cheng Liang +11 more
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Muscle injury promotes heterotopic ossification by stimulating local bone morphogenetic protein-7 production [PDF]
Journal of Orthopaedic Translation, 2019 Background: Heterotopic ossification (HO) is a pathological condition of abnormal bone formation in soft tissue, which causes pain and restricted range of motion in patients. There are two broad categories of HO, hereditary and acquired.
La Li +6 more
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Effects of Bone Morphogenetic Protein‐7 on Steroid‐Induced Extracellular Matrix Accumulation in Human Trabecular Meshwork Cells [PDF]
FASEB BioAdvancesLong‐term steroid use, though essential for treating eye diseases, can cause increased intraocular pressure (IOP) in susceptible individuals and may lead to steroid‐induced glaucoma in a subset of patients.
Eun Woo Kim +9 more
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