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Bone Morphogenetic Proteins Shape Treg Cells [PDF]
The transforming growth factor-β (TGF-β) family includes cytokines controlling cell behavior, differentiation and homeostasis of various tissues including components of the immune system.
Piotr Kraj
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Bone Morphogenetic Proteins and Diabetic Retinopathy [PDF]
Bone morphogenetic proteins (BMPs) play an important role in bone formation and repair. Recent studies underscored their essential role in the normal development of several organs and vascular homeostasis in health and diseases.
Khaled Elmasry +3 more
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Insights into bone morphogenetic proteins in cardiovascular diseases [PDF]
Bone morphogenetic proteins (BMPs) are secretory proteins belonging to the transforming growth factor-β (TGF-β) superfamily. These proteins play important roles in embryogenesis, bone morphogenesis, blood vessel remodeling and the development of various ...
Di Ye +21 more
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The Prognostic Value of Bone Morphogenetic Proteins and Their Receptors in Lung Adenocarcinoma [PDF]
BackgroundBone morphogenetic proteins (BMPs) regulate tumor progression via binding to their receptors (BMPRs). However, the expression and clinical significance of BMPs/BMPRs in lung adenocarcinoma remain unclear due to a lack of systematic studies ...
Wangyang Meng +8 more
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A Comprehensive Review Exploring the Role of Bone Morphogenetic Proteins [BMP]: Biological Mechanisms [PDF]
Bone morphogenetic proteins (BMPs) belong to the TGF-β family. They perform diverse roles in development, osteogenesis, and vasculogenesis. BMPs have crucial functions in embryonic development and regulate the specialization of various cell types.
Akanksha A. Kalal, Satyajit Mohapatra
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Abstract BMP2 and BMP4 play crucial inductive roles during development. In this issue of Blood, Shao et al demonstrate that an intricate network of paracrine BMP2/4 signals also regulates angiogenesis—and will very likely interact with endocrine BMP cues during wound repair ...
exaly +4 more sources
The Dual Role of Bone Morphogenetic Proteins in Cancer
Bone morphogenetic proteins (BMPs) are a diverse class of molecules with over 20 growth factor proteins that belong to the transforming growth factor-β (TGF-β) family and are highly associated with bone formation and disease development.
Duc-Hiep Bach +2 more
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Bone morphogenetic proteins: Their role in regulating osteoclast differentiation [PDF]
The ability to create recombinant bone morphogenetic proteins (BMPs) in recent years has led to their rise as a common clinical adjuvant. Their application varies, from spinal fixation to repairing palatal clefts, to coating implants for osseointegration.
Raphael Huntley +3 more
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Bone Morphogenetic Proteins, Carriers, and Animal Models in the Development of Novel Bone Regenerative Therapies [PDF]
Nikola Stokovic +2 more
exaly +2 more sources
Increased BMP-Smad signaling does not affect net bone mass in long bones
Bone morphogenetic proteins (BMPs) have been used for orthopedic and dental application due to their osteoinductive properties; however, substantial numbers of adverse reactions such as heterotopic bone formation, increased bone resorption and greater ...
Maiko Omi +5 more
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