Results 11 to 20 of about 69,320 (294)

The family of bone morphogenetic proteins [PDF]

Kidney International, 2000
The family of bone morphogenetic proteins. Bone morphogenetic proteins (BMPs) are secreted signaling molecules belonging to the transforming growth factor-beta (TGF-beta) superfamily of growth factors. The first BMPs were originally identified by their ability to induce ectopic bone formation when implanted under the skin of rodents.
Ducy, Patricia, Karsenty, Gerard
openaire   +3 more sources

Bone morphogenetic proteins: Signaling periodontal bone regeneration and repair

Journal of Pharmacy and Bioallied Sciences, 2016
Bone morphogenetic proteins (BMPs) are a group of growth factors also known as cytokines and as metabologens. Originally discovered by their ability to induce the formation of bone and cartilage, BMPs are now considered to constitute a group of pivotal ...
G Sai Anusuya, M Kandasamy, S A Jacob Raja, S Sabarinathan, P Ravishankar, Balu Kandhasamy   +5 more
doaj   +2 more sources

Bone morphogenetic proteins: The anomalous molecules

Journal of Indian Society of Periodontology, 2013
Bone is unique of all the tissues in the vertebrate organism. When injured, it heals by formation of new bone. Bone morphogenetic proteins (BMPs) are powerful inductors of the osteogenic activity during the embryologic bone formation phase and in cases ...
Aena Pundir Jain, Siddharth Pundir, Anamika Sharma   +2 more
doaj   +2 more sources

DP2, a Carbohydrate Derivative, Enhances In Vitro Osteoblast Mineralisation

Pharmaceuticals, 2023
Bone fracture healing is a complex biological process involving four phases coordinated over time: hematoma formation, granulation tissue formation, bony callus formation, and bone remodelling.
Nissrine Ballout, Agnès Boullier, Walaa Darwiche, Katia Ait-Mohand, Eric Trécherel, Théo Gallégo, Cathy Gomila, Linda Yaker, Isabelle Gennero, José Kovensky, Jérôme Ausseil, Sylvestre Toumieux   +11 more
doaj   +1 more source

The risk of tumor with the use of recombinant human bone morphogenetic proteins

Гений oртопедии, 2022
Introduction Bone morphogenetic proteins (BMPs) are members of a large family of growth factors known as the transforming growth factor-β (TGF-β) superfamily. BMPs are known for their ability to induce bone formation and successfully used in orthopaedic
Ural F. Mukhametov, Sergey V. Lyulin, Dmitry Yu. Borzunov, Rinat A. Sufianov, Ilgiz F. Gareev   +4 more
doaj   +1 more source

The Classic: Bone Morphogenetic Protein [PDF]

Clinical Orthopaedics and Related Research®, 2009
This Classic Article is a reprint of the original work by Marshall R. Urist and Basil S. Strates, Bone Morphogenetic Protein. An accompanying biographical sketch of Marshall R. Urist, MD is available at DOI 10.1007/s11999-009-1067-4; a second Classic Article is available at DOI 10.1007/s11999-009-1069-2; and a third Classic Article is available at DOI ...
Urist, Marshall R., Strates, Basil S.
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The effect of simvastatin on the regeneration of surgical cavities in the femurs of rabbits [PDF]

Acta Cirúrgica Brasileira, 2014
PURPOSE:To evaluate the effect of a local application of simvastatin gel in repairing bone defects in the femurs of rabbits.METHODS:Two standard surgical cavities were created in the femoral epiphysis of 18 rabbits.
José Eduardo Gomes Cardim Rosselli, Dulce Maria Fonseca Soares Martins, José Luiz Martins, Claudia Regina Gomes Cardim Mendes de Oliveira, Djalma José Fagundes, Murched Omar Taha   +5 more
doaj   +1 more source

Nuclear variants of bone morphogenetic proteins

BMC Cell Biology, 2010
Background Bone morphogenetic proteins (BMPs) contribute to many different aspects of development including mesoderm formation, heart development, neurogenesis, skeletal development, and axis formation.
Meinhart Christopher A, Gaufin Stephanie L, Sperry Daniel K, Jensen J Daniel, Loos Trina J, Mayo Jaime L, Felin Jenny E, Moss Jennie B, Bridgewater Laura C   +8 more
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Protein associated with SMAD1 (PAWS1/FAM83G) is a substrate for type I bone morphogenetic protein receptors and modulates bone morphogenetic protein signalling [PDF]

, 2014
Bone morphogenetic proteins (BMPs) control multiple cellular processes in embryos and adult tissues. BMPs signal through the activation of type I BMP receptor kinases, which then phosphorylate SMADs 1/5/8.
Smith, James C., Lina Herhaus, Janis Vogt, Gopal P. Sapkota, Gourlay, Robert, Macartney, Thomas, Campbell, David, Vogt, Janis, Herhaus, Lina, Sapkota, Gopal P., David Campbell, James C. Smith, Dingwell, Kevin S., Thomas Macartney, Kevin S. Dingwell, Robert Gourlay   +15 more
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USP15 targets ALK3/BMPR1A for deubiquitylation to enhance bone morphogenetic protein signalling [PDF]

, 2014
Protein kinase ALK3/BMPR1A mediates bone morphogenetic protein (BMP) signalling through phosphorylation and activation of SMADs 1/5/8. SMAD6, a transcriptional target of BMP, negatively regulates the BMP pathway by recruiting E3 ubiquitin ligases and ...
Bruce, David, Smith, James C., Dingwell, Kevin S., Cummins, Timothy D., Ewan, Richard, Macartney, Thomas, Al-Salihi, Mazin A., Weidlich, Simone, Vogt, Janis, Herhaus, Lina, Sapkota, Gopal P., Wasmus, Lise   +11 more
core   +1 more source