Results 21 to 30 of about 64,844 (152)

Generation of optimized preparations of bone morphogenetic proteins for bone regeneration [PDF]

The Ukrainian Biochemical Journal, 2016
Correction of inherited skeletal abnormalities, traumas affecting wide bone areas and non-healing fractures require efficient bone formation and regeneration.
Kh. V. Malysheva, I. M. Spasyuk, O. K. Pavlenko   +2 more
doaj   +1 more source

Bone morphogenetic protein-2 influence on metabolic activity and proteoglycan synthesis by intervertebral disc cells

Acta Biomedica Scientifica, 2016
Modern therapeutic strategies for intervertebral disc repair mainly focus on targeting molecular pathways of extracellular matrix degeneration. Anabolic strategies for regeneration are aimed to increase production of major extracellular molecules ...
L. A. Bardonova, E. G. Belykh, V. A. Byvaltsev   +2 more
doaj   +1 more source

Heterodimeric BMP-2/7 antagonizes the inhibition of all-trans retinoic acid and promotes the osteoblastogenesis. [PDF]

PLoS ONE, 2013
OBJECTIVES: Hypervitaminosis A and alcoholism can result in a low mineral density and compromised regenerative capacity of bone, thus delaying implant osteointegration.
Wenjuan Bi, Zhiyuan Gu, Yuanna Zheng, Xiao Zhang, Jing Guo, Gang Wu   +5 more
doaj   +1 more source

Association of Bone Morphogenetic Proteins With Otosclerosis [PDF]

Journal of Bone and Mineral Research, 2008
Abstract We studied the role of polymorphisms in 13 candidate genes on the risk of otosclerosis in two large independent case-control sets. We found significant association in both populations with BMP2 and BMP4, implicating these two genes in the pathogenesis of this disease.
Schrauwen, Isabelle, Thys, Melissa, Vanderstraeten, Kathleen, Fransen, Erik, Dieltjens, Nele, Huyghe, Jeroen R., Ealy, Megan, Claustres, Mireille, Cremers, Cor R.W.J., Dhooge, Ingeborg, Declau, Frank, Van de Heyning, Paul, Vincent, Robert, Somers, Thoams, Offeciers, Erwin, Smith, Richard J.H., Van Camp, Guy   +16 more
openaire   +3 more sources

Effects of bioactive glass S53P4 or beta-tricalcium phosphate and bone morphogenetic protein-2 and bone morphogenetic protein-7 on osteogenic differentiation of human adipose stem cells

Journal of Tissue Engineering, 2012
The effects of bioactive glass S53P4 or beta-tricalcium phosphate; and bone morphogenetic proteins bone morphogenetic protein-2, bone morphogenetic protein-7, or bone morphogenetic protein-2 + 7 on osteogenic differentiation of human adipose stem cells ...
Martin Waselau, Mimmi Patrikoski, Miia Juntunen, Kasperi Kujala, Minna Kääriäinen, Hannu Kuokkanen, George K Sándor, Outi Vapaavuori, Riitta Suuronen, Bettina Mannerström, Brigitte von Rechenberg, Susanna Miettinen   +11 more
doaj   +1 more source

Current Methods for the Treatment of Alveolar Cleft

Archives of Plastic Surgery, 2017
Alveolar cleft is a tornado-shaped bone defect in the maxillary arch. The treatment goals for alveolar cleft are stabilization and provision of bone continuity to the maxillary arch, permitting support for tooth eruption, eliminating oronasal fistulas ...
Nak Heon Kang
doaj   +1 more source

Induction of bone formation in abdominal implants constituted by collagen sponges embedded with plant‐based human transforming growth factor family proteins in ectopic dog model

Journal of Experimental Orthopaedics, 2014
Background Trauma, osteomyelitis, bone tumour resections and congenital deformities are the main causes of bone deficiency in which autologous graft is the preferred treatment, but usually the bone supplies are limited.
Juan Carlos Jacinto‐Tinajero, Daniel Ascencio, Brenda Marquina, Jorge Barrios‐Payán, Maria Concepcion Gutierrez, Miguel Gomez Lim, Rogelio Hernández Pando   +6 more
doaj   +1 more source

Structural and Metabolic Changes in Bone

Animals, 2022
As an essential component of the skeleton, bone tissue provides solid support for the body and protects vital organs. Bone tissue is a reservoir of calcium, phosphate, and other ions that can be released or stored in a controlled manner to provide ...
Agata Wawrzyniak, Krzysztof Balawender
doaj   +1 more source

Genetics of ovulation rate in farm animals [PDF]

Veterinary World, 2013
Rate of ovulation (i.e. fecundity) is largely influenced by both genetic and environmental factors. The ovarian growth factorsincluding members of bone morphogenetic proteins (BMPs) play a central role in determining ovulation quota and litter size ...
Rohit Kumar, Sanjeev Kumar Sharma, R. Kumar Pramod, Anju Rajan   +3 more
doaj   +1 more source

Functional analysis of alleged NOGGIN mutation G92E disproves its pathogenic relevance.

PLoS ONE, 2012
We identified an amino acid change (p.G92E) in the Bone Morphogenetic Protein antagonist NOGGIN in a 22-month-old boy who presented with a unilateral brachydactyly type B phenotype. Brachydactyly type B is a skeletal malformation that has been associated
Julia Zimmer, Sandra C Doelken, Denise Horn, Jay C Groppe, Eileen M Shore, Frederick S Kaplan, Petra Seemann   +6 more
doaj   +1 more source