Results 41 to 50 of about 64,844 (152)

Cloning of BMP-2 Gene and Its Expression Study in E. coli in Order to Produce a Recombinant Drug

پزشکی بالینی ابن سینا, 2014
Introduction & Objective: Bone morphogenetic proteins are a group of cytokines that belongs to superfamily TGFβ. These proteins play an important role in evolution of many of organs and tissues through germinal period followed by amending and rebuilding ...
Nejad Mohammadi, Jamshid Karimi, Nooshin Shabab, Samaneh Naderi, Reza Yadegar Azari, Masoud Saidijam   +5 more
doaj  

Heterotopic ossification as a side effect of the use of recombinant human bone morphogenetic proteins

Гений oртопедии, 2022
Introduction Heterotopic ossification (HO), also known as myositis ossification, paraosteoarthropathy, or heterotopic calcification, among others, is a common pathological condition that refers to ectopic bone formation in soft tissues.
Ural F. Mukhametov, Sergey V. Lyulin, Dmitry Yu. Borzunov, Ilgiz F. Gareev, Ozal Arzuman Beylerli, Albert A. Sufianov   +5 more
doaj   +1 more source

Efficacy of copolymer scaffolds delivering human demineralised dentine matrix for bone regeneration

Journal of Tissue Engineering, 2019
Poly(L-lactide-co-ε-caprolactone) scaffolds were functionalised by 10 or 20 µg/mL of human demineralised dentine matrix. Release kinetics up to 21 days and their osteogenic potential on human bone marrow stromal cells after 7 and 21 days were studied.
Arooj Munir, Anne Døskeland, Steven J Avery, Tiziana Fuoco, Samih Mohamed-Ahmed, Henning Lygre, Anna Finne-Wistrand, Alastair J Sloan, Rachel J Waddington, Kamal Mustafa, Salwa Suliman   +10 more
doaj   +1 more source

Effects of recombinant human bone morphogenetic protein-2 compared to other biomaterials in the treatment of intrabony defects in periodontitis patients: A systematic review

Journal of Indian Society of Periodontology, 2019
Background: Bone morphogenetic proteins have a powerful osteoinductive capacity and have been used as a new adjunct to graft materials for bone regeneration.
Raghavendra Shrishail Medikeri, Vinayak Venkoosa Meharwade, Kumar Ankit Sinha   +2 more
doaj   +1 more source

Bone morphogenetic proteins: from structure to clinical use

Brazilian Journal of Medical and Biological Research, 2005
Bone morphogenetic proteins (BMPs) are multi-functional growth factors belonging to the transforming growth factor ß superfamily. Family members are expressed during limb development, endochondral ossification, early fracture, and cartilage repair.
Granjeiro J.M., Oliveira R.C., Bustos-Valenzuela J.C., Sogayar M.C., Taga R.   +4 more
doaj  

E proteins sharpen neurogenesis by modulating proneural bHLH transcription factors’ activity in an E-box-dependent manner

eLife, 2018
Class II HLH proteins heterodimerize with class I HLH/E proteins to regulate transcription. Here, we show that E proteins sharpen neurogenesis by adjusting the neurogenic strength of the distinct proneural proteins.
Gwenvael Le Dréau, René Escalona, Raquel Fueyo, Antonio Herrera, Juan D Martínez, Susana Usieto, Anghara Menendez, Sebastian Pons, Marian A Martinez-Balbas, Elisa Marti   +9 more
doaj   +1 more source

The first approved drug for abnormal bone formation: palovarotene challenges and way forward

Journal of the Pakistan Medical Association
The current communication was planned to assess the validity of a potential cure for two disorders of bone formation that have traditionally been limited to symptomatic treatment in orthopaedic medicine.
Hassam Nasir Khan Alizai, Aainah Pasha, Parsa Khan Alizai, Namra Zia   +3 more
doaj   +1 more source

Pulmonary artery hypertension in childhood: The transforming growth factor-β superfamily-related genes

Pediatrics and Neonatology, 2018
Pulmonary artery hypertension (PAH) is very rare in childhood, and it can be divided into heritable, idiopathic drug- and toxin-induced and other disease (connective tissue disease, human immunodeficiency virus infection, portal hypertension, congenital ...
Shi-Min Yuan
doaj   +1 more source

Bone morphogenetic protein signaling in bone homeostasis

Bone, 2015
Bone morphogenetic proteins (BMPs) are cytokines belonging to the transforming growth factor-β (TGF-β) superfamily. They play multiple functions during development and tissue homeostasis, including regulation of the bone homeostasis. The BMP signaling pathway consists in a well-orchestrated manner of ligands, membrane receptors, co-receptors and ...
Sanchez Duffhues, G., Hiepen, C., Knaus, P., Dijke, P. ten   +3 more
openaire   +3 more sources

Glypicans Dally and Dally-like control injury-induced allodynia in

Molecular Pain, 2019
Over 100 million people are challenged by the effects of chronic pain in the United States alone. This burden also impacts the U.S. economy; 600 billion dollars annually is spent on medical care, medications, and lost productivity in the workplace ...
Courtney L Brann, Julie K Moulton, Geoffrey K Ganter   +2 more
doaj   +1 more source