Results 121 to 130 of about 116,690 (300)

Control of cell division in the adult brain by heparan sulfates in fractones and vascular basement membranes [PDF]

, 2010
Regulation of cell division in adult tissues and organs requires the coordination of growth factors at the surface of potentially-dividing cells in specific anatomic loci named germinal niches.
Frederic Mercier, Vanessa Douet
core   +1 more source

Genotypes and Phenotypes of Patients With TSPEAR‐Related Disorder: Evidence of a Predominant Dental Phenotype

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT TSPEAR (chr. 21q22.3) encodes a protein involved in tooth development and is predominantly expressed in the enamel knot. Biallelic loss of function variants in TSPEAR cause ectodermal dysplasia, tooth agenesis and sensorineural hearing loss. However, the role of TSPEAR in auditory processes is unclear.
Debora Vergani, Lucia Tiberi, Annarita Giliberti, Elia Dirupo, Laila Zaroili, Francesco Brancati, Michela Brena, Stefano Caraffi, Chiara De Luca, Livia Garavelli, Anna Virginia Gulino, Milena Mariani, Marzia Pollazzon, Angelo Selicorni, Samuela Landini, Ilaria Sani, Rosangela Artuso, Angela Peron   +17 more
wiley   +1 more source

An elastic segment of the whisker shaft enables coding of the whisking phase via whisker torsion in rats and mice

The Anatomical Record, EarlyView.
An elastic segment was found in the basal part of the whisker shaft in rats and mice. Application of force to the whisker bulb of isolated follicles caused bending and twisting of this segment. Active whisker movements deform this segment, causing whisker shaft deflection and selective activation of mechanoreceptors at different phases of whisking ...
Sebastian Haidarliu, Guy Nelinger, Luka Gantar, Ehud Ahissar, Inbar Saraf‐Sinik   +4 more
wiley   +1 more source

Growth factor-mediated augmentation of long bones: evaluation of a BMP-7 loaded thermoresponsive hydrogel in a murine femoral intramedullary injection model

Journal of Orthopaedic Surgery and Research, 2019
Background Due to our aging population, an increase in proximal femur fractures can be expected, which is associated with impaired activities of daily living and a high risk of mortality.
Carl Neuerburg, Lena M. Mittlmeier, Alexander M. Keppler, Ines Westphal, Änne Glass, Maximilian M. Saller, Philipp K. E. Herlyn, Heiko Richter, Wolfgang Böcker, Matthias Schieker, Attila Aszodi, Dagmar-C. Fischer   +11 more
doaj   +1 more source

Potential of bone morphogenetic protein-7 in treatment of lupus nephritis: addressing the hurdles to implementation. [PDF]

Inflammopharmacology, 2023
Smith C, du Toit R, Ollewagen T.
europepmc   +1 more source

Bone Morphogenetic Protein-7 and disease progression in renal amyloidosis patients

Renal Failure, 2013
Chronic kidney disease (CKD) is an important health care problem with increasing incidence. Early diagnosis, recognition and interventions to avoid the disease progression have great value. Even some risk factors for disease progression have been described; there are still some dark spots.
Nazım, Denizli, Alper, Azak, Murat, Şakacı, Bülent, Huddam, Gülay, Koçak, Mehmet Fatih, Akdoğan, Recep, Demirci, Murat, Gücün, Levent, Ortabozkoyun, Yasemin, Fidan, İbrahim, Akdağ, Murat, Duranay   +11 more
openaire   +2 more sources

Evaluation of IHH, PTCH1, and SMO protein immunohistochemistry in the human mandibular condyle at fetal stages from 30 to 80 mm greatest length

The Anatomical Record, EarlyView.
Abstract This study evaluated the morphogenesis of the temporomandibular joint (TMJ) in human fetuses during the third month of gestation through the analysis of immunohistochemistry for the proteins Indian Hedgehog (IHH), Patched‐1 (PTCH1), and Smoothened (SMO).
Filipe Santos da Silva, Carolina de Oliveira Gigek, Andreia Fabiana Do Vale Franco, Amanda Alves Ribeiro Massoni, José Ramon Mérida‐Velasco, Luís Otávio Carvalho de Moraes   +5 more
wiley   +1 more source

Predictive value of bone morphogenetic protein-7, thromboxane A2, and osteoprotegerin for prognosis of patients with distal radius fractures. [PDF]

Jt Dis Relat Surg, 2023
Jing S, Wang Y, Meng X, Shang X, Zhu H, Sun X.   +5 more
europepmc   +1 more source

Serum Proteomic Signatures of RA Risk and Response: Analysis of the APIPPRA Trial

Arthritis &Rheumatology, Accepted Article.
Objective To identify serum protein signatures associated with progression to rheumatoid arthritis (RA) and response to abatacept in at‐risk individuals. Methods A total of 440 serum samples from 118 APIPPRA study participants were selected from baseline to RA onset for 46 RA progressors or to study end for 72 participants who did not develop RA ...
Marianna Jasenecova, Carl Coyle, Alina Mihalovits, Sarah Ryan, Elizabeth Pook, Esperanza Perucha, Gabrielle Harker, Melody Chin, Sam Norton, Andrew P. Cope   +9 more
wiley   +1 more source

In vivo delivery of Gremlin siRNA plasmid reveals therapeutic potential against diabetic nephropathy by recovering bone morphogenetic protein-7.

PLoS ONE, 2010
Diabetic nephropathy is a complex and poorly understood disease process, and our current treatment options are limited. It remains critical, then, to identify novel therapeutic targets.
Qingxian Zhang, Yonghong Shi, Jun Wada, Sandra M Malakauskas, Maodong Liu, Yunzhuo Ren, Chunyang Du, Huijun Duan, Yingmin Li, Ying Li, Yanling Zhang   +10 more
doaj   +1 more source